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Biomedical subjects

G G Erichsen

Publications and source records attributed to G G Erichsen.

10 recordsLinked to original sources

Selection of women at high risk of breast cancer using two lifestyle markers: a case control study.

OBJECTIVE: To select a population of women with high risk of invasive breast cancer by using two markers of high risk lifestyle--age at first delivery > = 25 and daily alcohol intake > = 7 g. DESIGN: Case control study based on a structural interview. SETTING: Two general practices in Copenhagen, Denmark. PARTICIPANTS: 30 patients with invasive breast cancer and 30 age-matched controls. MAIN OUTCOME MEASURE: The combined selection power of the two markers of high risk lifestyle. RESULTS: The combined selection power of the two markers was significant (P < 0.025, odds ratio 4.3, 95% CI 1.2-15.6). CONCLUSION: Using these markers it may be possible to select about 80% of all cases of invasive breast cancer in a high risk group comprising only 49% of the female population. This could be of importance for mammography screening; rather than unselectively screening all women in a given age bracket, it might be preferable selectively to screen only the high risk group.

Adult↗

[Mammographic screening for breast cancer--a cost-benefit analysis].

A cost-benefit analysis of the Swedish model for screening for neoplasma malignum mammae revealed scientific shortcomings in the basis for decision. It was not possible to determine whether the screening model involved a net loss or a net profit for the individual woman. Since false confidence seems to increase the mortality in breast cancer a new dimension was introduced, a sensitivity index as an expression of revealed fractions of the incidence in the participant population. This sensitivity index estimated some two thirds of the malignant neoplasms which are normally diagnosed in a two year period.

Breast Neoplasms↗

[EEG in general practice to demonstrate primary intracranial tumors. Field of applications and limitations].

In Denmark, the annual death rate due to primary intracranial tumours is 320, an unsatisfactory result of treatment that stresses the need of earlier diagnosis. This entails investigation on a wide range of indications. In a population with a low prevalence of a given disease, but with a high prevalence symptom which might be due to the disease in question, is required a highly accurate diagnostic test. Is EEG sufficiently reliable?

Brain Neoplasms↗