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Biomedical subjects

G G Hallock

Publications and source records attributed to G G Hallock.

At least 163 records · Page 9Linked to original sources
PubMed1988

Analysis of collagen content in the fetal wound.

The absence of apparent scar formation following the creation of surgical wounds in utero appears to be a phenomenon peculiarly privileged as a sequela of fetal wound healing. Little information exists to explain this disparity from our knowledge of adult wound healing. Therefore, following creation of surgical wounds in fetal rats, at different intervals the healing wounds were harvested and analyzed for collagen content and types. The average proportion of type III collagen was elevated in normal (26.5%) as well as wounded fetal skin (33.8%) when compared with normal levels for the adult (15%). The total collagen content was markedly diminished in the fetal wound. Although embryonal collagen synthesis apparently does exist in fetal reparative processes, the relationship to the lack of gross scarring remains undetermined.

Animals↗
PubMed1988

Immediate reconstruction of the auricle using the amputated cartilage and the temporoparietal fascia.

Successful restoration of the auricle following amputation using microsurgical techniques for reimplantation remains the best reconstructive alternative. In many cases of partial amputation, however, this option may not be technically feasible. Deepithelialization of the amputated part followed by coverage of the ear cartilage using an ipsilateral temporoparietal fascia turn-down flap may allow a single-stage salvage procedure that provides an acceptable final result.

Adolescent↗
PubMed1988

Venous outflow simplified by the cephalic vein loop.

Long vein loops derived from the major upper extremity superficial veins may be accessed for venous outflow in difficult cases of trunk, arm, or head and neck free tissue transfers when local possibilities have proved inadequate. This technique may negate the need for an interposition vein graft to a deep venous system, reduce the number of microanastomoses required, and allow an easy end-to-end anastomosis to a large caliber vessel. The cephalic vein loop would be the most versatile option because a great length can be achieved with minimal dissection.

Anastomosis, Surgical↗
PubMed1988

Refinement of the radial forearm flap donor site using skin expansion.

The radial forearm flap has proven to be versatile for free vascularized composite tissue transfers as well as for ipsilateral upper extremity reconstructions that require no microsurgical expertise. The most common objection to this otherwise advantageous donor area has been the subsequent nonaesthetic donor-site deformity. In addition, skin grafts frequently fail over the flexor carpi radialis tendon leading to chronic skin breakdown or at best tendon adhesions. Both these concerns may be ameliorated by means of tissue expansion of the remaining dorsal forearm skin to then allow removal of the skin-grafted portion of the donor site. These problems should be anticipated at the time of initial flap elevation so that the same incisions can be used for immediate placement of expanders.

Adult↗
PubMed1988

Puncture threshold prior to leakage from tissue expander reservoirs.

An ex vivo study was devised to ascertain the maximum number of needle punctures possible prior to onset of leakage from remote-type tissue expansion reservoirs. At least 10 standard valves obtained from all major manufacturers were analyzed using various needle gauges. An 18-gauge beveled needle was determined to be the maximum size that could be safely employed for all vendors within a usual course for tissue expansion. No significant difference was found in comparison of Dacron-reinforced versus plain silicone membrane-type valves.

Equipment Failure↗
PubMed1988

Type I and type III collagen content of healing wounds in fetal and adult rats.

Full-thickness, dermal wounds were surgically created on the dorsa of fetal rats on the 17th day of gestation. The granulation tissue which developed after 2 days (19 days of gestation) was harvested from six to nine animals and pooled and the collagen was extracted with 0.5 M acetic acid and acetic acid plus pepsin. The ratio of type III:type I collagen was estimated from densitometer scans of electrophoretically separated alpha-chains. Full-thickness (to fascia depth) wounds were also produced on the dorsa of adult rats and granulation tissue which had developed for different periods of time up to 30 days was excised. Relative proportions of type III and type I collagen were assessed in normal and granulation tissues taken from the adult rats. Both fetal and adult granulation tissues have elevated type III collagen content but normal fetal tissue has a much higher content of type III than does normal adult tissue.

Animals↗
PubMed1987

An extended latissimus dorsi "non-free" flap.

A case is reported in which perfusion of a latissimus dorsi musculocutaneous flap was maintained through its secondary blood supply during transfer to a sacral defect, while its thoracodorsal pedicle was being lengthened by saphenous vein grafts. The secondary blood supply was divided only when the microvascular anastomoses were seen to be functioning so this flap was never a truly "free" flap.

Back↗
PubMed1987

The stair-step flap for nasal reconstruction.

The stair-step nasal flap, which was originally designed to allow re-creation of the alar rim, has proved to be equally versatile for reconstruction of many other soft tissue defects of the nose. When a skin graft is unwarranted, this is a simple method for local flap transposition that minimizes any aesthetic deformity while allowing primary donor site closure. It is best suited for small or moderate sized defects of the lower and middle thirds of the nose.

Humans↗
PubMed1987

Tissue expansion techniques in burn reconstruction.

The functional or aesthetic burn deformity invariably is the consequence of a local skin shortage. The ideal solution would be replacement with new normal tissues, and these can now be created via an adaptation of the natural phenomenon of tissue expansion. Representative examples of hypertrophic scars, skin grafts, and in particular burn alopecia are presented to demonstrate the superior improvements previously not possible with conventional techniques. The concept of tissue expansion deserves an important place in secondary burn reconstruction.

Adolescent↗
PubMed1987

Skin deepithelialization using the carbon dioxide laser.

Skin deepithelialization is an integral part of many reconstructive procedures, but it can be a tedious and time-consuming ordeal when using conventional techniques. The carbon dioxide laser has been used in rats to facilitate skin deepithelialization with no adverse effect on the expected wound healing. These findings have been extrapolated for clinical applications in allowing rapid creation of the dermal pedicle required for mammaplasty.

Animals↗
PubMed1987

Suction cannula assisted placement of traction sutures.

Many reconstructive techniques require placement of autogenous tissues or temporary implants into large subcutaneous cavities. This procedure may be facilitated by using traction sutures for their insertion. The blunt suction lipectomy cannula in turn can simplify this tedious step by providing a means to pass these sutures over long distances. The technique for this simple and time-saving procedure is described.

Humans↗
PubMed1987

Suction extraction of lipomas.

With the use of suction-assisted lipectomy techniques in treatment of lipomas, the length and number of surgical scars may be minimized. The procedure is reviewed and several clinical applications are presented. Because no long-term recurrence rates are known, caution must be exercised in recommending this procedure to the patient.

Adipose Tissue↗
PubMed1987

Maximum overinflation of tissue expanders.

An ex vivo study was undertaken to document the maximum possible overinflation of tissue expanders with a comparison of all major manufacturers. Ten standard round implants from each vendor were expanded. Mean overinflation varied from 33 to 99 times stated capacity, with a range from 16 to 157 times this volume. The mechanism of failure in 93 percent of implants was envelope rupture. Overexpansion appears safe without risk of implant failure at least to 15 times vendors' stated maximum volume.

Breast↗
PubMed1987

Simultaneous bilateral foot reconstruction using a single radial forearm flap.

The radial forearm septocutaneous flap is an excellent source of thin tissue with an anatomically consistent network of large vessels that simplify microsurgical transfer. It may be divided into multiple flaps leaving a single donor-site defect. The clinical usefulness of this concept is demonstrated in a single case in which simultaneous coverage of electrical burns of both feet was required.

Burns, Electric↗
PubMed1987

Extremity tissue expansion.

The gradual mechanical distention of tissues in the extremities using inflatable balloons allows elimination of local defects or expansion of known extremity donor sites to facilitate other reconstructive requirements. Complication rate are higher for extremity tissue expansion, and proper caution must be adopted if this concept is to be valuable for applications in the extremities.

Adolescent↗