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Biomedical subjects

G G Karmazanovskiĭ

Publications and source records attributed to G G Karmazanovskiĭ.

At least 19 recordsLinked to original sources

[Virtual surgeries based on spiral computed tomography].

Experience of spiral computed tomography with bolus contrast enhancement and subsequent 3D-reconstruction of picture for virtual modeling of surgeries is presented. The method was used in 204 patients with tumors and diseases of the liver, pancreas, spleen, kidneys, adrenal glands, parapapillary diverticula of the duodenum, coarctations and aneurysms of aorta, extraorganic tumors of the retroperitoneal cavity and neck. Coincidence of virtual and real types of surgeries reached 75-92.8% depending on the disease and clinical situation. Perspectives of 3D-reconstruction for evaluation of normal and pathologic anatomic features in an individual patient, choice of an optimal surgical variant, prognosis of possible complications and their prophylaxis are demonstrated. Integration of surgeon's and radiologist's thinking is very important for correct diagnosis and surgical policy.

Adolescent↗

[Videothoracoscopy in diagnosis and treatment of small peripheral pulmonary masses].

This study was devoted to examination of efficacy of modern methods of diagnosis and surgical treatment of patients with small peripheral pulmonary masses (SPPM) with the use of videothoracoscopy. The results of examination and treatment of 126 patients with SPPM (80 patients underwent videothoracoscopy) were analysed. This study demonstrated high-quality of modern complex of clinicoradiological investigations for diagnosis of SPPM. The reliability of the complex is 91%. The necessity of immediate elective operation of the patients with SPPM is shown for verification of the process and adequate surgery. Videothoracoscopic surgery is effective method of treatment in patients with SPPM.

Diagnosis, Differential↗

[Differential diagnosis of pancreatic head cancer].

The results of clinical, instrumental and laboratory examinations were analyzed for 99 patients. 59 of them had pancreatic head cancer, 40--chronic pseudotumorous pancreatitis. The importance of complex ultrasonic diagnosis in detection of pancreatic diseases (98%), in true diagnosis of unresectable tumors (96.7%), and also in determination of bile ducts lesion level in obstructive jaundice is shown. It was revealed that spiral computed tomography (SCT) had an advantage over computed tomography in diagnosis of pancreatic tumors and in assessment of their resectability. Sensitivity of combined use of US, SCT and tumor marker CA 19-9 in pancreatic cancer diagnosis increases to 95.2%. High diagnostic value of laparoscopy with laparoscopic ultrasonic examination as a method of final assessment of tumor resectability is shown.

Biomarkers, Tumor↗

[Clinical features, diagnosis and treatment of benign nonepithelial tumors of stomach].

The results of treatment of 24 patients with benign nonepithelial tumors of the stomach (BNTS) are presented. The majority of the tumors were leiomyomas (42%). The preoperative diagnostic algorithm included x-ray examination of upper gastrointestinal tract, endoscopic examination with histologic study (biopsy), ultrasound examination and CT. The best results were obtained in CT. The operation of choice in BNTS are wedge-resection of the stomach and enucleation (78.3% of patients).

Adolescent↗

[Spiral computer tomography in diagnosis of hepatic diseases].

Spiral computer tomography (SCT) is a new method of computer tomography by which, in contrast to conventional CT, the information about absorptional capacity of tissues is obtained without omission of images which makes it possible to build MPR and 3D of a very high quality. 205 patients with diseases of hepatopancreatoduodenal area were examined, in 189 patients the diagnosis being verified. Optimal technique of intravenous bolus contrasting in SCT was developed. Using various time interval between the start of the scanning and the beginning of infusion of contrast media, it is possible to obtain primary image of the arteries (arterial phase of contrasting, time of delay 18-25 sec.), the picture of veins and the image of saturation of hepatic parenchyma--(venous return phase, time of delay 60-80 sec.), to reveal characteristics of contrasting of the liver masses during delay (8-15 min) phase. The largest quantity of masses are revealed in arterial phase of contrasting. Specific features of contrasting in hemangiomas and malignant tumors of the liver has been revealed. Hemangiomas absorb contrast medium already at the early phase as hypercontrasted lacunas in an outlying areas, at a late phase they are hyperdenced in relation to hepatic parenchyma. Primary and metastatic tumors of the liver accumulate contrast medium in an early phase along the whole area and quickly lose contrast medium during parenchymal phase. The method of contrast intensification enables evaluation of interrelation between tumor and vessels, to determine passage of hepatic arteries and branches of portal and hepatic veins, to visualise choledochal duct, to determine the distance between hepatic and tumor surface, and to produce these data as a view of multiplanar and three-dimensional image (reconstruction). The effectiveness of obtained reconstructions in planning of the extent of surgical intervention is demonstrated.

Contrast Media↗

[Roentgenological examination of stomach after pancreatoduodenectomy].

High frequency of complications after pancreatoduodenal resections dictates the necessity to study causes of their origin. This paper provides the results of roentgenologic examinations in early and late postoperative periods in 24 patients who underwent classic pancreatoduodenal resection by Whipple and in 23 patients after pylorus saving pancreatoduodenal resection--operation by Traverzo-Longmire. Conventional method of roentgenologic examination of the operated stomach was used. In early postoperative period disturbances of motor-evacuatory function of upper parts of gastrointestinal tract were revealed in 50% of patients in any modification of pancreatoduodenal resection. In most cases slowering down of the evacuation up to complete gastrostasis was observed. But in long-term follow-up functional results after pancreatoduodenal resection according to x-ray examination data were much better after operation by Traverzo-Longmire (75% patients) than after classic version by Whipple (37% patients). Thus, the results of roentgenologic examination showed that pylorus saving version of pancreatoduodenal resection provides optimal conditions for normal activities of the saved organ.

Barium Sulfate↗

[Assessment of the results of surgical treatment of lymphedema based on computerized tomography].

The possibilities of computed tomographic appraisal of the qualitative and quantitative characteristics of the soft tissues in lymphedema of the lower limbs were studied in comparison with the results of pre- and postoperative examination of 21 out of 86 patients with Stage II-IV lymphedema. There were 4 males and 17 females, whose ages ranged from 16 to 41 years. In postoperative periods of 2 weeks to 6.5 years 45 computed tomographic studies were conducted. It was shown that computed tomography is an objective basis for appraising the qualitative and quantitative changes in the soft tissues of the limbs in follow-up patients with lymphedema after creation of lymphovenous anastomoses. The examination confirms objectively functioning of the lymphovenous anastomoses after disappearance of supra- and subfascial edema and diminution and even normalization of the thickness of the subcutaneous fat.

Adolescent↗

[Computed tomography in the comprehensive radiologic diagnosis of chronic osteomyelitis of the lower extremities and pelvis].

The role of computed tomography in multimodality radiation diagnosis was assessed in the treatment of chronic osteomyelitis of the lower extremity and pelvis in 218 patients (128 with posttraumatic osteomyelitis, 46 with hematogenic osteomyelitis of long bones, and 19 with chronic pelvic osteomyelitis) aged 16-78 years. Computed tomography was used to specify the symptomatology of chronic osteomyelitis, to define indications for radical surgical treatment. The soft tissues of the shin were studied in patients with chronic osteomyelitis versus lymphedema in 103 patients, post-thrombophlebitic syndrome in 17, acute wound infection in 9. The symptomatology of osseous regenerate in distraction osteosynthesis was studied (120 computed tomograms). It has been indicated that computed tomography is effective in studying the chronic osteomyelitis-inflicted extremity and pelvis in the pre- and postoperative periods.

Adolescent↗

[Computed tomography in the diagnosis of suppurative sacroiliitis in chronic pelvic osteomyelitis].

The object of the investigation was to study the possibilities of CT diagnosis of purulent sacroiliitis and evaluate the effect of its results on the choice of the volume of the surgical intervention and the operative tactics. The pelvis was examined in 15 patients with chronic hematogenic osteomyelitis of the pelvic bones; clinical signs of involvement of the sacroiliac articulation were encountered in 11 of them. There were 5 men and 6 women whose ages ranged from 18 to 62 years. The results of examination of the sacroiliac articulation were appraised in its upper, middle, and lower levels. The computed-tomographic signs of purulent sacroiliitis are shown. It was established that computed tomography is an effective modern method of spot-film examination of the sacroiliac articulations for which the patient does not have to be specially prepared. It yields objective information on the condition of the pelvic bones, including the sacroiliac articulation. The method makes it possible to determine the indications for the operation, choose the best operative approach in each specific case, and to predict beforehand the volume of the operative intervention.

Adolescent↗

[Cystic tumors of the pancreas].

Thirty-three patients were operated on for cystic tumors of the pancreas at the Vishnevsky Institute of Surgery in 1980-90. Cystadenoma of the pancreas was found in 16 (48.5%) of them and cystadenocarcinoma in 15 (45.5%). Fifteen (45.5%) patients had been previously operated on in different institutions presumably for a "cyst" of the pancreas, 6 of them repeatedly; the tumor recurred rapidly in all of them. In the Institute 30 patients underwent radical operations: 30 distal resection of the pancreas and 5 pancreatoduodenal resection. Diagnostic and palliative manipulations were performed on 3 patients. Postoperative lethality was 9.1% (3 patients). Postoperative follow-up periods lasted from 12 months to 9 years. Dissemination of the tumor occurred in 2 patients two years after the operation. The remaining 25 patients are alive and capable of working.

Adult↗

[Computed tomography in the diagnosis and selection of surgical treatment for angiodysplasia].

Fifty-five patients (31 males and 24 females) with various localization of angiodysplasia (the region of the pelvis and pelvic organs, trunk, head and face, and the limbs) were examined. Comparison of angiography and computed tomography of the 55 patients showed that only 8 cases (15%) of arteriovenous angiodysplasia had vascular changes characteristic of angiodysplasia in arteriography. Changes of vessels were not revealed by phlebography, whereas computed tomography yielded a positive result in 54 cases. Thus, computed tomography, even without the use of contrast intensification, is the main method for the diagnosis of venous-cavernous angiomatosis of organs and deeply situated tissues. Computed tomography makes it possible to determine the tactic and volume of operative treatment and to control the efficacy of the applied treatment.

Adolescent↗

[Radiographic endovascular correction of hyperaldosteronism in patients with arterial hypertension].

The authors describe a new method of X-ray endovascular destruction of the adrenal in patients with arterial hypertension and hyperaldosteronism. Destruction of the adrenal is accomplished by acute occlusion of its venous channel by introduction of a 3% thrombovar solution through a catheter installed in the central vein of the suprarenal gland. This method was applied in 22 patients with arterial hypertension; essential hypertension with secondary hyperaldosteronism was found in 18 of them, renoparenchymatous hypertension in 2, aldosteroma of the left adrenal in one, and Itsenko-Cushing's disease in one patient. Acute occlusion of the adrenal venous channel was achieved in 20 patients. The intervention normalized blood pressure in 16 and reduced it significantly in 4 patients.

Adrenal Glands↗