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Biomedical subjects

G G Lemire

Publications and source records attributed to G G Lemire.

12 recordsLinked to original sources
PubMed1983

Prolene sutures are not a significant factor in anastomotic false aneurysms.

Anastomotic false aneurysms have been a significant complication in vascular surgery, and the sutures used have been a major cause. Monofilament sutures have been indicated as contributing to the formation of false aneurysm. However, most of the monofilament sutures operative in the formation of false aneurysms have been made of polyethylene. Polypropylene, although significantly different from polyethylene, has been associated and possibly confused with it. Very few anastomotic aneurysms have resulted from breakage of polypropylene sutures. In this series of 2,400 vascular anastomoses in which polypropylene sutures were used, there were 10 false aneurysms; however, only one resulted from suture failure. In that patient, two Dacron grafts were anastomosed with 5-0 polypropylene suture. Polypropylene is a satisfactory and safe suture material for vascular anastomoses. It does not fragment or break easily when properly handled, and therefore is not a principal cause of false aneurysms.

Aneurysm↗
PubMed1980

Prevention of high flow problems of arteriovenous grafts. Development of a new tapered graft.

Blood flow of 2 to 3 liters/min was measured in polytetrafluoroethylene (PTFE) arteriovenous dialysis grafts. The flow studies were done at the time of graft banding for high output cardiac failure or peripheral steal. Routine tapering of the arterial end of these grafts to a diameter of less than 5 mm has virtually eliminated this problem. Prototype tapered PTFE grafts supplied by the graft manufacturers have been very acceptable during 12 months of use.

Blood Flow Velocity↗
PubMed1978

Alterations in red cell metabolism during and following cardiac bypass surgery.

Reduced concentrations of red cell organic phosphates and increased hemoglobin--oxygen affinity have been reported during and following cardiac bypass surgery. Some have related these changes to low concentrations of ATP and 2,3-diphosphoglycerate (DPG) in stored blood while others have related them to use of the pump oxygenator. There was a 10% decrease in DPG concentration in seven dogs on cardiac bypass although the animals received no transfusions. In 16 patients who received 0 to 7 units of blood during cardiac bypass there was a decrease of 10% in the red cell DPG concentration from the preoperative value, but it did not relate to the concentration of DPG in the transfused blood bags. The magnitude of the decrease was not sufficient to impair oxygen delivery severely. The results suggest that a re-evaluation of indications for the use of fresh red cells in cardiac surgery is necessary.

Adenosine Triphosphate↗
PubMed1977

Angiography: an essential diagnostic aid in asymptomatic aortic aneurysm?

Aortography is a highly desirable diagnostic procedure for evaluating clinically diagnosed abdominal aortic aneurysm. In a retrospective study of 83 patients with such aneurysms, routine angiographic investigation changed the course of management in 17. The morbidity associated with angiography in the investigation of abdominal aortic aneurysm has been minimal. In this situation angiography provides more information than ultrasonography and therefore should be used routinely.

Aged↗
PubMed1977

Dysphagia lusoria: anterior approach for definitive treatment.

An aberrant right subclavian artery causing symptoms is rare in adults. Several surgical approaches have been advocated. On the basis of results obtained in two patients, the authors recommended an anterior approach, either a transternal bilateral thoracotomy or a median sternotomy, that affords excellent exposure for flush ligation and division of the right subclavian artery at the aorta, and reconstruction on the ascending aorta.

Adult↗
PubMed1975

Pacemaker infections: a 12-year review.

In a 12-year period, 546 pacemaker-related operations were complicated by 23 infections (infection rate, 4.2%). Most of these infections were treated successfully, but two cases of infection were fatal. The most frequently encountered organism was Staphylococcus epidermidis. In 14 cases, infection occurred despite the preoperative administration of cloxacillin to which the organism was sensitive in 13 of the cases. The skin flora constitute the most likely source of contamination. The ideal treatment consists of removal of all foreign material and replacement with a new pacing system by an alternative route.

Bacterial Infections↗
PubMed1974

A study of human cardiac allograft in a patient with four-year survival.

A report is presented of a patient surviving four years with a human cardiac allograft. The allograft arteries showed marked graft arteriosclerosis with intimal fibrocellular proliferation. The arteriosclerotic lesions occurring in the larger epicardial vessels were strikingly similar to spontaneous atherosclerosis. The relationship of the long-term survival to the use of a permanent transvenous pacemaker and of the development of severe vascular lesions to acute rejection and hyperlipemia are discussed.

Aorta↗