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Biomedical subjects

G G Wells

Publications and source records attributed to G G Wells.

6 recordsLinked to original sources
PubMed1981

Acute behavioral effects of styrene exposure: a further analysis.

Studies were carried out on two groups to styrene-based resin. Early morning urinary mandelic acid concentrations after two days without exposure correlated with reaction time measured on arrival at work. Men were found to differ considerably in their rate of clearance of mandelic acid-those with slow reaction times. After some months at reduced exposure, a small group of men with previously high mandelic acid concentrations has speeded up on the reaction time task.

Adult↗
PubMed1981

Some observations on workers exposed to methylene chloride.

An excess of self-reported neurological symptoms was found when a group of 46 men exposed to methylene chloride at concentrations below 100 ppm was compared with a non-exposed referent group. A follow-up study was then carried out to see whether there was any evidence of neuropsychological damage in the exposed men. Twenty-nine of the original group participated in this study. Age-matched controls controls were selected from among men working on a similar process but with no exposure to solvents. Each man in the study had a clinical examination; motor conduction velocities were measured in the ulnar and median nerves; an ECG was taken and a psychological test battery was designed to detect minimal brain damage was administered. No evidence was found of long-term damage that could be attributed to exposure to methylene chloride.

Adult↗
PubMed1980

An investigation of the acute behavioural effects of styrene on factory workers.

A group of men exposed to styrene in a factory building glass-fibre boats performed a series of behavioural tests at the beginning and end of their shift, and the results were compared with those of a referent group from the same factory. Changes in mood were noted in both groups of workers but were greater in the exposed men; moreover, the change in mood was correlated with blood styrene concentration. In the styrene workers the morning reaction time was slower than that for the referents. During the day the reaction time of the men with low blood styrene concentration (less than or equal to 5.4 mumol/l) speeded up and in the afternoon was similar to that of the referents; the reaction time for the men with high blood styrene concentration (greater than or equal to 5.5 mumol/l) was unchanged. Data taken from a questionnaire indicated that the men exposed were much more likely than was the referent group to report feeling unduly tired. They also reported feeling more tired on Friday night than Monday night, suggesting that the styrene might have a cumulative effect through the week.

Behavior↗