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Biomedical subjects

G Günther

Publications and source records attributed to G Günther.

At least 19 recordsLinked to original sources
PubMed1991

Septicemia in patients with hematological disorders and neutropenia. A retrospective study of causative agents and their resistance profile.

In order to identify the cause of septicemia and the resistance patterns of bacteria in Swedish patients with hematological disorders, all positive blood cultures collected at a hematological ward during 1980-1986 were evaluated retrospectively. 198 episodes of septicemia in 129 patients were recorded. 54% were males and 46% women with a median age of 67 years (range 16-88). Patients with acute leukemia (46%), lymphoma (19%) and myeloma (19%) dominated. The absolute neutrophil count (ANC) was less than 0.5 x 10(9)/l in 76% of the bacteremic episodes. A total of 253 consecutive isolates were found with 53% Gram-negatives and 47% Gram-positives. The dominating pathogens were Escherichia coli (27%), klebsiella/enterobacter (15%), pseudomonas (7%), coagulase negative staphylococci (13%), alpha-streptococci (13%), Staphylococcus aureus (10%) and anaerobes (6%). Coagulase negative staphylococci showed a significant increase in isolation rate during the study period. The majority of E. coli were resistant to ampicillin. The susceptibility of klebsiella/enterobacter to ceftazidime and cefuroxime was reduced, while no imipenem resistant strains occurred. Among coagulase negative staphylococci 61% were resistant to isoxazolylpenicillin, none to vancomycin. No dramatic changes in the etiology of septicemia or the susceptibility pattern during the study period were noticed. Coagulase negative staphylococci, S. epidermidis in particular, constitute an increasing problem among granulocytopenic patients.

Acute Disease↗
PubMed1979

[Catamnestic studies of normally intelligent encephalopathy patients among children and adults].

Our studies show that the special features in the psychic development of encephalopaths showing normal intelligence consist in delayed motor, intellectual and educational progress. While motor retardation is reduced with age, as a result of such factors as rhythmical and psychomotor musico-therapy, individual intelligence test results drop more frequently at school age. The drop is less marked in students attending special classes, although they go back to their original schools after grade 4. The trend toward deterioration in intellectual development is reduced with age, i.e. when educational progress as encouraged by society, slows down. Despite their normal performance with regard to intelligence these students markedly lag behind their healthy contemporaries as far as performance at school is concerned.

Adolescent↗