Biomedical subjects

G Gabriele

Publications and source records attributed to G Gabriele.

6 recordsLinked to original sources

PubMed2003

Retinotopic modulation of space misrepresentation in unilateral neglect: evidence from quadrantanopia.

A patient with right sided brain damage suffered contralesional neglect, inferior quadrantanopia (with 0 degrees sparing in the left eye and 13 degrees sparing in the right), and a visual field restriction (to 15 degrees ) in the upper contralesional quadrant of the left eye. In binocular vision, the patient showed underestimation of the horizontal size of contralesional line segments unless cued to localise their end points. When asked to reproduce, in monocular vision, 10 degrees and 20 degrees distances between two attentionally cued end points lying on the frontal vertical plane, the patient showed relative contralesional overextension and ipselesional underextension along the directions falling within the blind sectors of the neglected space. No asymmetry was present along the directions falling within the seeing sectors of the same space. These findings suggest precise retinotopic modulation of space misrepresentation in unilateral neglect.

Aged↗

PubMed1998

[Border-line headache].

BACKGROUND: The authors, after a thorough review of the literature, and on the basis of personal clinical experience, propose a new approach to the resolution of pain symptomology of border-line cephalea (a pathology as much debated as it is diffused). Therefore, they suggest an interdisciplinary therapeutic protocol. METHODS: After a careful examination of the triggering causes of pain symptomology, they examined 24 patients. They were examined at the out-patient clinic of the Institute of Oral and Maxillo-Facial Surgery, Second University of Study of Naples. With the aid of a questionnaire they gathered the anamnestic data; and, after an objective clinical examination the patients were submitted to neurologic examination. Working together with a neurologist, the patients were firstly examined individually and then, based upon differential differences in symptomatology, they were subdivided into three experimental groups in order to facilitate the association of the therapy to the groups and make follow-up easier. RESULTS: The results were encouraging and demonstrated the necessity to study the patients affected by this type of pathology with a pluridisciplinary approach: gnatologic, psychologic, and neurologic. CONCLUSIONS. Therefore, the importance, if not the necessity, of an interdisciplinary approach is underlined. The authors want to emphasize the importance of not focusing on only one aspect of this kind of pathology, but it must be considered in a wider field including more than one discipline.

Female↗

PubMed1991

[Phakomatosis in childhood. Clinical and instrumental observations of 11 cases].

Taking the institution of the Italian Neuroectodermosis Register (Fois, April 1987) as a starting point, the Authors reviewed their own case-records, including six cases of neurofibromatosis and five cases of tuberous sclerosis, observed during the period 1982/88, and stress the need for early diagnosis (unfortunately often neglected), indispensable both for an effective prevention of any pathological involvement and for precise genetic counselling, susceptible of further improvements thanks to more and more advanced diagnostic techniques.

Adolescent↗

PubMed1981

Regional blood flows in newborn lambs during endotracheal continuous airway pressure and continuous negative pressure breathing.

Cardiovascular changes resulting from continuous distending alveolar pressure during endotracheal intubation (CPAP) and continuous negative pressure (CNP) were studied in two groups of healthy newborn lambs at 6 and 11 mm Hg and -6 and -11 mm Hg, respectively. Heart rate, left ventricular pressure, and arterial blood gases were unchanged in each group. Cardiac output decreased 16 and 15% at 6 and 11 mm Hg CPAP (P less than 0.05), respectively, whereas a fall of 9% occurred at both -6 and -11 mm Hg CNP (P greater than 0.05). Central venous pressure (mm Hg) rose from a control value of 7.0 +/- 1.4 (mean +/- S.E.) to 11 +/- 3.1 and 12 +/- 2.7 at 6 and 11 mm Hg CPAP (P less than 0.025), respectively, and decreased from a control of 7.7 +/- 0.7 to 5.8 +/- 0.5 at -6 mm Hg CNP and 4.8 +/- 1.3 at -11 mm Hg CNP (P less than 0.05). Jugular venous pressure also rose progressively with increasing CPAP (P less than 0.05), but was unchanged during CNP. Regional blood flow to the liver fell at both 6 and 11 mm Hg CPAP, whereas renal and gastrointestinal blood flows showed a tendency to decrease at 11 mm Hg CPAP. The removal of CPAP resulted in a prompt return of venous pressure, cardiac output, and regional blood flows to control values. Reductions in blood flows to the gastrointestinal tract at -6 mm Hg CNP and spleen at -11 mm Hg CNP were observed; blood flows returned toward control values when CNP was removed.

Animals↗

PubMed1977

Continuous airway pressure breathing with the head-box in the newborn lamb: effects of regional blood flows.

Continuous airway pressure delivered by a head-box is an accepted means of treating clinical hyaline membrane disease. To investigate hemodynamic alterations resulting from its use, eight newborn lambs, 1 to 6 days of age, were studied at 6 and 11 mm Hg of positive pressure, while spontaneoulsy breathing room air. Organ blood flows and cardiac output were measured with 25 micron-diameter radioactive microspheres. Heart rate, left ventricular pressure, and arterial blood gases did not change during the study. Jugular venous pressures increased from 6.4 mm Hg to 18.6 and 24.2 mm Hg at 6 and 11 mm Hg, respectively (P less than .005). Cardiac output decreased approximately 20% at either intrachamber pressure setting. Renal blood flow fell 21% at 11 mm Hg. No significant changes in blood flow were found in the brain, gastrointestinal tract, spleen, heart, or liver when compared to control flows. Of particular interest was the finding of a 28% reduction in ocular blood flow at 6 mm Hg and 52% at 11 mm Hg. From these results, we conclude that substantial cardiovascular alterations may occur during the application of head-box continuous airway pressure breathing, including a significant reduction in ocular blood flow.

Animals↗

PubMedDate not supplied

[Probable ADH inappropriate secretion syndrome in varicella].

Varicella (chickenpox) is sometimes associated with serious complications characterized bp changeable frequency in different ages. We describe a case of varicella with contemporary presence of several complications: serious impetigo , conjunctivitis, pneumonia, hepato-encephalic disease (probable Reye syndrome). This case is interesting because after adequate rehydration and normalization of electrolytes we registered a remarkable fall of plasmatic sodium and chloride as a result of hemodilution probably due to a syndrome of inappropriate secretion of antidiuretic hormone, confirmed by values of plasmatic and urinary osmolarity and of urinary electrolytes.

Chickenpox↗