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Biomedical subjects

G Gallina

Publications and source records attributed to G Gallina.

At least 19 recordsLinked to original sources
PubMed1989

Lack of correlation between HLA-B35 resistance against herpes labialis and antibody titers to HSV-1.

To investigate whether genetic factors linked to the human leukocyte antigens (HLA) might influence individual resistance to recurrent herpes labialis (RHL), we studied the frequencies of HLA-A, -B, and -C antigens in a sample of Sicilian population. The frequency of HLA-B35 was significantly decreased in the patient group (p corrected = 0.018). Consequently, the relative risk of development of RHL in a subject positive for HLA-B35 was 20 times smaller than in a subject who does not bear B35. Furthermore, a study was made of the possible relationship between the presence of HLA-B35 antigen and antibody titers to herpes simplex virus type 1 (HSV-1) in 62 persons affected or not by RHL. Significantly elevated titers to HSV-1 were found in the diseased group (p less than 0.001), but the geometric mean of antibody titers in HLA-B35 positive subjects was not different from that of B35 negative subjects either of RHL-affected or in healthy persons. These data are in a good agreement with the hypothesis that humoral immune responses play a marginal role in the protection from HSV-1 recurrences.

Adolescent↗
PubMed1987

MHC-linked genetic factors (HLA-B35) influencing recurrent circumoral herpetic lesions.

The frequencies of HLA-A, B, C, DR, and DQ lymphocyte alloantigens were determined in 31 Sicilian patients with recurrent herpetic lesions (RHL) and compared to frequencies observed in normal individuals. A significant negative association was found for HLA-B35 (pc = 0.049). The relationships between HLA and immune responses to viral infections are discussed in light of the results revealed by the present investigation suggesting that HLA-linked genetic factors may play a role in the pathogenesis of RHL. The results seem to indicate that genes in the major histocompatibility complex (MHC) are influential against developing RHL.

Adult↗
PubMed1985

HLA-A, B, C, DR, MT, and MB antigens in recurrent aphthous stomatitis.

In this report we have investigated the frequencies of HLA-A, B, C, DR, MT, and MB markers in 26 Sicilian subjects affected by recurrent aphthous stomatitis (RAS) and in 84 healthy controls. Our data show that the frequency of HLA-DR7 antigen is significantly increased in RAS-affected persons (61.5% versus 21.4%; pc less than 0.0025), whereas the B5 antigen frequency is decreased significantly (absent in patients versus 27.3% in controls; pc = 0.04). Thus, present results suggest that HLA-linked genetic factors may play a role in the development of RAS.

Adult↗
PubMed1984

[Activation of the alternative complement pathway by Newcastle disease virus. I) Effect of the virus on the complement system in vivo and in vitro].

The authors have studied the effect of the paramyxovirus of Newcastle disease on the complement system in the mouse. The results obtained show that NDV activate both in vivo and in vitro the alternative complement pathway, suggesting that the intervention of complement system during viral infections represents a general biological phenomenon.

Animals↗
PubMedDate not supplied

[S.E.M. analysis of composite resin surfaces applied to chemically and chemo-mechanically treated dentin].

The authors evaluated, at scanning electron microscope (S.E.M.), the morphological aspects of composite resin surfaces applied on dentin subjected, "in vitro", to chemical or chemo-mechanical treatments. S.E.M. photographs of dentinal surfaces of composite, applied on dentin treated with acid agents or Caridex, showed extensive penetration of resin tags into dentinal tubules and their deep adaptation to rough and winding dentinal surfaces. The obtained results have been evaluated in the light of recent advances in biocompatibility and long-term stability of composite fillings, in particular, to setting up new materials and methods in cavities preparation and treatment.

Acid Etching, Dental↗
PubMedDate not supplied

[Scanning electron microscopy evaluation of wear of turbine rotary instruments].

A wear test was conducted to evaluate carbide and diamond dental burs, in air turbines at 400,000 r.p.m., by using a dentine-enamel substrate. There is less variability within each bur type. All of the burs showed a decreased ability to make a standard cut with succeeding trials. Generally, a linear dulling rate was observed with a progressive reduction of cutting effectiveness, except for middle grain burs, that showed better characteristics among tested burs.

Dental High-Speed Equipment↗
PubMedDate not supplied

[Plasmacellular neoplasms of the head and neck: clinical status and personal experience].

In this review, the authors examine the diagnostic, prognostic and therapeutic advances in clinical management of Solitary Plasmacytoma of bone, Extramedullary Plasmacytoma and their relationship to multiple myeloma. The clinical differences among these tumors are the subject of continued studies. Oral symptoms and signs of the neoplasias are relatively common. The literature is reviewed with respect to the prevalence of oral and maxillofacial manifestations and the presence of such manifestations as the first sign and/or symptom of disease. The case of a young adult patient, with a kappa-light-chain positive extramedullary plasmacytoma of the maxillary sinus is presented. The reported case illustrates the necessity of a multidisciplinary approach using relevant immuno-hematologic, radiographic and histologic investigations in the differential diagnosis of these tumors. Factors influencing the prognosis of these neoplastic lesions are also discussed.

Adult↗
PubMedDate not supplied

[Recent advances in diagnosis of Sjogren's syndrome].

In this paper the authors review the classification and the clinical features of primary and secondary Sjogren's syndrome. Particular attention in focused on differential diagnosis, on clinical examination of the patients with chronic xerostomia and on its functional and pathological sequelae: rampant dental caries and oral candidiasis. Advanced in diagnostic procedures are described: salivary flow rate, salivary gland scintigraphy, parotid and submandibular scialography, Schirmer's test, Rose Bengal staining, minor salivary gland biopsy and serum immunological examinations. The relationships between scintigraphic and histologic result are discussed. The clinical features and the course of the disease provide further insight into the immunological pathogenesis of this syndrome.

Candidiasis, Oral↗