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Biomedical subjects

G Gaspari

Publications and source records attributed to G Gaspari.

18 recordsLinked to original sources
PubMed1998

[Urologic complications of diverticulosis of the colon].

In this paper the complications of colonic diverticulosis are reported, on the basis of two clinical cases personally observed. In the first case, a 68 year-old man, the typical symptomatology with pneumaturia, cloudy urine and watery diarrhea suggested a uro-colonic fistula, therefore a fistula between sigma and bladder, caused by a perforate diverticulum, has been diagnosed by means of cystography and barium enema. In the second case, a 64 year-old woman, the irritative symptomatology, hematuria and endoscopic picture suggested a vesical neoplasia. An accurate examination with abdominal TAC and barium enema, showed a perforate diverticulum between uterus and bladder, without affecting the bladder lumen. The surgical treatment required, in both cases, a left hemicolectomy, a minimal bladder resection in the first case, and a greater one in the second case. During the discussion, the main etiopathogenetic causes of uro-colonic fistulae together with the variants in the onset symptomatology, have been stressed.

Aged↗
PubMed1995

[A case of adrenal neoplasm].

Pheocromocytoma is a rare adrenal tumor. Generally its size is reduced and it is one of the causes of arterial hypertension. The authors present a case of giant pheocromocytoma, without arterial hypertension, and particularly they write about the used diagnostic and therapeutic management.

Adrenal Gland Neoplasms↗
PubMed1995

[Large inguino-scrotal bladder herniation].

The authors describe a case of voluminous inguinoscrotal bladder erniation. They write about the subjet with the help of the literature and above all they show the possible dangers of a vesical underestimated injury.

Hernia, Inguinal↗
PubMed1992

Best's multiple vitelliform degeneration.

Best's disease with multifocal lesions is rare. The authors describe four cases of multifocal vitelliform disease. The fluorescein angiographic features of macular and extramacular lesions are considered. Different stages of evolution may be present between central and extramacular lesions.

Adolescent↗
PubMed1987

Oral anticoagulant therapy control: evidence that INR expression improves the inter-laboratory comparability of results--the Bologna oral anticoagulant control exercise.

The aims of the present study were: 1) interlaboratory normalization of prothrombin time (PT) testing for anticoagulant therapy control through calibration of customary thromboplastins against international reference materials, and 2) "on field" validation of the advantages offered by expression of results as International Normalized Ratio (INR) as opposed to percentage activity. PT tests were carried out over 8 days on the same normal subjects (16) and patients on oral anticoagulants (48) in the 9 laboratories of the Bologna area. The use of customary thromboplastins and coagulometers was maintained in all labs throughout the study. The main results were: 1) the interlaboratory CV of the prothrombin ratios obtained for each sample with all customary thromboplastins (5 different brands) was 15%, but was reduced to levels of 5.8 to 8.9 when using constant thromboplastin brands and batches; 2) the International Sensitivity Index (ISI) values obtained in the different labs were only slightly influenced by the use of different coagulometers; 3) comparable ISI values were obtained through direct calibration with the international reference material and through intermediate calibration with a locally selected standard; 4) use of INR values instead of percentage activity greatly reduced interlaboratory variability and significantly improved uniformity of anticoagulation level measurements, thus reducing the possibility of erroneous prescriptions. The Bologna exercise is therefore of educational value for laboratory and community doctors of the area in understanding and accepting the INR system.

Administration, Oral↗
PubMed1976

[Agnogenic myeloid metaplasia (author's transl)].

The AA., present a case of "agnogenic myeloid metaplasia" (MMA). They describe the principal findings that have led to this diagnosis: Fe59-erythrocynesis, radiologic study of skeleton and cytogenetic study. Fe59-erythrocynesis have shown an hypergetting of spleen and liver and an hypogetting of skeleton. The radiography of skeleton and particularly of humerus, femur and pelvis have shown a diffuse osteosclerosis with rare osteolytic areas. The cytogenetic study have shown an alteration with C-group trisomy.

Bone and Bones↗
PubMed1975

[Waldenström's syndrome and chromosome aberrations].

The AA. present a case of Waldenström syndrome with chromosomic alterations. The cytogenetic study demonstrated that 3% of metaphases are represented by maps with 47 chromosomes for a supernumerary sub-metacentric chromosome like the A-3 group. On 12% of euploid maps they found similary the sub-metacentric chromosome a-3 group like (chromosome MG) and, at the same time, the lack of an element of the 18-group.

Antibody Formation↗
PubMedDate not supplied

Klinefelter's syndrome in nontwin brothers and maternal XX/XXX mosaicism.

A case of two nontwin brothers, 19 and 17 years old, who had both Klinefelter's syndrome with a chromosomal mosaicism 46 XY/47 XXY, is reported here. The analysis of their mother's karyotype revealed a 46 XX/47 XXX mosaicism. It is hypothesized that the presence of an extra X chromosome in all three subjects could depend on the transmission of two X chromosomes from the mother to the sons or, less likely, on an increased liability to nondisjunction of the X chromosomes during one of the early mitotic divisions in the zygotes.

Adolescent↗
PubMedDate not supplied

[Role of the markers PAP-PSA in the diagnosis of cancer of the prostate].

The Authors report their personal experience relating to diagnostic screening for prostatic carcinoma using serum assays for specific markers of this tumour: prostatic acid phosphatase (PAP) and prostatic specific antigen (PSA). They underline the importance of high serum values of these substances, especially in tumors in an advanced state, and point out that these markers can play a role both in the diagnosis and in the follow-up of prostatic carcinoma.

Acid Phosphatase↗