PubMed Health⌕ Search

Biomedical subjects

G Gauthier

Publications and source records attributed to G Gauthier.

16 recordsLinked to original sources
PubMed1992

The practice of complete denture prosthodontics by selected dental graduates.

Graduates of a dental school in the southeastern United States were surveyed for the procedures they used in practicing complete denture prosthodontics. Of the 530 graduates representing 15 graduating classes, 80% returned the questionnaires. Most respondents (94.8%) made complete dentures, but only 3.5% devoted more than 20% of their practice time to this phase of prosthodontics. In practice, the average graduate performed approximately one half of the techniques that had been judged academically to be clinically essential. Compliance decreased proportionately with the number of years in practice. Factors affecting compliance include the influence of peer practitioners and continuing education courses. The content of the predoctoral curriculum needs to be reviewed for its relevancy to continuing education and to dental practice.

Centric Relation↗
PubMed1992

[Cerebral ischemic accidents and tuberculous meningitis].

Two cases of tuberculous meningoencephalitis mimicking regressive or transient ischaemic attacks or migraine with aura are reported. The value of MRI with gadolinium in demonstrating inflammation of the leptomeninges, of transcranial Doppler sonography in detecting segmentary accelerations in the basal cerebral arteries suggestive of arteritis and of CSF examination with polymerase chain reaction (PCR) are emphasized.

Arachnoid↗
PubMed1979

Increased frequency of HLA--DRw2 and DRw3 in multiple sclerosis.

Previous studies of multiple sclerosis patients showed the existence of a positive association between multiple sclerosis and HLA--A3 and --B7, as well as a negative association with B12. These observations have been confirmed. In addition, a more marked association has been observed with two recently identified B-cell antigens, DRw2 and DRw3, closely related to the HLA--D locus. The presence of cold lymphocytotoxic antibodies was found to bear no relationship with those two specificities. These results suggest that two genes of the HLA--DR region may play a role in the pathogenesis of multiple sclerosis.

Epitopes↗
PubMed1978

[Visual evoked potentials in patients suspected of multiple sclerosis].

23 patients with symptoms suggestive of multiple sclerosis were examined with regard to the responses evoked by low frequency flash and also by flicker stimulation. The results obtained by flicker were compared with those reported on the responses evoked by different visual stimuli. The survey of the three parameters of analysis of the visual-evoked responses showed a very high proportion of pathological values.

Adolescent↗
PubMed1978

[So-called internuclear ophthalmoplegias. Electro-oculographic study].

A study is presented of three patients suffering from internuclear ophthalmoplegia without diplopia. The components of the nystagmus and the dysmetry of the oculomotor changes, as well as the difference in the respective speeds during abduction and adduction toward the side opposite to the lesion were recorded. A dysmetric component was found in the saccadic low amplitude movements (reading movements).

Adult↗
PubMed1978

[HLA-DRW antigens and multiple sclerosis].

Previous studies of multiple sclerosis patients showed the existence of a positive association between multiple sclerosis and HLA-A3 and B7, as well as a negative association with B12, These observations have been confirmed. In addition, a more marked association has been observed with two recently identified B-cell antigens, DRW2 and DRW3, closely related to HLA-D locus. The presence of cold lymphocytotoxic antibodies was found to bear no relationship with those two specificities. These results suggest that two genes of the HLA-DR region may play a role in the pathogenesis of multiple sclerosis.

Adolescent↗
PubMed1976

[Myoclonic encephalopathy due to bismuth salts. Negative search for an associated toxic element].

Five cases of bismuth associated encephalopathy have been observed in the area of Geneva (Switzerland). Thy typical clinical picture is described and the blood and urinary bismuth levels are analyzed in comparison with a group of patients on bismuth treatment but without encephalopathy. A link is established between these observations and previously reported cases of bismuth toxicity, and also with other toxic encephalopathies. With regard to pathogenesis, two hypotheses are discussed: alkylation of bismuth in vivo, and association with another neurotoxic element. With this in view, the urinary excretion of arsenic, lead and mercury was measured. The results were within normal limits.

Aged↗
PubMed1975

[Porto-systemic encephalo-myelopathy].

To avoid the dangerous consequences of gastro-intestinal haemorrhages in portal hypertension, portosystemic anastomosis is often performed. These operations unfortunately cause numerous complications among which isolated encephalopathy and encephalo-myelopathy hold pride of place. In spite of their different clinical, biological, therapeutic and anatomo-pathological behaviour, these two complications are undoubtedly the result of a common pathogenesis of which the details are not at present understood. It is, however, known that these involve complex metabolic disorders connected with the direct passage into the caval blood of products from the gut (ammonia, false neurotransmitters, ...). Experiments with rats have shown development of type II Alzheimer glia in the cerebellum after portocaval anastomosis; so far, spinal lesions have not been reproduced (10-76). In conclusion, it must be recognized that, as Lucien Leger (39) wrote, "by creating a new physiopathology, portal decompression raises as many questions as it solves."

Adult↗
PubMedDate not supplied

A modified light-cured denture identification technique.

Removable dental prostheses are lost frequently or stolen in nursing homes. Dental personnel may not be routinely available to many nursing home residents to place identification labels, and nursing staff members are not trained to use traditional denture marking techniques. This article describes a modified simple marking technique that may be used by either dental personnel or nursing staff members. Using ordinary sandpaper, lead pencil or ball pen, art and craft brush, direct light, and a mono-poly sealer of 1 part heat-cured clear methylmethacrylate powder mixed with 10 parts of autopolymerizing clear orthodontic methylmethacrylate liquid, 26 dentures were labeled for 19 nursing home residents. The technique was quick, cheap, easily applied, nonirritating to mouth tissues, and permanent.

Denture Identification Marking↗
PubMedDate not supplied

Tumor necrosis factor alpha production as a possible predictor of relapse in patients with multiple sclerosis.

No biological parameter is currently available as a specific marker of multiple sclerosis (MS) activity. The aim of this study was to determine whether an evolution of the neurological disability is associated with a modified profile of cytokine production. Clinical disease activity was quantitated by the Kurtzke's expanded disability status scale (EDSS). Whole blood was stimulated with phytohemagglutinin (PHA) for 2 hours at 37 degrees C and the activated plasma was assayed for Tumor necrosis factor alpha (TNF-alpha) and Interleukin-1 beta (IL-1 beta). Relapsing-remitting MS patients enduring a relapse (RRMS, in relapse) (721 +/- 58 pg/ml, n = 27) and chronic progressive MS (CPMS) patients (516 +/- 33 pg/ml, n = 17) had an higher TNF-alpha production capacity as compared to healthy subjects (143 +/- 25 pg/ml, n = 17), RRMS, stable patients, (123 +/- 11 pg/ml, n = 26) or other neurological diseases (OND) without immunological or inflammatory disease in the peripheral immune compartment (131 +/- 24 pg/ml, n = 14) (t test: p < 0.0001). IL-1 beta production was also significantly higher but to a lesser extent in the same conditions. Concentration of TNF-alpha was also found to be significantly higher in the cerebrospinal fluid (CSF) of CPMS patients (199 +/- 7.8 pg/ml, n = 7, p < 0.0001) but also in RRMS, in relapse (149 +/- 5.7 pg/ml, n = 11, p < 0.05) as compared to RRMS, stable (130 +/- 4.4 pg/ml, n = 7) or OND without inflammatory or immunological disease of the central nervous system (CNS) (142 +/- 6.2 pg/ml, n = 8).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

Thomas Morton's disease: a nerve entrapment syndrome. A new surgical technique.

A new interpretation of the surgical treatment of Morton's neuroma consists of release of the anterior edge of the deep plantar fascia (deep intermetacarpal ligament) without resection of the neuroma. In 206 patients treated with this technique, 83% had rapid and stable improvement. An additional 15% were improved but with some persistence of pain. Division of the ligament without excision of the neuroma provides good pain relief in most patients without the hazards of loss of sensation, loss of sweat production, or neuroma development in the nerve stump.

Adolescent↗