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G Gennser

Publications and source records attributed to G Gennser.

99 records · Page 6Linked to original sources

Pulse wave recording--development of a method for investigating foetal circulation in utero.

The need to investigate the elastic properties of arterial vessels 'in situ' for the early recognition of degenerative disorders in arteries has long been apparent. Volume pulses in defined segments of arteries can be evaluated for this purpose, and the present paper contains a survey of earlier attempts to quantify volume pulses by means of ultrasound. A presentation is given of a recently developed digital system, comprising a phase-locked echo tracker, capable of monitoring non-invasively the diameter and its pulsatile changes of a selected artery along two chosen image lines of a linear array ultrasound scanner. The physical limitations of tracking fast-moving ultrasound echoes by means of phase-locked range gating are reported and the advantage is emphasized of using a gate length of one full period. This system has been calibrated, tested and applied in measurements of pulse wave pattern and propagation velocity in the descending aorta of human foetuses in the last trimester of gestation. The present high-resolution echo-tracking method has yielded reproducible results in the foetus and appears suitable also for screening studies on adult vessels.

Blood Circulation↗

An ultrasonic system for diameter pulse tracking in arteries: problems and pitfalls.

Non-invasive ultrasonic techniques for measuring the mechanical behaviour of large arteries have a potential clinical application for physiological studies of the circulation and early detection of degenerative arterial disorders. A newly developed system for such purposes, comprising two double-echo trackers with zero-crossing phase-locked circuits and interfacing a B-mode real-time scanner, has been introduced for on-line recording of the diameter in a selected aortic segment. The aim of this report is to draw attention to the limitations of the technique in order to avoid misinterpretation of results. The various problems associated with the use of phase-locked echo followers for tracking sonic echoes of vessel pulse waves are summarized. The high spatial resolution of the measuring system is essential for estimating the elastic properties of the vessel, because the fractional changes of the diameter waveform during a heart cycle are small compared with the swings of intravascular pressure. Measuring errors may originate from either human or technical sources. From several viewpoints correct alignment of the ultrasonic beam vis-à-vis the vessel segment under consideration is crucial for obtaining valid measures. A thorough knowledge of the physics involved is essential for an adequate use of the instrument. With correct use, easily reproducible and reliable estimations are obtained of the mechanical properties of large vessel walls.

Aorta, Abdominal↗