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Biomedical subjects

G Gerstner

Publications and source records attributed to G Gerstner.

33 records · Page 2Linked to original sources
PubMed1980

[A new approach to the prophylaxis and therapy of puerperal mastitis (author's transl)].

The prolactin-inhibitor Bromocriptin was examined in an open study in comparison with Hexoestrol, a synthetic estrogen compound, in 31 patients with severe postpartal breast engorgement and in 38 patients with acute puerperal mastitis. In both indications a significantly faster clinical improvement was achieved with Bromocriptin. Also the incision-rate in cases of breast abscess was significantly lower in the Bromocriptin group. The inhibition of prolactin is considered the method of choice, as well in the prophylaxis as in the treatment of puerperal mastitis.

Bromocriptine↗
PubMed1980

[Herpes gestationis (author's transl)].

Herpes gestationis is a rare blistering disease of pregnancy and the puerperium which is difficult to differentiate from other bullous eruptions of pregnancy by clinical and histopathological criteria only. Caracteristic immunopathological features permit the exact classification of this disease. This is a report on three typical cases of herpes gestationis. The clinical, histopathological and immunopathological findings of the disease as well as treatment and maternal and fetal risks are discussed.

Female↗
PubMed1980

[Factors, which may influence breast feeding (author's transl)].

The case histories of 2197 mothers, who delivered at the 1st Department of Obstetrics and Gynecology of the University of Vienna in the years 1976 and 1977 were evaluated by the computer. 14 different parameters, which could have an influence on the incidence and duration of breast feeding were investigated. Our results suggest, that the incidence of breast feeding is declining with advancing years of the mother. An early reintegration into professional life after delivery has an effect on the duration of nursing. The family status and parity of the mother had no influence on the incidence and duration of breast feeding. Foreigners, as well as non-Roman Catholic mothers, who are represented mainly by guest workers from Yugoslavia and Turkey had a distinctly higher frequency of breast feeding of 74,6%, respectively 78,5% than average (67%). Also the duration of breast feeding of foreign mothers was above average. Women of higher socioeconomic classes had a higher incidence of breast feeding, as well as women, who had abortion or interruption or those using oral contraceptives. Operative delivery under narcosis and premature birth were accompanied by a significantly lower frequency of breast feeding. The rate of mastitis is at 1,4% in the group of breast feeding mothers.

Adult↗
PubMed1980

[Perioperative metronidazole-prophylaxis for cesarian section (author's transl].

A prospective, randomized clinical trial was conducted in 103 patients undergoing cesarian section to assess the efficacy of prophylactic, intravenously administered Metronidazole on the infectious morbidity. A group of 53 patients with perioperative Metronidazol-prophylaxis was compared to a similar controll-group without prophylaxis. Bacteriologic swabs were taken from the cervix pre- and postoperatively, using anaerobic transport media. Prophylactic Metronidazole reduced postoperative fever of more than 38 degrees C on two subsequent days from 60% in the controll-group to 30,2% in the Metronidazole-group (p less than 0,01) wound infections were reduced from 18% without to 5,7% with prophylaxis (p less than 0,05) and Endometritis from 30% without to 13,2% with prophylaxis (p less than 0,05). An additional antibiotic therapy was necessary in 44% of the cases in the controllgroup, compared to 24,5% of the cases in the Metronidazolegroup (p less than 0,05). The mean duration of hospitalisation was reduced from 12,1 +/- 3,2 days in the controll-group to 11,2 +/- 2,1 in the Metronidazole-group (p less than 0,01). Anaerobic bacteria were isolated from the servical swabs in 60% preoperatively, with a still increasing incidence to 72% postoperatively, compared to 7% in the Metronidazole-group. Our results suggest, that prophylactic, intravenously administered Metronidazol reduces the infectious morbidity following cesarian section due to the reduction of the anaerobic flora at the female genital-tract.

Adult↗
PubMed1980

Dopamine treatment for prevention of renal failure in patients with severe eclampsia.

Nine cases with severe convulsive eclampsia, undergoing intensive care, are reported. The main problem besides sedation and anti-hypertensive therapy was to bring about diuresis. Dopamin was administered in all cases, as in particularly severe cases the application of Furosemide and osmodiuretics does not succeed in the reestablishment of diuresis. The diluted drug was administered by means of a central venous catheter in a dosage of 3 microgram/kg body weight/min. Diuresis was achieved in all patients after few hours and the values of creatinin, rest-nitrogen and creatinin-clearance restored to normal. Also the consumption coagulopathy, due to the primarily restricted function of the kidneys, which was accompanied in the most cases by low platelet and high fibrinogen values, was controlled by the mentioned therapeutic procedure. The positive therapeutic effect of Dopamin is explained by the stimulation of the postulated specific renal dopamin receptors. The discussed antagonism between Dopamin and Angiotensin could be the cause of the vascular dilatation. Thus, Dopamin has a possibly causal significance in the treatment of oligoanuric eclamptic patients.

Acute Kidney Injury↗
PubMed1980

[Roentgenologic determination of maturity in low birthweight infants].

121 infants with low birthweight and a well known gestational age were divided into four groups: preterm infants, small for gestational age (SGA) infants, appropriate for gestational age (AGA) infants and infants with Clifford syndrome. With the 100 mm spot film technique X-rays of the right knee and ancle of the infants were taken and the size of the epiphyseal centers of the distal femur, the proximal tibia, the talus and the calcaneus was measured. The mean organ dose of the leg was only 2 mrad. All epiphyseal centers examined showed an increase from the 33rd to the 42nd week of gestation, which is in good agreement to previous studies. There was no evidence of a statistical difference of epiphyseal size between the four examined groups of neonates of low birthweight. Thus, in the present material with very close mean birthweights of the four groups, we were unable to distinguish preterm born infants from SGA infants with this method alone. This result suggests, that bone age is a more resistant criteria to fetal malnutrition than mass growth.

Age Determination by Skeleton↗
PubMed1979

[Antenatal assessment of fetal maturity--a comparison of ultrasound-cephalometry and radiology (author's transl)].

334 ultrasound-cephalometries and 231 X-ray fetographies were performed for antenatal assessment of fetal maturity as well as for exact estimation of gestational age in women with unknown date of donfinement. The accurance of the predictions was compared. Ultrasound-cephalometry gave best results when performed until the 20th week of gestation. A correct prediction was obtained in 80.4% of cases. After the 20th week of gestation, the accuracy of prediction decreased. Radiology on the contrary gave optimal results at the end of pregnancy. A correct prediction of the date of confinement was obtained in 73.8% of cases, when the X-ray fetography was performed between the 37th and 40th week of gestation. At the end of gestation radiography should be performed, if there is a discrepancy between ultrasound and clinical estimation or if ultrasound-cephalometry was not carried out in early pregnancy--especially if induction of labour is necessary.

Cephalometry↗
PubMed1979

[High dose gestagen therapy following primary radiation therapy of endometrial carcinoma (author's transl)].

By a high dose gestagen therapy following primary radiation therapy of endometrial carcinoma it was possible to reduce the recurrence-rate 12 months after therapy in comparison with a control-group without gestagen therapy by more than 50%. Therefore this method is recommended not only for treatment of far advanced carcinoma of the endometrium but also as prophylactic therapy in cases of early endometrium cancer.

Dilatation and Curettage↗
PubMed1979

Ultrastructure of the syncytiotrophoblast of the human term placenta in EPH-gestosis.

The ultrastructure of normal full-term placentae and of placentae of patients with EPH-gestosis was studied. To minimalize artificial changes puncture biopsies during cesarian section were performed. The main ultrastructural alterations in cases of EPH-gestosis can be summarized as follows: loss of the characteristic three-zonal pattern, increased deposits of fibrinoid, rarefication of microvilli, dilatation of the endoplasmic reticulum and of the Golgi apparatus.

Cell Membrane↗
PubMedDate not supplied

[Causes of lactation inhibition in the early puerperium (author's transl)].

In a retrospective study in 213 puerperal women, who had delivered at the 1st Department of Obstetrics and Gynecology of the University of Vienna before 1980, the individual cause for the primary or secondary inhibition of lactation with drugs in the early puerperium was evaluated. In 77.4% the lactation was carried out for maternal, in 22,6% for neonatal indications. Concerning the maternal causes in 23,9% the mother did not want to breast feed, in 17,8% "too little milk" and in 12,7% anamnestic breast-feeding problem at preceding deliveries were found. Maternal diseases were diagnosed in 9,4%, breast-feeding complications, like sore nipples, breast engorgement and mastitis in 5,2%, state after mammasurgery in 2.8%, an important drug therapy in 2,3%, sunken nipples in 1,9%, and several rare causes like adoption or arrest. Concerning the neonatal reasons prematurity was predominating in 16.9%, followed by antenatal fetal death and perinatal death in 3,3% and rarer diseases of the infant with reduced sucking power in 1,9% and one malformation (0.5%). Although several maternal and neonatal conditions still require the suppression of lactation, this could be avoided in a considerable percentage by adequate medical advise and encouragement for the patient. This should be a concern of all obstetricians today.

Breast Feeding↗