Six observations are presented of patients receiving intermitent rifampicin treatment (900 mg twice weekly) that developed acute renal failure during treatment (4 cases) or when treatment was taken up again, after an interruption of 6 months (2 cases). Following anuria of 4--14 days and nitrogen retention between 248 and 521 mg, the evolution was favourable. Clinical, biological and immunological data (anti-rifampicin antibodies were detected in 1/8 and 1/16 in 3 cases) suggest the immune origin of this type of renal accidents.

Acute Kidney Injury↗

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[Bacterial immunofluorescence in the intestinal juice in relation to other cellular and humoral immunity factors in the intestinal juice and blood serum of patients with chronic nonspecific enteropathy].

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Adult↗

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The nitroblue tetrazolium test in the estimation of urinary and serum leukocyte metabolism in urinary infections. A preliminary note.

For the study of leukocyte metabolism in the serum and the urine from 52 patients with urinary infections, the Nitroblue Tetrazolium (NBT) test was used for a qualitative estimation of leukocyturia. It was observed that 26 of the 52 patients (50%) presented higher values of NBT positive urinary neutrophils than in the control group. The NBT test might be useful in the estimation of the cellular immune response in the course of urinary infections.

Bacteriuria↗

PubMedDate not supplied

Evaluation by immunofluorescence of the urinary bacteria, of the therapy effectiveness in urinary infections.

The therapy effectiveness in urinary infections (UI) was investigated in 27 patients by the test of immunofluorescence of the urinary bacteria (IFUB) in relationship with bacteriuria, various other biologic investigations and tests of the immune response. The study revealed a complex involvement of the immune mechanisms in the UI occurrence and persistence, as well as a parallelism between the mechanisms of cellular and humoral immunity in some of the patients. The IFUB test could reveal the eventual germ persistence at the renal parenchyma level even in the absence of significant bacteriuria, thus suggesting the necessity of a long term suppressive therapy in such cases.

Anti-Bacterial Agents↗

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Bacterial immunofluorescence in the intestinal juice of patients with nonspecific chronic enteropathy.

The bacterial immunofluorescence (BIF) in the intestinal juice was studied by the method of Virginia Thomas in a group of 26 patients with nonspecific chronic enteropathy (NCE). Our investigation revealed BIF in jejunal juice in 16 of 26 patients with NCE. The BIF test may be useful for the estimation of immune response to pathogenic germs at the level of the intestine.

Bacteria↗