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Biomedical subjects

G Goder

Publications and source records attributed to G Goder.

At least 19 recordsLinked to original sources
PubMed2005

[Clinical value of amino acid imaging in paediatric brain tumours. Comparison with MRI].

PURPOSE: To evaluate single photon emission computed tomography (SPECT) using the amino acid l-3-[123I]-alpha-methyl tyrosine (IMT) and contrast enhanced magnetic resonance imaging (MRI) as diagnostic tools in primary paediatric brain tumours in respect of non-invasive tumour grading. Patients, materials, methods: 45 children with primary brain tumours were retrospectively evaluated. IMT uptake was quantified as tumour/nontumour-ratio, a 4-value-scale was used to measure gadolinium enhancement on contrast enhanced MRI. Statistical analyses were performed to evaluate IMT uptake and gadolinium enhancement in low (WHO I/II) and high (WHO III/IV) grade tumours and to disclose a potential relationship of IMT uptake to disruption of blood brain barrier as measured in corresponding MRI scans. RESULTS: IMT uptake above background level was observed in 35 of 45 patients. IMT uptake was slightly higher in high grade tumours but the difference failed to attain statistical significance. Grading of individual tumours was neither possible by IMT SPECT nor by gadolinium enhanced MRI. CONCLUSION: IMT is accumulated in most brain tumours in children. Tumour grading was not possible using IMT or contrast enhancement as determined by MRI. Neither morphological nor functional imaging can replace histology in paediatric brain tumours.

Adolescent↗
PubMed1990

[Clinical and pathologic characteristics of malignant lymphoma of the retina].

Two cases of malignant non-Hodgkin lymphoma of the retina and choroid with cerebral involvement are reported. In both cases, early infiltrates appear to have originated in the capillary layer of the choroid. Subsequently, Bruch's membrane was penetrated and tumorous infiltrates were found beneath the retinal pigment epithelium. The resulting reactions created a distinctive ophthalmoscopic picture, for which the term "leopardskin pattern" was coined. It may be helpful in early diagnosis, which with suitable therapy can prolong life.

Aged↗
PubMed1990

Lens safety study with Picumast dihydrochloride--a double masked study using the Scheimpflug method.

A double-masked study was performed to investigate a possible side effect of the antiallergic substance Picumast dihydrochloride on lens transparency. 372 patients with Picumast dihydrochloride- or Ketotifen-treatment regularly underwent ophthalmologic examinations and Scheimpflug photography of the anterior eye segment. Results of slitlamp examinations as well as microdensitometric analyzes of the film negatives after one year treatment did not reveal any evidence that Picumast dihydrochloride compromised lens transparency in humans.

Asthma↗
PubMed1983

[Value of computed tomography in tumor processes and tumor-like diseases in the maxillofacial region].

The usefulness of computed tomography is assessed based on findings from 24 patients with space occupying lesions of the bone structures of the face and sinuses. Fine needle biopsy performed under CT guidance facilitates cytological and histologic diagnosis. Computed tomography is especially valuable for staging tumor extent in the context of therapy planning but is also useful in detecting local recurrences. Complications of the procedure are also discussed.

Adolescent↗
PubMed1978

Pilocytic (juvenile) astrocytoma of the optic nerve. The influence of biopsy.

The biopsy and the decompression of a pilocytic (juvenile) astrocytoma of the optic nerve may caused increased mucoid formation and increased meningothelial reaction (meningioma formation) and therefore expansion of the tumour remnants. Experiences in the literature and our own clinical, histological and electrron microscopic observations are proof of this thesis. The correct diagnosis is easily established clinically. We should remain conservative if there is no necessity to intervene. A subtotal excision may be harmful.

Astrocytoma↗
PubMed1977

[Changes in the retinal vessels in mandibular nerve anesthesia. A potential for complications].

Examinations of the eyegrounds were made on thirty subjects after conduction anesthesia with xylocitin of the inferior alveolar nerve as well as on nine subjects after sodium chloride injections in order to determine the effect of mandibular conduction anesthesia on retinal vessels. Retinal vascular widths were measured and arteriovenous indices determined. The subjects were divided into groups according to preexisting general diseases, age, sex, and smoking habits. Retinal vascular changes were determined in dependence on age and smoking habits after injections made into the mandibular foramen, and the manner of origin and the results are discussed with particular reference to data reported in the literature.

Anesthesia, Conduction↗