Regarding "Variability and reliability of air plethysmographic measurements for the evaluation of chronic venous disease".
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Biomedical subjects
Publications and source records attributed to G Goren.
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PURPOSE: This study was designed to evaluate a recently introduced form of stripping of primary varicose veins by the technique of perforate-invaginate (PIN) stripping. METHODS: One hundred twelve consecutive limbs presenting with 91 long and 21 short saphenous varicosities displaying saphenofemoral or saphenopopliteal junctional escapes with varying length of greater or lesser saphenous (axial) reflux underwent operation in 1 year. All surgeries were performed in an office setting with the patient receiving locoregional anesthetic with use of the invaginated PIN stripping in conjunction with tributary hook-stab avulsion. RESULTS: In the 112 procedures performed, there were no tract hematomas or dysesthesias caused by nerve damage. Postoperative morbidity was nonexistent, permitting all patients to resume normal daily occupational and sporting activities immediately. CONCLUSIONS: PIN stripping is an excellent method of invagination stripping. There is a minimal likelihood of vein tearing. Compared with conventional ankle-to-groin (or popliteal fossa) stripping, PIN stripping is minimally invasive, does not cause damage to structures around the vein, does not require convalescence, eliminates the need for a lengthy distal second incision, can be performed in an office setting with the patient receiving locoregional anesthetic, and is most cost-efficient.
Pediatric patients with insulin-dependent diabetes mellitus were surveyed over a 5-month period to determine disposal practices of insulin syringes. Eighty-nine (79.5%) of 112 patients surveyed responded. Thirty-three percent of the responders disposed of syringes in accordance with recommendations of the local health department and the American Diabetes Association, while the remaining patients did not. Fifty-two percent of the patients rendered the syringes useless before disposal. The study revealed a need to educate and inform patients on the proper procedures that should be followed when disposing of syringes in the home.
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The management of primary varicose veins is evolving. Recovery time, cost, recurrence rate, and cosmesis are critical determinants. Classic "high ligation" and ankle-to-groin stripping is expensive, results in a long convalescence, and may produce unacceptable scarring and possible permanent nerve injury. This report describes the technique of stab evulsion phlebectomy performed in an outpatient setting. Under loco-regional anesthesia, and after high ligation, existing tributary and trunk varicosities are evulsed with specially designed hooks. The multiple stab incisions, 1.5- to 3-mm long, are closed with adhesive strips. Fifty-six patients, with 69 involved limbs, have been operated on during the past 9 months. Postoperative pain and complications were minimal. Convalescence was eliminated and all patients immediately resumed normal daily activities. Cosmesis was excellent. This technique is based on hemodynamically accurate principles. It effectively removes all varicosities, eliminates the proximal source of reflux, and disconnects potentially outflowing perforators, yet leaves in situ undamaged trunk veins, which may be used as potential vein grafts.
The recently accumulated hemodynamic and anatomic data on primary varicose disease, coupled with concomitant quest for maximal efficiency, cosmesis and saphenous vein preservation, is changing the surgical approach to the classical stripping operation. The long convalescence, with possible loss of income, the possible permanent nerve injury, and the possibility of removing normal truncular veins, makes the stripping operation, in many cases, an overkill. In contrast, the ambulatory stab evulsion phlebectomy (truncal and tributary), performed with the specially designed hooks and, performed in conjunction with ligation of the most proximal source of reflux (escape point), will effectively abolish the regurgitant flow and lower the existing increased ambulatory venous pressure. It will remove the tributary varicosities and thus disconnect all possible (distal) perforators, while undamaged veins, potential graft materials, are left in situ. The incisions of 1.5-3 mm, will guarantee excellent cosmesis, and due to minimal trauma, saphenous and sural nerve injury can be avoided as well. Performed in an ambulatory setting, under loco-regional anesthesia, which permits immediate resumption of the normal daly activities, makes the method appealing from the cost efficient point of view too. This hemodynamically and anatomically sound technique is however dependent on precise clinical as well as non invasive (Doppler ultrasound, air-plethysmography, and in certain cases duplex imaging) evaluation of each case, permitting the tailoring of an individualized treatment protocol for each patient.
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Mongrel dogs received transplanted kidneys following total nephrectomy. The whole blood was centrifuged to separate out the lymphocytic fraction, which was tagged with 51Cr. Renal accumulation of 51Cr was followed using imaging detectors. All allograft rejections were accompanied by a simultaneous rise in the count rate. Labeled lymphocytes can be used to detect canine renal rejection, and the authors feel that this technique can be applied to man.
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