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Biomedical subjects

G Greenstein

Publications and source records attributed to G Greenstein.

At least 19 recordsLinked to original sources

Periodontal response to mechanical non-surgical therapy: a review.

This literature review is concerned with the ability of personal oral hygiene and mechanical instrumentation to establish and maintain periodontal health. Clinical, microbiologic, and histologic responses to non-surgical therapy are evaluated to provide guidelines for expected treatment results. Factors that may limit the effectiveness of non-surgical therapy as a closed procedure are also addressed. These include length of therapy, skill of therapists, patient compliance, responsibility of clinician for maintenance, and disease activity status of the patient.

Dental Prophylaxis

The incidence of Encephalitozoon cuniculi in a commercial barrier-maintained rabbit breeding colony.

Between 1982 and 1987 sera from 4952 New Zealand White rabbits (Oryctolagus cuniculus) obtained from a single commercial supplier were tested for the presence of antibodies to Encephalitozoon cuniculi. A commercially available carbon immunoassay test kit was used. Initially 32.9% of the rabbits were seropositive with the number progressively decreasing to 2.3% by 1987. The reason for the significant decline in the incidence of infection was most likely due to a selection process for breeding stock instituted by the supplier based upon productivity, posture and weight of each animal.

Animals

Three-dimensional quantitative morphology of lumbar spinal ligaments.

The three-dimensional (3-D) morphology of lumbar spinal ligaments was studied using 22 functional spinal units. A specially constructed 3-D morphometer instrument was used for quantitative measurements of each ligament's attachment point locations, origins and insertions, and attachments to the lower and upper vertebral bodies, respectively. Lengths and orientations of the ligaments according to the vertebral level were then computed and presented in reference to a local anatomic coordinate system. Associated cross-sectional areas are also obtained.

Aged

Periodontal disease activity: a critical assessment.

Review of investigations using longitudinal probing and radiographic assessments indicate that the prevalence, magnitude, rate, and temporal patterns of periodontal destruction as well as the ability of clinical and laboratory tests to detect and predict loss of clinical attachment need further investigation. These unresolved issues are discussed and their impact on the practice of periodontics is examined.

Humans

Subgingival irrigation--an adjunct to periodontal therapy. Current status and future directions.

Science, in the search for truth, is dynamic and constantly changing. Periodically, an innovative idea such as subgingival irrigation emerges, which needs to be tested and retested. If the results are statistically and clinically meaningful, it then can be incorporated into treatment and maintenance regimes. This article addresses advantages and limitations of subgingival irrigation as it pertains to the treatment of patients with periodontitis. The subject is controversial, because while the role of supragingival irrigation is being recognized in the treatment of gingivitis, the status of subgingival irrigation in periodontitis therapy still needs further clarification. Four major themes are addressed within this text: (1) to explore the biologic rationale for subgingival irrigation, since treatment decisions must be based upon scientific data and not upon empiricisms; (2) to place in perspective the ability of subgingival irrigation (which also will be referred to as irrigation or lavage) to enhance periodontal health by assessing data from controlled studies; (3) to encourage use of subgingival irrigation as an adjunct to conventional therapy, in certain situations; and (4) to discourage bad execution of a good idea, because if limitations of lavage are not recognized, therapists may engage in ineffective treatment.

Chlorhexidine

Microbiologic assessments to enhance periodontal diagnosis.

Associations between microbes and progressive periodontal lesions provide the biologic rationale for using specific organisms as bacteriologic markers for disease activity. Rapid, specific and relatively inexpensive laboratory tests to identify bacteria have facilitated increased testing by clinicians. However, assays must be interpreted with regard to current concepts of etiology and pathogenesis of periodontal diseases. This paper addresses commonly used microbiologic assays and their shortcomings.

Bacteria

Chlorhexidine use.

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Chlorhexidine

Effects of subgingival irrigation on periodontal status.

Periodontal diseases are localized, plaque-related infections. Often, clinical signs of inflammation are not eradicated by supragingival plaque control, dictating that subgingival microbial populations must be reduced. Confirmation that it is possible to deliver medicaments to the base of deep pockets stimulated numerous investigations. This report evaluates the role of site-specific pharmacotherapy to enhance periodontal status.

Bacteria

Chlorhexidine. An adjunct to periodontal therapy.

Chlorhexidine is an effective antimicrobial agent. Its application can enhance periodontal therapy. The pharmacology of chlorhexidine and suggestions for its use are outlined. In addition, its potential for inducing cancer and bacterial resistance are discussed.

Absorption