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Biomedical subjects

G Gremion

Publications and source records attributed to G Gremion.

At least 19 recordsLinked to original sources

[Is stretching for sports performance still useful? A review of the literature].

Since 1980, according to several authors, it is accepted that increasing flexibility of a muscle-tendon unit allows a better performance and decreases sports injuries. Stretching is regularly included in warm-up and in cooling-down. However, there are contradictory findings in the literature. In contrast, since 1990, there's evidence suggesting that stretching not only does not prevent injuries, but can also decrease the level of performance. Some part of these contradictions can be explained by the various sports activities. Those requesting an increased flexibility, such as gymnastic, dancing or diving, necessitate pre-exercise stretching to optimize the level of performance. In contrary, for sports with slow stretch-shortening cycle such as jogging or cycling, there is no scientific data showing a positive effect of stretching.

Athletic Injuries↗

Two minimal incision fasciotomy for chronic exertional compartment syndrome of the lower leg.

Chronic exertional compartment syndrome (CECS) of the leg is a pathological condition often related to overuse in subject who engage repetitive physical activities. Fascial release is the mainstay of surgical management. The purpose of this study was to evaluate the results obtained with a double incision decompressive fasciotomy. Eighteen consecutive athletes with a diagnosis of anterior and/or lateral CECS of the leg were operated on with a minimal double incision fascial release after a mean period of 4 months after onset of symptoms. In 11 cases (61%) CECS was bilateral. Surgery was performed without tourniquet and active mobilization was starting immediately. Sports activities were resumed gradually at a mean period of 25 days. The athletes were followed until 2 years. All resumed pre-injury level sports activity. Two patients (18%) of the 11 who underwent to bilateral fasciotomy referred a sensation of leg weakness for an average period of 3 months. The surgical technique presented in this paper seems to be a good mean to treat anterior and lateral leg CECS. The use of tourniquet is deconselled to obtain an accurate intraoperative haemostasis so reducing the risk of post-operative haematoma.

Adult↗

Effect of a program of moderate physical activity on mental stress-induced increase in energy expenditure in obese women.

BACKGROUND: Energy restriction and physical activity are major components of weight reduction programs. Energy restriction is known to affect the sympathetic nervous system activity and to reduce several components of energy expenditure, including the stimulation of energy expenditure elicited by mental stress. The effect of physical activity on this parameter remains unknown. METHODS: This study was designed to assess the effect of physical training on the stimulation of energy expenditure during mental stress. Seven obese women (age 33 +/- 3 years, BMI 34.9 +/- 1.4 kg/m(2)) were studied before and after a 6 week program of aquagym (2 sessions of 50 min/week). Energy expenditure was measured by means of indirect calorimetry under hyperinsulinemic conditions before and during a 30 min mental stress. O(2) max was measured before and after physical training by means of the test of Balke. RESULTS: O(2) max was 23.4 ml/kg/min before physical training, and increased to 26.1 ml/kg/min at the completion of the training program (p<0.05). Body weight, resting energy expenditure and insulin-mediated glucose disposal [oxidative and non oxidative] were not modified after training. Mental stress increased energy expenditure by 12.3% before physical training (p<0.002 vs resting conditions) and by 12.6% after physical training (p<0.003 vs resting conditions, NS vs before physical training). CONCLUSION: Physical training per se does not alter the stimulation of energy expenditure induced by mental stress.

Adult↗

Oligo-amenorrheic long-distance runners may lose more bone in spine than in femur.

PURPOSE: Strenuous training can be associated with amenorrhea leading to amenorrhea-related accelerated bone loss. Insufficient calorie energy, calcium, and/or protein intakes can also be frequently encountered in women with intense training, possibly contributing to bone loss. Long-distance runners with or without regular menses (age range 19-37 yr) were prospectively studied. METHODS: Changes in areal bone mineral density (BMD) were measured at 1-yr interval. RESULTS: Among 10 eumenorrheic, 11 oligo-amenorrheic, and 9 oral contraceptive users, there was no difference in energy, calcium, or protein intakes. Baseline BMD values were significantly lower in the oligo-amenorrheic group than in the two others at the level of lumbar spine (anteroposterior view: 0.941+/-0.039 in oligo-amenorrheic vs 1.077+/-0.029 or 1.051 +/-0.017 g x cm(-2), P < 0.005, in the eumenorrheic and contraceptive user groups, respectively) but not in weight-bearing bone such as proximal and midshaft femur. Over a 1-yr interval, during which the three groups did not differ in terms of running distances and dietary intakes, oligo-amenorrheic women displayed a significant decrease in lumbar spine BMD in lateral view (-0.049+/-0.012 in oligo-amenorrheic vs -0.001+/-0.013 and 0.014+/-0.012 g x cm(-2), p < 0.005, in the eumenorrheic and contraceptive user groups, respectively). We did not detect any significant change in femoral neck, trochanter, or midshaft BMD. CONCLUSIONS: Oligo-amenorrhea in long-distance runners, with adequate dietary intakes, was associated with a decrease in BMD affecting more the lumbar spine than the proximal and midshaft femur during a 1-yr follow-up.

Adult↗

Physical activity and fat-free and fat mass by bioelectrical impedance in 3853 adults.

OBJECTIVE: To determine the effects of regular physical activity on body composition, as measured by bioelectrical impedance analysis (BIA), in a large Caucasian population of healthy subjects between 15 and 64 yr of age, and to observe the cross-sectional changes in body composition with increasing age. DESIGN: Cross-sectional comparison between sedentary and physically active adults (at least 3 h x wk(-1) at moderate or hard intensity level activity) during aging. SUBJECTS: A total of 3853 healthy adults (1036 sedentary and 1019 physically active men, and 1280 sedentary and 518 physically active women) between 15 and 64 yr of age. MEASUREMENTS: Height, weight, body mass index (BMI), and fat-free mass (FFM), fat mass, and % fat mass measured by 50-kHz BIA. RESULTS: Higher weight in older sedentary adults was due to a higher fat mass. In 55- to 64-yr-olds compared with 25- to 34-yr-olds, fat mass was 5.5 kg (P < 0.0001) higher in sedentary and 0.6 kg (P < 0.3) higher in physically active men, and 4.5 kg (P < 0.0001) and 2.0 kg (P < 0.04) higher in sedentary and physically active women, respectively. Physical activity was able to limit fat mass and weight gain in men over 25 yr of age and in women until 54 yr of age. Endurance type physical activity was not associated with increased FFM. For the same BMI, sedentary men and women have < 0.7 kg (P < 0.001) higher fat mass than physically active men and women. CONCLUSION: Therefore, the benefits of physical activity seem to include maintenance or prevention of an increase of BMI that in turn correlates with prevention of a fat mass increase for physically active subjects.

Adipose Tissue↗

Shoulder pain and dysfunction in hemiplegia: effects of functional electrical stimulation.

OBJECTIVE: To determine the influence of functional electrical stimulation (FES) on subluxation and shoulder pain in hemiplegic patients. DESIGN: Controlled study of 24 months' duration beginning in the first month after onset of stroke. SUBJECTS AND SETTING: One hundred twenty hemiplegic patients with both subluxed and painful shoulder were followed for rehabilitation before and after discharge between 1989 and 1993. All subjects received conventional rehabilitation based on the Bobath concept. In addition, patients were alternately assigned to a control group or to receive additional FES for 5 weeks on muscles surrounding their subluxed and painful shoulder. MAIN MEASURES: Clinical examinations, including range of motion, pain assessment, and x-rays, were performed at the start of the study, between the second and fourth weeks after onset of stroke, and subsequently at 6, 12, and 24 months. RESULTS: The FES group showed significantly more improvement than the control group in both pain relief (80.7% vs. 55.1%, p<.01) and reduction of subluxation (78.9% vs. 58.6%, p<.05). Furthermore, recovery of arm motion appeared to be significantly improved in the FES group (77.1% vs. 60.3% in the control group, p<.01). CONCLUSION: The FES program was significantly effective in reducing the severity of subluxation and pain and possibly may have facilitated recovery of the shoulder function in hemiplegic patients.

Adult↗

[Acute ruptures of the Achilles tendon--apropos of 14 conservatively treated cases].

GOAL OF THE STUDY: To analyse the results of non surgical treatment (cast for 12 weeks) for complete and recent rupture of Achilles tendon. MATERIAL AND METHODS: We reviewed with an average follow up of 2 years 14 patients (14 ruptures). All patients evaluated subjective results on a linear scale. Objective results were given by clinical examination, ultrasonography and performance testing. RESULTS: Subjective results were excellent for 50% of cases, good for 29% and fair for 21%. Amyotrophy of the calf was always noted (mean 15 cm). The maximum force was reduced by 22% and the endurance by 47% in comparison with the healthy calf. All sportsmen but one were able to continue their sport as before. None of them had to change their job. DISCUSSION: The conservative treatment of fresh ruptured Achilles tendon by plaster cast for 12 weeks gives satisfactory results in comparison with surgical treatment followed by 6 weeks immobilisation. The results are not so good when compared to conservative or surgical treatment followed by immediate mobilisation. CONCLUSION: Conservative treatment by plaster cast for 12 weeks should be applied to non compliant patients or to patients who are not concerned by the functional results or unable to follow a programme of reeducation or to patients with chronic skin lesions.

Achilles Tendon↗

Body composition by x-ray absorptiometry and bioelectrical impedance in female runners.

Body composition interests athletes since athletic performance is influenced by and dependent on the proportion and total amount of fat-free mass (FFM) and fat mass. The use of bioelectrical impedance (BIA) has increased recently since portable instruments make the measurements easy to execute and relatively inexpensive. The purpose of this study was to test the degree of relationship between FFM and fat mass calculated in elite female runners with 12 different BIA formulas reported in the literature and measured by dual-energy x-ray absorptiometry (DXA). The present study shows that body composition by BIA is valid in female runners. Prediction equations used to calculate FFM and fat mass must be appropriate for this population subgroup and validated against other methods, such as DXA and hydrodensitometry. Those formulas that performed well in the controls gave poor results in the female runner and vice versa. The below average fat mass noted in female runners suggests that prediction equations for untrained women with average fat mass are inappropriate. The formula by RJL Systems-2 for women: FFM = 5.091 + 0.6483.height2/resistance + 0.1996.weight gave best predictions of FFM in female runners. Further research is necessary to validate BIA prediction formulas in other athletes.

Absorptiometry, Photon↗

A trial with diclofenac HEP plaster as topical treatment in minor sport injuries.

Diclofenac HEP plaster was tested in an open study in the treatment of different traumatic sport and overload injuries, to confirm the results of efficacy and tolerability already shown in other clinical studies. A total of 101 patients were assigned to treatment and were eligible for the evaluation of results at the end of a 14-day treatment period. The average score of spontaneous pain, assessed by means of a verbal scale and a visual analogical scale, showed a clear difference in pain rating between the beginning and end of treatment. In general 60% pain reduction was observed. The difference in analgesic activity was already apparent on the 7th day of treatment (-28%). The reduction of pain was confirmed by changes in another subjective sign related to the injury: provoked pain. This symptom decreased in a manner comparable to spontaneous pain: 61% pain reduction after 2 weeks of treatment. Global assessment of efficacy, performed by the investigator at the end of treatment, showed the clear therapeutic activity of local treatment with diclofenac HEP plaster. Satisfactory results were obtained and only 18% of the patients (most of them with chronic and persistent pain) experienced ineffective pain relief at the end of the 2-week treatment. The beneficial effects of diclofenac HEP plaster on pain are confirmed by the patients' assessment, since almost identical scores were obtained. It is striking that the overall tolerance of diclofenac HEP plaster, applied topically twice a day for 2 weeks, was "good" or "excellent" in the 101 patients treated. Any side effect was reported on the patient's card and all the patients completed the study.

Administration, Cutaneous↗

[Eating behavior and bone mineral density in young women marathon participants].

Although reduced gonadal steroid hormone concentration appear to play a major role in lower trabecular bone density (BMD) in female marathon runners, dietary deficiencies and eating behaviors may also affect BMD. To investigate that possibility, dietary patterns and BMD were examined in 27 female regular marathon runners classified as eumenorrheic (8), amenorrheic (10) and under oral contraception (9). The results show a significant lower BMD in amenorrheic athletes but no dietary deficiencies. These results suggest that the eating behavior don't play any role in the lower BMD of our athletes.

Adolescent↗

[Physical performance and sedation: comparative study of the effects of a benzodiazepine (temazepam) and of a non-benzodiazepine hypnotic (zolpidem)].

It is well-known that many athletes experience some form of precompetition stress that may result in insomnia during the night before their competition. Yet, sleep withdrawal even if only partial, has a negative influence on performance, particularly when the type of exercise requires good psychomotor performance The purpose of the present study was to investigate whether the intake of a hypnotic drug would have negative effects on physical performance capacity. The authors have compared the effects of oral temazepam, a medium half-life benzodiazepine vs oral zolpidem, a short half-life non-benzodiazepine drug, vs placebo. A randomized double-blind trial was used to assess endurance, resistance, strength and coordination in 26 athletes. The results did not show any differences between the three groups, neither in physical performance characteristic nor in coordination. It is concluded that as regards the performance capacity, there is no risk for stressed athletes to use sleep inducers the night before their competition.

Adult↗