[The Working Group on the Prevention of S. pneumoniae Infections in Italy. The final report].
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Biomedical subjects
Publications and source records attributed to G Grilli.
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Modern oncology often obtains good results against earlier neoplasms, whilst it's still in difficulties against the advanced ones. The knowledge of paraneoplastic syndromes is crucial both to cure patients and to do an earlier diagnosis. When we recognize a paraneoplastic syndrome that comes before the clinic beginning of a neoplasm, perhaps we save a life. This review discusses all the main paraneoplastic syndromes, focusing mainly on their clinical aspect and reminding the most commonly associated cancers.
All measles cases occurred between 1989 and 1991 in the territory of the Local Health Unit 10--Marche Region--Italy, were studied in order to evaluate the characteristics of the disease and the transmission mechanisms. A total of 4 outbreaks were evidenced: 2 occurred in a 40,000 population municipality (with 46 and 87 cases, respectively), 1 in a 10,000 population municipality (with 35 cases) and 1 in two closely-related municipalities of 4,600 population (with 67 cases). The immune status of children between 1 and 10 years of age was evaluated adding the number of vaccinated children to the number of those who resulted having had the disease. Immune children were between 52.3% and 89.1%. During the outbreaks, the percentage of cases occurred in subjects over 10 years of age was, in total, 65.5. No cases needed hospitalization and only one case occurred in a vaccinated boy. In 189 cases the subject who presumably transmitted the disease was identified. Transmission occurred: within the school in 51.8% of the cases; within the family in 30.7%; during social activity in 10.0%; from inhabitants of the same house in 7.4%. The epidemiology of measles, in the area of this study, seems different from that described in the United States.
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