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Biomedical subjects

G Guarneri

Publications and source records attributed to G Guarneri.

18 recordsLinked to original sources

Effect of GnRH administration on blood polyamines and LH levels in normal and obese children.

Blood polyamines (spermidine and spermine) and LH levels have been studied after acute GnRH injection both in obese and normal weight children. In both groups LH values significantly increased after stimulation but reached higher peaks in normal children than in obese ones (P less than 0.05). On the contrary, polyamine levels increased significantly only in the normal weight children. LH peaked at 30 min and polyamines at 60 min after GnRH injection. On the basis of the proposed role of polyamines in hormone action and of our results, we suggest that polyamines may play a pivotal role in hormone responsiveness of hypothalamic-hypophyseal axis.

Adolescent

Osteoporosis and decline of gonadal function in the elderly male.

The bone mineral content was evaluated in 30 male subjects aged between 60 and 90 years using the relief of the percent cortical area (PCA) at the level of the second phalanx of the left-hand index finger, by Garn's method. This was to evaluate the rate of bone loss with increasing age. Testosterone, androstenedione, estrone, 17 beta-estradiol plasma levels were determined in all subjects by the RIA method. 60% of our patients showed increased bone resorption (PCA less than 55%); in these subjects testosterone and androstenedione plasma levels were significantly lower than in subjects not affected by osteoporosis. A positive linear correlation is evident between PCA and testosterone, androstenedione and estrone plasma levels. Thus, like in women, decline of gonadic function determines an increased bone resorption in men too.

Aged

[One case of acquired dyserythropoietic anemia: morphologic cytochemical study (author's transl)].

A case of acquired dyserythropoietic anemia is described in a sixty-six year old patient: is characterized by a very considerable pancitopenia, and by the presence in the bone-marrow of notable morphologic atipia both in erythroblastic line and in granulocitopoietic one. The iron kinetics and erythrocitic surviving are highly altered. The citochimic study points out the presence of myelocites with perossidasis-deficit and the presence of PAS positive erythroblasts. These data indicate metabolic anomalies that seem to localize the primitive deficit in the stem-cells.

Anemia, Hemolytic

Xanthogranulomatous salpingitis. Case report and review of the literature.

A xanthogranulomatous salpingitis, occurring in a fifty-two year old patient and appearing itself as a hydrosalpinx, is reported. The histological picture was characterized by the presence of several foamy histiocytes admixed with other inflammatory cells. Considerations about epidemiology, etiopathogenetic mechanisms and problems of differential diagnosis with other diseases are discussed.

Diagnosis, Differential