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Biomedical subjects

G Gullace

Publications and source records attributed to G Gullace.

29 records · Page 2Linked to original sources

[Systolic time intervals: echocardiographic study of the right and left ventricle. (author's transl)].

Right and left ventricular systolic time intervals are measured in 40 cardiopathic subjects and compared with the respective values concerning 20 normal subjects. The results show a modification: a) of the values concerning the right ventricle in presence of pathology interesting this ventricle; b) of the values concerning the left ventricle in presence of pathology interesting this ventricle; c) of the values concerning both the ventricles in presence of left ventricular pathology which has, also, interested the right ventricle. The AA. emphasize the importance of the right and left ventricular systolic time intervals not only to separate pathology interesting the right ventricle from that interesting the left ventricle, but also, to evaluate the ventricular performance and the stage of evolution and extension of the cardiopathy.

Adult↗

[Echo-phonomechanocardiographic relations of the systolic time intervals of the left ventricle (author's transl)].

15 normal subjects and 23 subjects with cardiac valve disease have been studied. All the subjects have undergone an echo-phonomechanocardiographic investigation with simultaneous recording of the tracings. The values of the systolic time intervals have been obtained from the echo-cardiographic tracings and compared with those obtained from the phonomechanocardiographic tracings evaluating the differences between them. The comparison has pointed out values nearly coincident, providing useful elements about the relations existing between the cardiac sounds and the moments of closure of the mitral and aortic valves. Moreover, the two techniques are considered useful and valid in the evaluation of the left ventricle performance by the systolic time intervals, especially when the recording is carried out simultaneously.

Adult↗

[Mitral valve prolapse in a family group. Clinico-instrumental findings].

Clinical and echo-phonomechanocardiographic reports. The results concerning 7 subjects with mitral valve prolapse (M.V.P.), all members of the same familiar group, are reported. The anamnestic investigation for cardio-vascular deseases, Marfan's syndrome or other abnormalities referred to mesenchimopathies has been negative. No subject with M.V.P. has referred subjective cardio-vascular symptoms nor radiological, ecgraphic and echo-phonomechanocardiographic signs of reduced cardiac function, have been pointed out. The phonomechanocardiographic tracings have shown a variable and low-amplitude click. The echocardiographic tracings have shown a U-shaped (3 cases) and double U-shaped (1 case) pansystolic, early systolic (2 cases) and of doubtful classification (1 case) prolapse. The hypothesis of an autosomal dominant form of inheritance of the desease with not yet clear mechanism of genetic transmission is confirmed. Furthermore, environmental and genetic factors that interfere with the orderly valvular formation at a certain stage of the fetal development, are referred. The Authors remark the necessity of further investigations, among more familiar groups, for identifying the genetic-environmental factors, that, eventually, could have any implication in the ethiopathogenetic mechanism of the disease. The report of "silent" forms and the not yet completely known evolution of the M.V.P. don't justify its not-recognition.

Adult↗

[Clinical and echo-phonomechanocardiographic study of the mitral valve prolapse (author's transl)].

The results of a study of 32 patients with the clinical and auscultatory suspect of M.V.P., confirmed echo-cardiographically, are reported. Part of the pathogenetic cause of the symptomatology and ECgraphic alterations are attributed to the hypomagnesiemia. The relation between exercise test positivity and gravity of the symptomatology is confirmed. The phonomechanocardiographic tracings were studied and the morphological features from C.P. and apexcardiogram are described and shown, with particular attention given to the clicks and systolic murmurs. The authors describe three types of prolapse, early, "U"-and "double U"--shaped pansystolic, and, relating echo-to-phonomechanocardiographic results, point out features which seem typical of the M.V.P. Echo-phono mechanocardiography is confirmed as a technique which is useful and sufficiently safe and reliable in diagnosing, detecting and following the disease in its not yet perfectly acknowledged evolution. It avoids the use of invasive tools which could become extremely dangerous.

Adult↗

[Left atrial rhythm. Electrocardiographic study (author's transl)].

The electrocardiograms of 15 left atrial rhythm and sinusal rhythm patients are studied. The spontaneous occurrence of LAR and the possibility of return to SR by vagal stimulation manoeuvers are reported. The electrocardiographic modifications of the ectopic rhythm are shown and compared either with those of the coronary sinus rhythm or junctional A-V rhythm, or with those of the tracings recorded during atrial pacing. The intermittent occurrence of the LAR in the studied cases is theoretically ascribed to the awakening of an ectopic focus, localized in the left atrium, acting as a new pace-maker because of its excited activity or abnormal depression of the sinus.

Adolescent↗

[Effects of amyl nitrite on left ventricular systole times in normal subjects and those with aortic valvulopathy. Echophonomechanographic assessment].

Echophonomechanographic traces showing systole times, the circumferential restriction time, and the ejection fraction were compared in normal subjects, those with aortic stenosis, and those with aortic insufficiency under basal conditions and after 45" inhalation of amyl nitrite. Significant changes in these parameters after stimulation were noted in the normal subjects only, while the differences between the two groups of patients and the controls were also statistically significant under both experimental conditions. The fact that the diseased subjects did not reach the values noted in the controls is attributed to a latent contractility defect under basal conditions that is rendered evident by amyl nitrite. Stress is laid on the usefulness of the drug in the detection of left ventricle myocardial contraction defects via the analysis of ventricular function.

Adult↗