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Biomedical subjects

G Gutensohn

Publications and source records attributed to G Gutensohn.

11 recordsLinked to original sources

[The single daily dose of gentamicin in the treatment of urinary tract infections (author's transl)].

Gentamicin was administered intravenously or intramuscularly to 165 patients with non-obstructive urinary tract infections. 3 prospectively randomised groups were formed in which gentamicin was given either once daily (120 mg), twice daily (40/80 mg) or three times daily (40 mg). Clinically and bacteriologically an equally good improvement of the condition appeared in all groups. The mode of application selected had no influence on the therapeutic success in 86--95%. Since with the single daily injection of 120 mg gentamicin the proportion of side effects did not increase, this therapeutic plan can be recommended for outpatient treatment in urological and internal medical practice.

Adult↗

[Treatment of alkyl phosphate poisoning with purified serum cholinesterase (author's transl)].

A 26-years-old man injected himself intramuscularly with 3.75 gram of demeton methyl in an attempt to commit suicide. After 36 hours severe symptoms of poisoning developed with loss of consciousness and respiratory arrest. As symptomatic treatment failed to improve his condition has given injections of purified serum cholinesterase. This was followed by a rise in the cholin esterase levels and the increased activity was accompanied by a rapid and definite improvement in the clinical findings. The results clearly indicate the usefulness of this method of treatment. Transfusions of fresh blood to counteract the cholin esterase deficiency are inadvisable because of the risks of complications. Substitution therapy with serum cholinesterase must be accompanied by administration of large doses of atropine.

Adult↗