Hypomastia and mitral-valve prolapse. Evidence of a linked embryologic and mesenchymal dysplasia.
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Biomedical subjects
Publications and source records attributed to G H Derman.
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Polytetrafluoroethylene (PTFE) grafts can successfully be used as a microvascular prosthetic grafting material in rats with patency results of 90%. There was not a significant difference between patency percentages obtained with the PTFE grafts in comparison with autologous vein grafts. Excellent patency was achieved at 40 days for all of the interposition grafts in this study. Aspirin and dipyridamole did not improve patency.
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It is imperative that the reconstructive surgeon master microsurgical technique prior to engaging in clinical microsurgery. The primary task of developing this expertise is most efficiently performed in the microsurgical laboratory. The immediate availability of the materials necessary to establish a laboratory, their low cost, and the numerous microsurgical exercises that can be performed in such a facility make the microsurgical laboratory a practical and necessary addition to surgical training centers. Postoperative examination of repaired vessels, including light and electron microscopic studies, is important in pointing out errors and weaknesses so that they can be, respectively, corrected and strengthened. The surgeon wishing to learn microsurgery must earnestly devote much time and energy to the pursuit of perfection. With the aid of a microsurgical laboratory, practice, and strict adherence to the established guidelines of microsurgical technique, the reconstructive surgeon can develop the skills necessary to master the art of microsurgery.
An intraluminal stent fashioned from medical grade Silastic was used for technical assistance in performing 23 microvascular anastomoses. Twenty control and 20 stent arterial anastomoses were completed. Patency rates of 100 per cent in both the stent and control anastomoses were found by radical pressure testing immediately postoperatively and after an interval of two weeks. Electron microscopic and light microscopic studies showed no increase in damage to the vessel wall or increase in connective tissue reaction. Under the conditions of this experiment the Silastic stent can be used safely for assistance in performing microarterial anastomoses. Preliminary studies in six microvenous anastomoses have also shown no significant difference postoperatively between the stent and control anastomoses, both having a 100 per cent patency rate.