PubMed Health⌕ Search

Biomedical subjects

G H Frey

Publications and source records attributed to G H Frey.

4 recordsLinked to original sources

Serum ferritin and myocardial infarct.

In a recent Finnish study, an association of high serum ferritin levels with excess risk of myocardial infarction in men was reported. This was the first such report in the literature so we decided to review the clinical records of 298 male patient seen over a 10-year period in Southern West Virginia, in whom serum ferritin levels were obtained. Of the 32 patients who experienced an acute myocardial infarction, there were no significant statistical differences between their mean ferritin levels and the ferritin levels of the 266 patients with no myocardial infarct. Only two of the 32 patients with myocardial infarct showed an elevated serum ferritin level, so our findings do not support the hypothesis that high serum ferritin levels are associated with myocardial infarct.

Adult↗

Use of aspartame by apparently healthy children and adolescents.

This study was conducted to determine the effects and the differences, if any, resulting from the ingestion of aspartame (sweetener) versus sucrose. A 13-wk, double-blind study was conducted using 126 apparently healthy children and adolescents as panelists. Individuals were randomly assigned in a double-blind design to aspartame or sucrose in each of five age groups; dosage levels were assigned according to age and weight groups. Physical examinations and special eye examinations were performed at the beginning and end of the study. Other parameters determined including laboratory tests of liver and renal function, hematologic status, and plasma levels of phenylalanine and tyrosine. Clinically significant differences in laboratory parameters measured could not be demonstrated; all mean values were within normal limits. No unusual findings were observed in phenylalanine or tyrosine levels. All phenylpyruvic acid and methanol determinations were negative. No important physical changes occurred, and no product-related side effects were reported.

Acne Vulgaris↗