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Biomedical subjects

G H Green

Publications and source records attributed to G H Green.

At least 19 recordsLinked to original sources
PubMed1986

William Liley and fetal transfusion: a perspective in fetal medicine.

The circumstances under which Sir William Liley, KCMG, first conceived the idea of blood transfusion to mitigate temporarily the effects of severe haemolytic disease in an affected fetus, and carried it to a successful conclusion, all in a former war-time American army hospital, are presented. The significance of his achievement is estimated as being, not so much a major advance in the management of a serious fetal disease (which if left to itself would eventually disappear, albeit in millennia), but a first real demonstration that the fetus is accessible to skilled diagnosis and treatment, and thus has the inalienable right to be as much regarded as a patient as anybody else.

Blood Transfusion, Intrauterine↗
PubMed1985

A Tudor cesarean section.

The history of the only and fatal pregnancy of Queen Jane Seymour, the third wife of King Henry VIII, has been reinvestigated and is presented herein. Her death on 24 october 1537, 12 days after the delivery of Edward VI, is believed to have been due to peritonitis after a cesarean section which was performed for political reasons. Since the written evidence for this lacks complete proof, it is indicated that the physical witness of an abdominal operation may still exist.

Cesarean Section↗
PubMed1979

Rising cervical cancer mortality in young New Zealand women.

New Zealand age-standardised mortality rates for cervical cancer in women 20-34, 35-64 and 65 years and older show that mortality has been falling steadily for women 35 years and older ever since 1941, 14 years before cytology screening was introduced. Mortality has risen significantly since about 1959 in women 20-34 years old. These findings cast doubt on the value of screening. Possible causes of the increased mortality in young women include a cohort effect, increased promiscuity, and the effect of steroidal compounds on cervical epithelium.

Adult↗
PubMed1978

Cervical cancer and cytology screening in New Zealand.

Cytology screening, used in New Zealand since 1955 at an intensity comparable to that in Canada generally, has not favourably affected incidence and mortality rates for cervical cancer; these have actually risen significantly in 20 to 34-year-old New Zealand women. Canadian claims that mortality falls are related to intensity of cytological screening are not justifiable, so that the significance of the 'pre-cancers' revealed by cytology and the value of population screening would seem to be doubtful.

Adult↗
PubMed1976

Radiation-induced immune changes in patients with cancer of the cervix.

Immunological methods were used to estimate the therapeutic effect of irradiation and its influence on the immune capacity of patients with cervical cancer. Patients were examined during and following radiotherapy by means of lymphocyte counts, lymphocytic response to phytohaemagglutinin (PHA), and the depressive effect of their sera on the response of normal lymphocytes PHA stimulation. Lymphocyte counts and lymphocyte responses during radiotherapy were depressed to 20 to 50 per cent and 10 to 33 per cent respectively of the values found before treatment. Lymphopenia and depressed T-cell function persisted for years in many patients. The highest values for both lymphocyte counts and reactivities were found in those patients who had unexpectedly good responses to radiotherapy. The immunodepressive effect of patients' sera on normal lymphocyte reactivity decreased and disappeared during therapy and was not present in previously treated patients showing a good prognosis, whereas it showed no change or even increased during therapy in patients with a poor prognosis. The results suggest that not only does immune capacity influence the effect of radiation and the prognosis of the patient, but also that study of the serum-depressive effect could give important information about both the dosage and therapeutic effects of irradiation.

Adult↗
PubMed1975

Localized deposition of calcium oxalate around a pulmonary Aspergillus niger fungus ball.

A case of pulmonary Aspergillus niger fungus ball is presented. Crystals of calcium oxalate, presumably derived from oxalic acid produced by the fungus, were deposited in tissues around the fungus ball. The crystals were identified by x-ray diffraction analysis. Histochemical technics for the identification of calcium oxalate were applied, and evaluation of those showed Yasue's silver nitrate-rubeanic acid method to be the most satisfactory. More frequently used methods for identifying calcium salts in tissues may give equivocal reactions. Oxalic acid may cause localized tissue damage, and if this affects blood vessels severe hemorrhage may follow.

Aspergillosis↗