Biomedical subjects
Publications and source records attributed to G H Muller.
This article deals with the unique skin disorders seen only in the Shar-Pei. The difference between skin diseases in Shar-Pei and other breeds is described. Prevention and treatment are discussed. Suggestions are given to alter the breed's anatomy slightly to decrease the genetic predisposition to certain dermatoses.
A breast usually has a conical or pyramidal shape. The best way to reduce such a structure is to resect the base. This reduction can be mathematically defined following the principles of the architecture of pyramids. Once the volume is decreased, a conical shape and a stable position has to be recreated. Using the principle of cathedral architecture, a key-stone, is created to stabilise the mammary arch. The architectural study is presented as well as its adaptation to the breast.
Mycosis fungoides was initially diagnosed in a 7.5-year-old German Shepherd Dog with generalized canine cutaneous histiocytoma. Lesions resolved without treatment over approximately 16 weeks. The final diagnosis of histiocytoma with 2 histopathologic patterns was obtained by use of a special staining technique for the detection of lysozyme found in histiocytes.
A case of secondary breast reconstruction is presented with treatment at the same time of lymphoedema of the upper arm. In cases of intolerance of silastic implant or following irradiation after mastectomy, a TRAM flap is performed as a first step, and at the time of nipple areolar grafting, the arm is treated with a muscular anterior latissimus dorsi flap and suction of the fore-arm.
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Ichthyosis in 2 dogs was characterized by extreme hyperkeratosis on all or part of the skin and by extreme thickening of the digital and metapodial pads. The skin disorder closely resembled human lamellar ichthyosis, in which the histologic features include a thickened granular layer, mitotic figures, and dense collections of coarse keratohyaline granules. The disease was believed to be inherited, probably autosomal recessive, inasmuch as none of the parents was affected. Treatment of 1 dog with 5% lactic acid in hydrophilic ointment reduced the hyperkeratosis and decreased the shedding of scales.
A slowly evolving subcutaneous mycosis in a 10-year-old domestic shorthair cat was found to be caused by Drechslera spicifera, the imperfect state of ascomycete Cochliobolus spicifer. The cat had circular, nodular, granulomatous lesions over its sternum. Scattered individual and small groups of septate hyphae and chlamydospores were found in histologic sections. Many of the hyphae also had bizarre dilatations. Most of the fungal elements were hyaline; a few, however, were dematiacious. Because the fungus was not organized into granules in tissue, the disease could not be classified as a mycetoma. The preferred name for infections of this type is phaeohyphomycosis.
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