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G H Petrescu

Publications and source records attributed to G H Petrescu.

3 recordsLinked to original sources
PubMed1975

[Cerebral renin-like activity in different functional conditions (author's transl)].

Using the Boucher micromethod of determining renin activity in the frontoparietal cortex, brain stem, hypothalamus, hypophysis, and epiphysis rat tissue in different functional conditions, we have observed the following: 1 In rats previously treated with an I. V., injection of 1-1.5 ml 10% NaCl, an increase of renin-like activity was found in the cerebral cortex, brain stem and hypothalamus, whereas in the grandular tissue there was a significant decrease...

Angiotensin II↗
PubMedDate not supplied

Some neural effects of adenosin.

The possible neural effects of adenosine were investigated by using electrophysiological techniques at the level of some central and peripheral synapses. The evoked potentials in the somatosensorial cerebral cortex are influenced according to both the type of administration and the level of the electrical stimulation. While the local application does not induce significant alterations, the intrathalamic injections and the perfusion of the IIIrd cerebral ventricle do change the distribution of activated units at the level of different cortical layers especially during the peripheral stimulation. The frequency of spontaneous miniature discharges intracellularly recorded in the neuromuscular junction (mepp) is significantly depressed by adenosine. This effect is calcium- and dose-dependent. The end plate potentials (EPP) were also depressed. The statistical binomial analysis of the phenomenon indicated that adenosine induces a decrease if the presynaptic pool of the available transmitter. The data obtained demonstrate a presynaptic inhibitory action of adenosine beside its known vascular and metaholic effects.

Adenosine↗