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Biomedical subjects

G H Poole

Publications and source records attributed to G H Poole.

7 recordsLinked to original sources

Acute laparoscopic cholecystectomy. A case controlled study.

BACKGROUND: Acute laparoscopic cholecystectomy (ALC) has been performed successfully at a number of institutions. Interval laparoscopic cholecystectomy (ILC) is preferred by many surgeons because of its convenience and a perceived increased risk with acute surgery. METHODS: A case control study was undertaken. The case group was a consecutive series of patients who underwent ALC between October 1996 and October 1997. The control group underwent ILC between March 1996 and March 1997 after at least one previous acute admission for gallstone disease. RESULTS: There were 81 patients in the case group and 100 in the control group. The groups were similar in terms of age, sex, and clinical diagnosis. Operative times (70 min vs 78 min, p = 0.60), major complications (4.9% vs 2%, p = 0.41), minor complications (4.9% vs 7%, p = 0.76), and conversion rates (7. 4% vs 7%) were similar in both groups. There were no bile duct injuries in either group. The median total hospital stay was 5 days in the case group and 8 days in the control group (p < 0.0001). CONCLUSIONS: Acute laparoscopic cholecystectomy can be performed safely at the first hospital admission, thus reducing hospital stay and minimizing inconvenience to patients.

Adult↗

Laparoscopic Tenckhoff catheter insertion: a prospective study of a new technique.

BACKGROUND: This study describes a new technique of laparoscopic Tenckhoff catheter insertion. METHODS: During a 12-month period, 53 consecutive patients requiring insertion of peritoneal dialysis catheters were studied prospectively. A new technique of laparoscopic insertion was developed. RESULTS: Forty-eight patients out of 49 (98%) had successful insertion. Four patients were excluded with active peritonitis. There was an early complication rate of 8% (4/49) and a late complication rate of 14% (7/49). There was 12% overall failure of catheter with a mean follow up of 6 (1-13) months. CONCLUSION: This new laparoscopic technique maximizes the advantages of laparoscopic surgery and has complication rates which compare favourably with other open and laparoscopic techniques.

Adolescent↗

Comparison of a Modified Atmosphere Stunning-Killing System to conventional electrical stunning and killing on selected broiler breast muscle rigor development and meat quality attributes.

Two experiments were conducted to compare the effects of a 70:30 argon:carbon dioxide Modified Atmosphere Stun-Kill (MASK) system to both a low voltage (LV) and a high current (HC) electrical stunning and conventional killing system on broiler breast rigor development and meat quality. In Experiment 1, the effects on breast muscle pH and meat tenderness of the MASK system and the LV system were compared. In Experiment 2, the MASK system was compared to both HC and LV stunning for pH, R-value, C.I.E. L*, a*, b*, cooked yield, and tenderness of broiler breast meat. In Experiment 1, there were no significant differences in breast muscle pH between LV and MASK, except at 24 h. Only at 5 h post-mortem did the MASK system result in significantly tougher breast meat. In Experiment 2, there were no significant differences between treatments in breast muscle color or cooked yield at any sampling time. The breast muscle from birds subjected to the HC stun had consistently higher pH values until 5 h post-mortem, at which time the breast meat from birds subjected to the MASK system had higher pH. R-value data showed a similar trend, with the HC stunned birds having the lower R-values until 5 h post-mortem. Breast meat tenderness values for the three treatments were significantly different only at 3 and 5 h post-mortem, when birds stunned with HC had the highest shear values. The MASK system did not exhibit any rigor accelerating benefits when compared to LV stunning and conventional killing, and only minimal rigor acceleration when compared to HC killing.

Abattoirs↗

Modifications to the Hasson technique.

Blind peritoneal penetration with a Veress needle is an unnecessary risk. This risk is reduced by the use of the 'Hasson technique'. We suggest two modifications to the Hasson technique which make it easier to undertake, and reduce the problem of peri-port air leak.

Humans↗

Diagnosis of breast cancer with core-biopsy and fine needle aspiration cytology.

BACKGROUND: Patients who are elderly or who have locally advanced breast cancer may initially receive primary medical therapy. METHODS: In order to avoid open biopsy in such patients, we routinely perform both fine needle aspiration cytology (FNAC) and core-biopsy at the first clinic visit. RESULTS: A retrospective review showed that of 109 such patients, 87 (80%) had the diagnosis confirmed on FNAC and 96 (88%) on core-biopsy. Only eight patients did not have a diagnostic result from the first clinic visit, and five of these patients were diagnosed on a repeat core-biopsy or FNAC. The remaining three patients had suspicious FNAC. Overall 97% had one or both investigations positive. CONCLUSIONS: When considered alone core-biopsy was superior to FNAC. In this series the combined diagnostic approach of FNAC and core-biopsy has allowed outpatient diagnosis for virtually all patients.

Aged↗

A comparison of argon, carbon dioxide, and nitrogen in a broiler killing system.

Argon, CO2, and N2 gasses were each evaluated in a broiler chicken gas killing system. Birds were killed by individual exposure to one of the three gasses for 2 min in a flow-through system. The gasses were evaluated by determining the time, in seconds, for the following responses: first reaction to the gas, loss of posture, eye closure, initiation of death struggle, and cessation of respiration. Percentage blood loss over a 3-min bleed time was determined by weight loss. Breast muscle pH values were determined at 15 min and 24 h post-mortem on the Pectoralis major muscle. Carbon dioxide resulted in the earliest first reaction, loss of posture, eye closure, and initiation of struggle. Argon and N2 exhibited a delayed first reaction, a less severe early reaction, but a more severe unconscious death struggle. All birds died in approximately 75 s. Results indicate that the flow-through gas system takes longer to kill broilers than the immersion systems previously reported. Gas killing resulted in lower (P < .05) blood loss. Initial breast muscle pH values were significantly highest for the birds killed with CO2, followed by the control treatment, which was significantly higher than the values for broilers killed with either Ar or N2. After 24 h of chilling, there were no differences in broiler breast muscle pH among the four treatments. These results indicated that a flow-through gassing chamber may be a feasible, although slower, method of performing gas killing as compared to an immersion system.

Abattoirs↗

One hundred consecutive cases of flap lacerations of the leg in ageing patients.

AIM: To define the cost of inpatient treatment of flap laceration to the leg in ageing patients. METHODS: One hundred consecutive admissions over a 19 month period were reviewed retrospectively. RESULTS: The mean age of flap laceration of the leg patients was 77.5 years (50-93). The mean bed stay was 14.53 days (1-36). Most patients (84%) were treated with debridement and split skin grafting. The total cost of treatment was $551,390.00. The mean delay before surgery was 41.2 hours. 92% of patients returned to the same preoperative social circumstances. CONCLUSIONS: Flap laceration of the leg is expensive to treat in hospital. There are a number of strategies in which bed stay and costs can be reduced. These include early and aggressive surgery, the use of meshed skin graft, early mobilisation and early involvement of social support services.

Age Factors↗