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Biomedical subjects

G H Purdie

Publications and source records attributed to G H Purdie.

6 recordsLinked to original sources
PubMed1991

Interoperator variability in quantitative electroencephalography.

The purpose of the study was to determine whether quantitative or discriminant analysis of the electroencephalograph (EEG) would vary significantly when the same EEG was analysed by 3 different operators. EEGs on 10 healthy volunteers were recorded on the Cadwell Spectrum AT 386, using the Electrocap (10-20 system). The EEGs were analysed independently, with each operator selecting the first 48 artifact-free epochs. The results were analysed using the non-parametric Friedman two-way analysis of variance (ANOVA) for the discrimination analysis and a one-way ANOVA for the monopolar and bipolar Absolute Power raw measures. Statistical analysis of the discriminant data showed no significant differences between operators, with 7 of 10 studies yielding the same results. The remaining 3 studies were classified either as borderline or normal when analysed by different operators. Although a series of "t" tests comparing 2 operators showed most variability occurring in Absolute Power as compared with Relative Power, Power Asymmetry and Coherence, ANOVA of the raw mono- and bipolar Absolute Power measures showed no significant differences between the operators at the P = 0.05 level. Thus the differences between the operators were non-significant when comparing quantitative EEG analyses with respect to both the raw measures and the discriminant analyses.

Analysis of Variance↗
PubMed1991

Familial spastic paraplegia: an electrophysiological study of central sensory conduction pathways.

An electrophysiological assessment has been performed studying somatosensory, visual and auditory pathways in clinically affected and unaffected members from 4 pedigrees with the autosomal form of 'pure' familial spastic paraplegia (n = 32). In some members from 2 families, testing of all 3 sensory pathways showed abnormal results, even in those clinically unaffected. In another family, some had abnormal somatosensory and visual pathways, with no involvement of the auditory pathway. In a further family, the somatosensory and brainstem auditory pathways were abnormal, with sparing of the visual pathway. These findings indicate that the neuronal degeneration in familial spastic paraplegia extends beyond the spinal cord and involves the visual and auditory pathways. The differences between families, and the asymptomatic abnormalities in clinically unaffected members, suggest diversity in the expression of the genetic defect.

Evoked Potentials, Auditory, Brain Stem↗
PubMed1983

The hypereosinophilic syndrome.

The hypereosinophilic syndrome groups together patients with idiopathic eosinophilia and diffuse organ infiltration with eosinophils. It appears to be a continuum of disease from the asymptomatic patient with skin and heart disease at one end to eosinophilic leukaemia at the other. A case is described of a young woman who presented with asthma, mononeuropathy multiplex and eosinophilia and subsequently developed eosinophilic gastroenteritis, vasculitis and probable myocarditis. The response to prednisolone has been pleasing.

Adult↗
PubMed1978

Posterior fossa arachnoid cysts: two case reports.

2 cases of posterior fossa arachnoid cyst are discussed. In the first, it is likely that perinatal factors were responsible for the temporal lobe pathology and the formation of the cyst. Progressive dilatation of the temporal horn may have then been caused by obstruction from the cyst. In the second case, minor head trauma was a possible mechanism for the cyst production, although it seemed irrelevant to the mode of clinical presentation.

Adolescent↗