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Biomedical subjects

G H Rose

Publications and source records attributed to G H Rose.

14 recordsLinked to original sources

Magnetic resonance elastography of skeletal muscle.

While the contractile properties of skeletal muscle have been studied extensively, relatively little is known about the elastic properties of muscle in vivo. Magnetic resonance elastography (MRE) is a phase contrast-based method for observing shear waves propagating in a material to determine its stiffness. In this work, MRE is applied to skeletal muscle under load to quantify the change in stiffness with loading. A mathematical model of muscle is developed that predicts a linear relationship between shear stiffness and muscle load. The MRE technique was applied to bovine muscle specimens (N = 10) and human biceps brachii in vivo (N = 5). Muscle stiffness increased linearly for both passive tension (14.5 +/- 1.77 kPa/kg) and active tension, in which the increase in stiffness was dependent upon muscle size, as predicted by the model. A means of noninvasively assessing the viscoelastic pro-perties of skeletal muscle in vivo may provide a useful method for studying muscle biomechanics in health and disease.

Animals↗

Medial or lateral mammographic lesions: down and out is down and out ... sometimes.

When there is doubt whether a mammographic lesion is medial or lateral to the nipple, the "down and out" rule is commonly employed. This states that a density moves inferiorly (down) on the mediolateral compared with the mediolateral oblique view if it is lateral (out) to the nipple. The author found areas in each breast, however, where the down and out rule does not apply.

Breast Neoplasms↗

Light-dark discrimination and reversal learning in early postnatal kittens.

During the early postnatal period kittens were trained in a visual discrimination task involving light-dark stimuli in order to determine the age of onset of visual control of learned behavior. A Y water maze was used with escape from water as the reinforcer. The results indicate that kittens are able to master the discrimination within the 5th week of life. The relevance of this result to electrophysiological measures of maturation is discussed.

Age Factors↗