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Biomedical subjects

G H Wilson

Publications and source records attributed to G H Wilson.

10 recordsLinked to original sources
PubMed1988

MR evaluation of early myelination patterns in normal and developmentally delayed infants.

This study demonstrates the ability of MR imaging to show progression of myelination in 64 infants and young children (ages 4 days to 36 months). T2-weighted spin-echo pulse sequences, frequently used for routine screening of intracranial disease, were used. Gray-white matter differentiation was seen in all patients, and changes occurring with age were documented. Three distinct patterns were seen, and age ranges were established for each pattern in developmentally normal children: (1) infantile (birth-6 months); (2) isointense (8-12 months); and (3) early adult (10 months onward). There was a statistically significant difference between the age ranges of the normal and developmentally delayed children showing all three patterns. These data should be helpful for identifying and following sequentially both infants with clinically suspected developmental delay and those with dysmyelinating or demyelinating disease.

Brain↗
PubMed1986

Magnetic resonance imaging of the brainstem and cranial nerves.

Ten normal human volunteers and 44 patients with pathology of the brainstem or cranial nerves were scanned using a. 3 Tesla permanent MR imaging system. MR images were obtained of the cranial nerves and brainstem using various spin-echo pulse sequences and scanning planes. 4 mm thick sections with .75 mm pixels on a 256 display matrix were used whenever possible. The normal MR images were correlated with thin section cryodissection specimens of fresh human cadavers. Brainstem structures including major nuclei and tracts were then identified. The cranial nerves were followed through the subarachnoid cisterns and the base of the skull. Pathological involvement of the brainstem by tumors, infarcts, and demyelinating disease was well shown and correlated with clinical findings. Examples of optic glioma, fifth, eighth, and twelfth nerve schwannomas as well as other cranial nerve pathology were also demonstrated. Magnetic resonance produces excellent images of cranial nerves and brainstem with high contrast resolution. Unlike CT, there is no beam hardening artifact from bone. T1 weighted images maximize brainstem-CSF contrast and are useful for demonstrating the external anatomy of the brainstem and cranial nerves. The T2 weighted images show internal brainstem anatomy, CSF within neural foramina, and highlight many pathological conditions.

Adult↗
PubMed1978

Giant intracranial aneurysms simulating brain neoplasms on computed tomography.

Giant intracranial aneurysms (GIA) may simulate brain neoplasms on computed tomography (CT) scans. We present three cases in which a GIA was mistakenly diagnosed as a brain neoplasm on the basis of CT findings. The correct diagnosis was made in each case by cerebral angiography. The possibility of GIA must be considered when a nonenhanced CT study shows a well circumscribed mass without edema at the base of the brain and contrast infusion reveals homogeneous or inhomogeneous enhancement.

Adult↗
PubMed1977

Computed tomography in intracranial cysticercosis.

The computed tomography (CT) scans and other radiographic studies of 23 patients with cerebral cysticercosis were reviewed. Parenchymal calcifications, the most common finding, are somewhat better seen on CT scans than on skull films. Ventricular cysts may be suspected by disproportionate enlargement of the involved ventricle. Cysts in subarachnoid cisterns are best detected by performing both CT and pneumoencephalography. Contrast enhancement was not seen with cisternal or ventricular cysts but may be with parenchymal cysticercus lesions.

Adult↗
PubMed1976

Contrast enhancement by arterial perfusion during computerized tomography.

Contrast enhancement of computerized tomography is usually performed by means of intravenous injection of iodinated contrast materials. The authors have utilized a technique of direct arterial infusion of iodinated contrast material supplying intracranial arteries during computerized axial tomography. A representative case is presented with comparison scans which were obtained without contrast enhancement and with conventional intravenous infusion of contrast. Marked improvement of the enhancement was clearly demonstrated in this case, with abnormalities readily defined that were not seen with the conventional intravenous enhancement procedure.

Cerebellopontine Angle↗
PubMed1976

Catheter technique for encephalography.

A catheter technique for encephalography utilizing a polyethylene catheter is described. The advantages are principally that it reduces the possibility of needle displacement during examination and thus the danger of extra-arachnoid injection of air.

Catheterization↗
PubMed1976

Accuracy of scanning, angiography and encephalography in posterior fossa tumors.

A material of 120 cases with posterior fossa tumors examined with scanning, vertebral angiography and encephalography was reviewed to determine the value of the information and accuracy these methods provide. Encephalography was the most accurate procedure (98% positive) compared to angiography (81%) and scanning (44%).

Brain Neoplasms↗
PubMed1975

Neuroradiology of the sphenoidal region.

The neuroradiological techniques employed in diagnosing a series of 54 lesions involving the superior orbital fissure and cavernous sinus (sphenoidal region) were reviewed in order to compare the value of sphenoidal tomography, pneumoencephalography, cerebral arteriography and sphenoidal venography. The patients included in the series exhibited clinical syndromes of sphenoidal region cranial nerve deficits. Confirmation of the sphenoidal region disorder was obtained in all cases. Of the four procedures, sphenoidal venography and basal tomography yielded the highest rate of positive studies.

Aged↗
PubMedDate not supplied

Clinical comparison of three contrast agents used in cerebral angiography.

A total of 139 cerebral angiograms were performed on patients assigned randomly to three groups. The contrast agents used for these groups included meglumine calcium metrizoate, meglumine diatrizoate and meglumine sodium diatrizoate. Pulse rate and blood pressure readings were taken preceding and following injections and pain and heat sensations were graded. There were no significant differences in incidence of nausea or in changes of blood pressure or pulse rate, or in severity of heat sensations. There was a lower incidence of severe injection pain with meglumine calcium metrizoate than with meglumine sodium diatrizoate.

Blood Pressure↗