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Biomedical subjects

G Höllerl

Publications and source records attributed to G Höllerl.

At least 19 recordsLinked to original sources

[10 years of endoscopy at the University Department of Surgery in Graz].

The results of the endoscopies carried out from 1973 to 1983 at our hospital are reported (6947 gastroscopies, 2189 colonoscopies). Gastroscopic aftercare following gastric resection for benign gastric disorders and after partial gastrectomy for carcinoma is discussed. The results of the use of laser in emergency endoscopies are presented (731 patients with 827 bleedings lesions). By implementation of laser there was a remarkable reduction in the rate of immediate and early operation and in early mortality in cases of gastrointestinal bleeding. The results of 244 endoscopic polypectomies are reported.

Aftercare↗

[Treatment of the injured spleen with fibrin glue, infrared contact coagulation and laser coagulation. An experimental study].

Experimental studies of hemostasis of the traumatised spleen are reported. After experimental trauma, rapid intraoperative hemostasis and subsequent preservation of the spleen was achieved by the use of a homologous fibrin glue system. A collagen fleece or an autologous fascial flap was used as a carrier for the adhesive mixture. Moreover hemostasis was also attempted with an infrared contact coagulation device and a Neodym-YAG-Laser. After fibrin gluing all the substances used are quickly absorbed by the organism. This is one of the major advantages of the fibrin adhesive method. When the bleeding surface was covered with a collagen fleece or a fascial flap, hemostasis was attained quickly. The collagen fleece has an absorptive effect which improves the hemostatic quality. Hemostasis with infrared coagulation is based on infrared light and on mechanical tissue compression. Possible pools of blood can be managed by compressing the contact surface. With this method, too, hemostasis can quickly be achieved. It was impossible to attain equally positive results with the contact-free laser device. Hemostasis is caused by a burn necrosis with the coagulation methods. The tissue healing process lasts until the necrotic tissue has been absorbed.

Blood Coagulation↗

[Infrared contact coagulation for hemostasis in liver and spleen].

With infrared contact coagulation (ICC) hemostasis of hepatic and splenic tissue is achieved by coagulation and mechanic compression of the bleeding surface. Thus, an eventual loss of energy due to a thick layer of blood can be avoided. After coagulation, the anti-adhesive effect of the cap of the ICC device prevents fresh bleeding. After experimental incisions on liver and spleen of various animal species hemostasis could be achieved quickly by application of ICC. Postoperative observation and histologic investigations were carried out until the 80th postoperative day. Hemostasis was observed in all cases, there were no signs of recidivant bleeding at relaparotomy. A slow absorption f necrotic tissue was observed. This could be a disadvantage regarding long term wound healing.

Animals↗

[Shock-treatment in gastro-intestinal-bleeding with 3,5% isocyanate crosslinked polypeptide solution].

In a prospective study infusions of 3,5% isocyanate crosslinked polypeptide solution 500 ml (Haemaccel 3,5%) were given to patients with gastro-intestinal-bleeding for shock treatment and prophylaxis. The increase in intravascular volume was always satisfactory. We did not see any undesirable side effects (anaphylaxis, anaphylactoid reaction, coagulopathy, oliguria).

Gastrointestinal Hemorrhage↗

[Hemostasis in the liver induced with tissue glue - comparison of 2 glue-component combinations].

After experimental hepatic resection in rabbits and piglets, haemostasis was achieved by using two types of tissue glue - fibrin glue and gelatin-resorcin-formaldehyde glue (GRF-glue). With both glues, an elastic adhesive film could be produced. Fibrin glue was completely absorbed by granulation tissue at the 11th postoperative day. After using GRF-glue a toxic necrosis and a subsequent demarcation of necrotic tissue could be observed, with the adhesive substance being not absorbed after 11 days. When used together with a collagen fleece, fibrin glue was not spilled away by tissue haemorrhage. Therefore it seems to be especially suited for haemostasis on the liver. With both glues, no leakage was observed after raising the portal vein pressure to 300 mm Hg during in vitro experiments.

Animals↗

[Prophylaxis and therapy of colon perforation in diagnostic fiber colonoscopy (author's transl)].

Three cases of colonic perforation which we could observe in 622 own colonoscopies and two which have been referred to us for surgical repair, are reported. On behalf of these cases the cause of such a perforation as a complication of colonoscopy is pointed out. The symptoms of colonic perforation are not very impressive and somewhat incharacteristic. The treatment of choice is immediate laparotomy, whereby the decision whether simply suture of the defect or resection with or without colostomy remains to be made intraoperatively. In case of massive pneumoperitoneum the puncture of the lower abdomen can be made as an emergency operation.

Adult↗

[Gastroscopy after gastric operations (author's transl)].

Gastroscopy after surgery of the stomach gives exact information about functional and morphological alterations. The aim of gastroscopy is to detect complications of the early postoperative period as well as of the later phase. Early diagnosis of gastric carcinoma after partial gastrectomy for benign lesions is only possible by routine gastroscopy.

Gastroscopy↗

[Blunt renal trauma: diagnosis, therapy and possible complications].

223 cases of blunt renal injuries, which were observed over a period of 19 years at the department of Surgery, University of Graz, are presented in this study. The value of several diagnostic procedures and the therapy are discussed in respect of early and late complications and the literature reviewed.

Adult↗

[Gastroscopy -- a routine procedure in the investigation of diseases of the stomach (author's transl)].

After a short review of the development of endoscopic investigations, the technique of gastroscopy is described and the indications for this procedure are pointed out. This procedure is of equal importance as radio-diagnostic measures in the routine investigation of stomach diseases and is of particular value when used as an emergency procedure and in the follow-up of patients after gastric operations. It also offers great advantages in the diagnosis of stomach tumours since biopsy material can be obtained from the lesion. Stomach haemorrhage due to gastric erosion, oesophagitis and the Mallory-Weiss syndrome are best diagnosed by gastroscopy. There are practically no contraindications to gastroscopy. The only precluding factor being an uncooperative patient. It is not contraindicated in patients with oesophageal varices or deformity of the spinal column. Complications are very rare. In the case of emergency gastrocscopy, shock must be counteracted and the blood pressure normalized before the investigation can be performed.

Emergencies↗