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Biomedical subjects

G Haig

Publications and source records attributed to G Haig.

7 recordsLinked to original sources

A double-blind comparison of mefenamic acid and piroxicam in acute soft tissue injuries.

Thirty patients suffering from strains, sprains or direct soft tissue injuries were entered into a double-blind trial comparing mefenamic acid and piroxicam. Mefenamic acid was given at a dosage of 500 mg 3-times daily and piroxicam as a single daily dose of 20 mg, for a maximum of 10 days. Both drugs were effective in treating the symptoms associated with acute soft tissue injuries. There were statistically significant improvements in all parameters monitored (pain, functional capacity, sleep disturbance, local swelling and tenderness) by Day 2, except for local swelling in the mefenamic acid group and sleep disturbance in the piroxicam group. By Day 5 all parameters showed improvement. Almost all (90%) of the patients had recovered from their injury in less than 1 week. Both drugs were well tolerated, only 5 patients reporting adverse events (3 on mefenamic acid and 2 on piroxicam).

Acute Disease

Portable thermogram technique for topically applied benzydamine cream in acute soft-tissue injuries.

A double-blind, parallel trial was undertaken with 3% benzydamine cream compared with a matching placebo, on patients suffering acute soft-tissue injuries. 21 patients received active material and 22 received placebo material. Patients applied the cream lightly 6 times a day for 6 days. Assessments were made (by the same physician) on days 0, 2, 4 and 6, and signs and symptoms were graded as "absent", "slight", "moderate" or "severe". Thermograms were taken on day 0 and day 6. The results showed significant relief of spontaneous pain, significant reduction in tenderness on pressure and in swelling on days 2, 4 and 6 of the trial, and a significant reduction in functional impairment on days 4 and 6, in the patients who had received the 3% benzydamine cream.

Administration, Topical

Lamb survival.

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Animals

Syme's amputation.

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Accidents, Traffic