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Biomedical subjects

G Heinecke

Publications and source records attributed to G Heinecke.

11 recordsLinked to original sources
PubMed1976

[Rise in serum creatinine under the androgen fluoxymesterone in chronic renal disease (author's transl)].

Eight men with chronic renal disease in the stage of compensated retention were given high doses of the androgen fluoxymesterone (40 mg/m2/day) for erythropoietin stimulation for 4 weeks. Seven of them showed a transient significant average rise in the serum creatinine level of 3.8 to 6.1 mg% which partly regressed only 8 to 12 weeks after stopping the medication. The rise in serum creatinine which appears under fluoxymesterone is attributable to a transient increase in the renal excretory function disturbance and/or a raised catabolism. Warning should be given against the further use of this drug in the treatment of renal anemia.

Adult↗
PubMed1976

Reversible encephalopathy following cephacetril therapy in high doses in a patient on chronic intermittent hemodialysis.

A patient on chronic intermittent hemodialysis at home showed signs of acute encephalopathy after an 8-day's treatment with a total dose of 78 g cephacetril (Celospor). Features included papilledema, loss of visual fields, severe generalized EEG changes and bilateral occipital abnormalities on a brain scintigram. Psychopathological findings consisted of a severe psychosis. The visual fields defects were the last sign of the encephalopathy to disappear.

Abscess↗
PubMed1975

Clinical value of the renal protein clearance determination.

The clinical applicability of the determiniation of selectivity in proteinuria in the traditional way is limited. The methodological apparatus has to be relatively completed to get predicative results. Simplified procedures, e.g. determination according to two proteins only, have not proven to be useful in our hands. Screening tests such as disc electrophoresis have to precede the determinations. In special clinical problems, e.g. the question of steroid sensitiveness in morphological forms of glomerulonephritis, which supposedly do not respond to steroids according to the results of prospective studies, or as a parameter in observing the follow up of a disease, protein clearances may be a valuable diagnostic help.

Adolescent↗