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Biomedical subjects

G Heron

Publications and source records attributed to G Heron.

14 recordsLinked to original sources

Twin channel infrared optometer for recording binocular accommodation.

A twin channel infrared (IR) optometer for recording accommodation from each eye is described. Some modifications to a conventional single channel optometer design are necessary to facilitate binocular recording. The optometer incorporates an on-line microcomputer for data acquisition and processing. Processing includes power spectrum and correlation analysis, and a facility for performing cursor controlled measurement of time delays. Accommodation responses recorded are shown to be independent of horizontal eye movements, and little affected by the drug used for mydriasis.

Accommodation, Ocular

Binocular accommodation reaction and response times for normal observers.

Accommodation was recorded from right and left eyes of visually normal observers in both binocular and monocular viewing. Reaction and response times were similar in monocular and binocular viewing and are not influenced by eye dominance. Far-to-near responses were significantly quicker than near-to-far responses. The origin of this difference may be a feature of the elastic properties of the accommodation mechanism. Limited data are presented that indicate that the slowing of accommodation speed with age affects the near-to-far response disproportionally. Errors in the initial direction of response were fewer in binocular viewing in comparison with monocular viewing.

Accommodation, Ocular

The Pulfrich phenomenon and its alleviation with a neutral density filter.

A case is described in which a presumed vascular accident resulted in long-standing visual difficulties in both reading and the analysis of vectors of moving objects. Clinical examination revealed minimal right optic atrophy with a relative superior altitudinal visual field defect associated with a positive Pulfrich effect. A partial head turn to the right in association with paresis of saccades and pursuit eye movements to the right was also evident. Spectacles for distance which incorporated a neutral density filter before the left eye were prescribed. These practically eliminated the Pulfrich effect and alleviated the problems of vector analysis. A near correction was provided which incorporated prisms with bases to the right. This eliminated the reading difficulties. The visual problems experienced by patients suffering from a positive Pulfrich effect are described and discussed.

Eyeglasses

Perceptual detectability of ocular accommodation microfluctuations.

When the eye fixates a stationary stimulus, the power of the lens is known to change rapidly and continuously. Although the basic characteristics of this fluctuating activity are known and the influencing factors have been identified, their exact role in the control of accommodation is uncertain. It is thought that, for the fluctuations to be useful, a detectable change in the retinal image is necessary, yet an accommodation response can be provoked by a stimulus change of only 0.1 D, well within the ocular depth of focus as conventionally measured. In this study we examine whether the fluctuations of accommodation are able to provide perceptual sign information or whether the presence of a sensorimotor mechanism utilizing subthreshold blur is required. Normal accommodation fluctuations for steady-state viewing were recorded using an infrared optometer and subsequently were used to drive a Badal stimulus optometer. The perceptual threshold of the fluctuation signal for an eye under cycloplegia was then determined. The threshold for the detection of the fluctuations at optimal focus was not significantly different from the root-mean-square value of the actual response. Hence a portion of the fluctuations more than spans the dead space (depth of focus) and is therefore capable of providing information to control accommodation without the need for a subthreshold mechanism.

Accommodation, Ocular

Fluctuations in accommodation: a review.

When a young observer attempts to accommodate steadily on a fixed stimulus, the nominally steady-state response shows small instabilities or fluctuations (sometimes termed microfluctuations or oscillations). These fluctuations typically have an amplitude of a few tenths of a dioptre and a frequency spectrum extending up to a few Hertz. The properties of these fluctuations are described for various viewing conditions: pupil diameter, target vergence, target form, target contrast, and target luminance all influence the frequency spectra of the oscillations, as may anomalies of vision such as amblyopia. The possible roles that the fluctuations might play in the function of the accommodative system are discussed. It is suggested that the higher frequency components around 2 Hz may arise from the mechanical and elastic characteristics of the lens, zonule and ciliary body. Components at lower frequencies (less than 0.5 Hz) may be of more significance in the function of the accommodative control system.

Accommodation, Ocular

Central visual fields for short wavelength sensitive pathways in glaucoma and ocular hypertension.

While conventional clinical visual acuity and kinetic visual fields may be essentially normal in ocular hypertension and early stages of glaucoma, other foveal aspects of vision (eg color, spatial and temporal contrast sensitivity) may be quite abnormal. Specifically, a selective vulnerability of the short wavelength sensitive (SWS) visual pathways in these conditions has previously been noted. Here we studied the central visual fields of 33 primary open angle glaucoma (POAG) patients, 32 ocular hypertensives (OHT), and 24 age-matched normal controls using blue and yellow test flashes on bright yellow backgrounds. SWS cone and MWS and/or LWS cone pathway sensitivities were measured at the fovea and at 2.5 degrees, 5 degrees, 10 degrees and 15 degrees eccentricities, in either the inferior temporal (for OHT) or horizontal nasal retina (for POAG). As expected, all groups had normal sensitivity to yellow flashes--detected by LWS and/or MWS cones--in these meridians. By comparison, for the blue flashes--detected by the SWS cones--the POAG and OHT groups had sensitivity deficits, uniformly across the central visual field, of about 6X and 1.8X, respectively, compared to normals. While six of 31 (19%) OHT subjects had localized glaucomatous field defects (greater than 0.4 log units) in the non-foveal inferior temporal retina, none of the 12 OHT subjects who were also tested in the horizontal nasal retina showed loss in this meridian. Finally, while no POAG subjects had localized sensitivity loss for yellow flashes in the horizontal nasal retina, four did show local field defects with blue test flashes.(ABSTRACT TRUNCATED AT 250 WORDS)

Aging

Clinical measures of central vision function in glaucoma and ocular hypertension.

A generalized loss of visual sensitivity, even for foveal targets, has been reported as an early sign of glaucoma. In the present study of central vision, we used relatively simple and rapid clinical tests of color thresholds, color discrimination, and spatial contrast sensitivity to compare the vision of three age-matched groups of patients who had primary open angle glaucoma (n = 33) or ocular hypertension (n = 32) as well as normal subjects (n = 24). The largest sensitivity losses for both glaucoma and ocular hypertensive groups were disclosed by a color threshold test with blue lights designed to isolate the blue-sensitive pathways of the visual system. The loss of sensitivity for both the glaucoma group and the ocular hypertensive group is consistent with recent reports (from postmortem studies of human eyes) of extensive axon death even in the absence of glaucomatous field defects.

Aged

Foveal and non-foveal measures of short wavelength sensitive pathways in glaucoma and ocular hypertension.

Blue-sensitive cone thresholds (the ability to detect blue test lights presented on a bright yellow background) were measured to examine foveal and central vision field sensitivity in groups of 33 glaucoma, 31 ocular hypertension (OHT) and 24 age matched normal subjects. Results showed these thresholds were substantially reduced (in all areas tested) for the glaucoma group (approximately 0.8 log units) and less reduced for the OHT group (approximately 0.2 log units), when compared to the normal group threshold. Measures of red-sensitive and green-sensitive cone thresholds showed no difference for all three groups. Furthermore, 16% of the OHT group showed visual field abnormalities for the blue-sensitive cone threshold measure. We conclude that efforts to detect early function loss in glaucoma and OHT could be improved using these measures in clinical practice.

Color Perception

Power spectrum analysis in the study of ocular mechanisms.

The use of power-spectrum analysis in the study of ocular dynamics is becoming increasingly widespread. This paper summarizes the key points of signal acquisition and power-spectrum analysis, emphasizing aspects which we have found to be of relevance when the technique is applied to experiments in binocular accommodation. The considerations and conclusions are relevant to other areas of investigation into ocular dynamics and similar biological systems.

Accommodation, Ocular

Stereoscopic threshold in children and adults.

The threshold of stereoacuity is reported as measured on 369 normal children aged 3 to 7 years, and on 51 normal adults. Four standard clinical stereotests were used and two different testing procedures adopted. The results show that both threshold and variability decrease with age, and performance becomes adult-like at different ages for different tests. Interest correlations are poor, and in cases where the correlation is significant, no identifiable pattern emerges between testing procedures, age, and stereotests. The procedures themselves gave no significant difference in stereoacuity values between all four tests.

Adult

Assessment of children's colour vision using the Pickford-Nicolson anomaloscope.

The colour vision of 439 boys, aged 4-11 years, was measured by the Pickford-Nicolson anomaloscope and four pseudoisochromatic tests. Matching range and dispersion of mid match point were found to be larger than adult values, but did not decrease with age. However, younger children took longer to establish matching range. Twenty-eight (6.4%) colour defectives were found and it is concluded that the Pickford-Nicolson anomaloscope gives valid results with children.

Age Factors

A simple infra-red optometer for accommodation studies.

The design of a continuously-recording optometer of minimal mechanical and electronic complexity is described. It operates on the Scheiner principle and has good time response for dynamic measurements. Theoretical and experimental studies show that linearity over an adequate range can be achieved by a suitable choice of system parameters; the response depends partly on Scheiner and partly on defocus effects.

Accommodation, Ocular