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Biomedical subjects

G Hillerdal

Publications and source records attributed to G Hillerdal.

117 records · Page 7Linked to original sources
PubMed1979

Rheumatoid arthritis, immune complex disease, and hypereosinophilic syndrome. Report on a case.

A patient with typical rheumatoid arthritis is presented. After a short period of the disease a hyperosinophilic syndrome (HES) developed with vasculitis, pulmonary fibrosis, and thrombosis, and the disease took a malignant course. The patient died within a year after the diagnosis of HES. High titres of rheumatoid factor were manifested and total complement (CH50) was very low, indicating an active immune disease. As HES has been suggested to have an autoimmune aetiology, these findings are interesting, as positive rheumatoid serology has very rarely been reported in patients with this syndrome.

Arthritis, Rheumatoid↗
PubMed1979

Intrathoracic goitre with the superior vena cava syndrome, hoarseness and acute stridor.

A 69-year-old man presented with acute stridor and was found to have the superior vena cava syndrome and bilateral laryngeal paresis. A clinical diagnosis of malignancy was made, but before any definite investigations could be made an emergency operation had to be performed to relieve the trachea. On operation the patient was found to have a benign goitre. The literature on the subject is discussed. Since the great majority of cases with the superior vena cava syndrome is caused by malignant diseases, it has been suggested that in acute cases radiation therapy should be started without a microscopic diagnosis if necessary, but such a practice must be warned strongly against.

Aged↗
PubMed1979

Occupation and bronchial carcinoma.

All patients newly diagnosed as bronchial carcinoma were studied during a 5-year period. There were 212 male and 61 female patients. A careful occupational history was taken and the occupations of the patients in 1950 were compared with the County's official occupational statistics of that year, and their chest X-rays were scrutinized for pleural plaques. A significantly higher proportion of metal workers and workers from the building industry was found among the patients, while agricultural workers were under-represented. Smoking habits did not explain the difference. The number of patients with pleural plaques was four times higher than expected. It is concluded that dust in certain occupations has an additive effect on the carcinogenic effect of smoking.

Adult↗
PubMed1978

Pleural plaques in a health survey material. Frequency, development and exposure to asbestos.

All cases of pleural plaques discovered at mass X-ray screening in Uppsala County during 1970-1976 were collected. Case histories, including the history of exposure to asbestos and smoking habits, were taken. A total of 508 cases, 492 males and 16 females, were found. Eighty per cent were smokers, which was more than expected, and 80% confirmed exposure to asbestos. The frequency of pleural plaques was found to increase steadily with the years parallel to the increase in the use of asbestos which had started 30 years earlier. The pleural plaques showed gradual development and many finally calcified.

Adult↗
PubMed1978

Abdominal aortic aneurysm in homocystinuria.

The first reported case of abdominal aortic aneurysm complicating homocystinuria is presented. The clinical features and microscopic findings were identical to those of an atherosclerotic aneurysm. Homocystinuria may stimulate Marfan's syndrome but can be differentiated by the cyanide-nitroprusside screening test for homocystine in urine. Although homocystinuria is accompanied by an increased risk of thrombosis, surgical treatment of complicating diseases should not be avoided. Pyridoxine treatment is recommended.

Adult↗
PubMedDate not supplied

Value of the lateral view in diagnosing pleural plaques.

To assess the value of the lateral view in the diagnosis of pleural plaques, 2018 chest roentgenograms from the general population were scrutinized for such plaques. The lateral and posterior-anterior (PA) views were read separately and without knowledge of the occupational history or other clinical data. Of the males, 4.8% had pleural plaques in the PA view and 2% had dorsal pleural plaques in the lateral view. A total of 54% of the positive cases in the PA view also showed dorsal plaques in the lateral view, while 69% of those with dorsal plaques also showed typical plaques in the PA view. Thus, there remained a number of cases which were diagnosed only in the lateral view; in all, these constituted 18.8%.

Asbestosis↗
PubMedDate not supplied

Idiopathic diaphragmatic paralysis and asthma bronchiale.

A 38-year-old man suffered from chronic asthma. He also had paralysis of the right diaphragm which had been present for some years. During an acute asthmatic attack following administration of acetyl salicylic acid, a chest roentgenogram revealed hyperinflation of the lungs, especially of the right side. The paralytic diaphragm was pushed down considerably. After treatment of the acute attack of asthma, the diaphragm ascended to its 'normal' place. This case illustrates 'air trapping' in acute asthma and sheds some light on the mechanism behind it, which is discussed.

Adult↗