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Biomedical subjects

G Hohenberg

Publications and source records attributed to G Hohenberg.

At least 37 records · Page 2Linked to original sources
PubMed1986

[Radiologic breast diagnosis following breast-preserving operations and radiation].

The postoperative and post-irradiation changes occurring in the female breast that can be recorded via mammography, were demonstrated in 74 patients with carcinoma of the breast in the T1 and T2 stages after partial resection and postoperative irradiation. 47 of these women received exclusively percutaneous treatment, whereas 27 received combined treatment both percutaneously and interstitially. The changes occurring in the cutis and in the mammary gland tissue were analysed in respect of first and follow-up examinations. Problems of differential diagnosis were discussed and demonstrated.

Brachytherapy↗
PubMed1985

[Prognostic factors in the treatment of inoperable orofacial tumors with simultaneous radiotherapy and intra-arterial chemotherapy].

Between January 1973 and April 1982 66 evaluable patients with advanced inoperable orofacial tumours underwent intraarterial Bleomycin and Methotrexate with simultaneous radiotherapy in a prospective study. 32 patients had no previous treatment, 34 patients had initial surgery, radiotherapy and/or chemotherapy. 15 mg Bleomycin were administered through a catheter into the arteria externa carotis daily in the morning. 25 mg Methotrexate were given in the same way at night followed by 3 mg Calcium-Leucovorin i.m. every 8 hours. The cumulative dose was 300 mg Bleomycin and 500 mg Methotrexate. Four hours after the administration of Bleomycin the target volume was irradiated (single fraction 2 Gy, total dose 60 to 65 Gy). The overall response rate was 65% containing 17% complete and 48% partial remission. Destruction of the bone appeared to be the most important index at the start of the therapy. Further prognostic determinants as previous treatment, localisation of the primary tumours (maxilla and mandibula respectively oral cavity and oropharynx) and local regional lymphnode stage missed statistically significance in the survival time, may be due to a possible radiosensitizing effect of the simultaneous chemotherapy. Complete remission turned out to be the most important prognostic factor after the end of treatment. Patients responding with complete remission show a median disease free survival of 56+ months and a median survival time of 82 months. Acute reactions were reversible. Only in 14% of the patients the treatment could not be finished. Better results could be obtained by electron-affinic radiosensitizers and high LET radiation.

Antineoplastic Agents↗
PubMed1984

[Patho-anatomy of lymph vessels of the liver from a roentgenologic viewpoint].

With increased formation of lymph the lymphatic vessels of the liver are detectable on X-ray and can be assessed. Lymphatic vessels of the portal areas and Glisson's capsule and the pathways of the efferent extrahepatic lymphatics are described. Examples of pathological hepatograms in cirrhosis are presented.

Adult↗
PubMed1984

[Indications and methods of megavolt therapy in prostatic cancer--evaluation of 98 cases].

A report is given on 98 unselected cases of carcinoma of the prostate, treated at the University Department of Radiotherapy and Radiobiology of Vienna from January 1974 till December 1979. 85% of the patients were over 60 years old. More than the half of them had been subjected to surgery or had undergone hormone therapy before starting radiotherapy. Moreover, more than 50% of the patients showed advanced disease (stages C or D). Local control was achieved in about 95% of cases. Long-term side effects such as irradiation damage to bladder or gut occurred in about 5% patients only. Survival rate was 75.5% after 3 years, 66.7% after 5 years and 46.7% after 7 years. Recommendations as to the management of such an unselected patient group are given. Our modified radiation technique is presented.

Aged↗
PubMed1984

[Parenchyma pattern and breast cancer. Analyses and consequences].

500 mammograms were analysed according to Wolfe, with additional mastography group. The mammogram documented a risk pattern which correlated to the statistic increase in carcinoma. Our own experience also showed no correlation between simple mastopathy and carcinoma of the breast. Therefore, the risk pattern should be regarded as part of the known risk factors and should indicate selective screening at a yearly interval, even if clinical examinations are negative.

Adult↗
PubMed1984

[Mammographic and sonographic appearances of traumatic changes in the female breast].

As a result of trauma, or surgery, haematomas develop which are visible and can be demonstrated by sonography; they either regress completely or leave circular foci after a period of days or weeks. Both the new and older lesions can usually be well shown by sonography. During these stages the sonogram may be valuable. Long-standing changes, such as fat necrosis, are best shown by mammography. There are three types of fat necrosis; oily cysts, mixed types or scarring leading to an appearance resembling a carcinoma. Oily cysts may undergo mural calcification leading to liponecrosis macrocystica or liponecrosis microcystica, depending on size.

Adult↗
PubMed1984

[Differential diagnosis of saddle-like formations in the gastric fundus].

X-ray examination of the stomach sometimes shows a saddle-like impression of the region of the fundus. This phenomenon is without any clinical importance, but there are many diseases such as hiatal hernia, benign and malignant tumours, inflammatory diseases, and varices which are localised at the fundus. Differential diagnostic problems are discussed.

Diagnosis, Differential↗
PubMed1983

[Mammographic changes in the partially resected and irradiated breast].

Thirtyseven patients with breast cancer stage T1 have been treated by tumorectomy or quadrantectomy and radiation therapy. Mammographic changes as skin thickening and parenchyme reaction were described and put in correlation between the end of treatment and mammography controls. Differential diagnostic problems are discussed.

Adult↗
PubMed1983

[Sonographic determination of the irradiated pulmonary volume in case of irradiation of the thoracic wall].

In order to determine the irradiated pulmonary volume, comparative examinations by sonography and computed tomography were made in ten patients submitted to postoperative radiotherapy for mammary carcinoma. The physical and anatomical conditions of sonographic volumetry are discussed. In all cases irradiated with tangential contralateral fields, the irradiated pulmonary volume was less than 200 ccm (118 ccm on an average). The sonographic results did not differ essentially from those of computed tomography, so that the sonographic examination can be offered as a simple and sufficiently precise method of documentation within the frame of an individual therapy planning.

Breast Neoplasms↗
PubMed1983

[Optimization of dose distribution by use of lead wedge filters in combined electron and photon therapy].

A significantly improved isodose distribution has been reached by the combined application of high-energy photons and electrons, however, there are still problems with respect to the critical organs. It was demonstrated that a considerable progress is possible by the use of lead wedge filters within the frame of this irradiation technique. Recommendations for clinical application are given on the basis of the authors' own practical experiences.

Electrons↗
PubMed1983

[Roentgenologic analysis of deglutition--evaluation of 231 cases].

The act of swallowing, which can be analysed by means of radiologically well-discernible phases, is described and placed in anatomic correlation. Several items are of essential importance for regular swallowing: the ability to close the lips, the isthmus faucium, epipharynx and epiglottis and also the action of the lingual punch and the involuntary phase of the act of swallowing induced thereby. During the first phase--the voluntary oral phase--the bolus is prepared for swallowing and the oral cavity is separated from the oropharyngx by the closed isthmus faucium. In the second--the oropharyngeal phase--the involuntary part of the act of swallowing is triggered and the entrance to the nasopharynx is closed. The bolus gets pressed into the oropharynx. During the last, the pharyngo-oesophageal phase, the bolus enters the cranial part of the oesophagus, while crossing the respiratory tract. This step is secured by several mechanisms against the danger of aspiration. Evidence for the occurrence of physiological aerophagia is supplied.

Adolescent↗
PubMed1982

[Percutaneous radiotherapy of thyroid malignancies. Analysis of 54 cases].

A report is given on 54 cases of thyroid malignancy treated at the University Department of Radiotherapy and Radiobiology of Vienna from January 1970 till September 1977. These cases are analysed according to local control of disease and survival time. The 5-year disease-free survival rate for all histological types was found to be 48%. Local recurrence occurred in 13% of cases. Combined external irradiation and radioiodine therapy is critically discussed.

Bone Neoplasms↗
PubMed1982

[Radiotherapy in nasopharyngeal cancer. Evaluation of 37 cases].

37 cases of nasopharyngeal tumors were studied which have been treated from January 1971 through December 1976 at the University Clinic for Radiotherapy and Radiobiology Vienna. These cases were analysed according to local and regional control and survival time. The 5-year-disease-free survival rate for all patients studied is 46%. Local and regional recurrences are discussed.

Adult↗