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Biomedical subjects

G Hole

Publications and source records attributed to G Hole.

At least 37 records · Page 2Linked to original sources

Delusional depression and suicide.

After a short survey of the relevant literature, the authors discuss the significance of delusional depression symptoms for suicidality, whereby they do not regard such symptoms alone as a sufficient condition for classifying a delusional patient as suicidal. In a comparison of delusional depressed patients with a non-delusional control group (matched pairs), the former were adjudged to be significantly less suicidal than the control group and did not differ from the control group in regard to suicide frequency.

Delusions↗

Double-blind study of oxaprotiline versus clomipramine in the treatment of depressive inpatients.

In a double-blind study on 38 unselected depressive inpatients (19 per group) suffering from endogenous and psychogenic depression, oxaprotiline, a new tetracyclic compound, a hydroxylized maprotiline with a highly selective norepinephrine reuptake inhibition, was compared with clomipramine over a period of 28 days in a daily dosage of 150 mg. Both drugs were found to be approximately equivalent and with no significant differences due to the overall assessment of the reduction of depression severity and amelioration of goal symptoms. This was also reflected in the results of the Hamilton Depression Scale and the self-rating scales for depression (SDS, Bf-S, ESTA).

Adult↗

Advantages and disadvantages of special depression treatment and research wards.

After the establishment of the first European depression research ward at the PUK Basle 1968 we started the Weissenau 'depression treatment and research ward' in 1976. Since this time there were approximately 1800 admissions of depressed inpatients. Up to this day 3 of the county mental hospitals of Baden-Württemberg FRG (1984 2797 depressive inpatients, average time of stay 49 days) established also such special treatment wards. The conceptualization of depression wards due to treatment strategies is still in the beginning and based on clinical experience up to now. Some advantages of such depression wards could be treating a homogeneous group of patients, the chance for special psychotherapeutic treatment strategies (reinforcement of non-depressive behaviour, empathic understanding of underlying dynamics), reduced anxiety in dealing with suicidal and clinging patients, a better dealing with regressive tendencies, or also better conditions for research programmes. Some of the disadvantages could be an uncontrollable regression under too empathic conditions or an accumulation of severely depressed which can paralyze therapeutic activity. To realize such a psychotherapeutic and pharmacological treatment and research program it is necessary to have staff members specialized and also supervised in dealing with depressed patients.

Combined Modality Therapy↗

[Diagnosis of mania. Disease picture and its psychological, physical and social sequelae].

While depression is a commonly discussed condition, mania is rarely mentioned. Subjectively, this disorder is associated with less incapacitating complaints, but it may have a more troublesome effect on the patient and the people around him than most mental illnesses. This article therefore presents a practice-oriented overview of the manic syndrome and its consequences: the term, its definition, age and sex distribution, mental and physical symptoms, psychosocial consequences, aspects of differential diagnosis, information for relatives and the family doctor, aspects of criminal and civil law, are discussed.

Adolescent↗

[The reaction of mental patients to medical diagnosis].

According to the results of a social psychiatric research on hand of reflected image transformulated questionnaire for clinical healthy persons and hospitalized patients the following result is: 9/10 of all registered laymen are afraid of dramatic scenes (manifold naming). In each second case such a situation however happens obviously extensive deactivated. More than five times of the shocked persons as healthy respondents refuse at these questions a comment. But in laymen circles they believe double till three times so frequently in sadness and desperation respectively revolted rebel of the patients. In reality you can find very often the still resignation or the facilitated acceptance of the necessary steps. The more simple the origin class the more exists resignation or cooperation. In reverse rebel, depressive reaction and desperation again continuously on relevance due to the medicine diagnosis from the primary to the upper class. Depressives react sadly and desperatedly as well as female maniacs. People who are free from alcohol will have found the expected silence. The schizophrenes as well as the male maniacs seem to rebel revolted.

Alcoholism↗

[Clinico-experimental study of daily variations in depressed patients].

Forty hospitalized depressive patients of both sexes with primary depressive syndrome and concomitant diurnal variations were investigated at defined times with the following method: special questionnaire on subjective evaluation of depressive diurnal variation (TSF), mood scale (Bf-S of v. Zerssen), Necker cube, tests of autonomic function (amount of saliva and circulatory variables), global assessment of the depth of depression.--The quantitative differentiation into diurnal variations of different extents undertaken by means of the TSF were validated by the daily difference of the Bf-S. Between the extent of the depressive diurnal variation and the nosological group as well as the depth of depression no relationship could be found. Also the rate of turning over the Necker cube did not show any alteration in the diurnal rhythmicity. On the other hand, the inverse diurnal rhythmicity of the amount of saliva, also according to the corresponding results in the literature, can be interpreted as influence of the depressive diurnal variation. The resting values of pulse rate and blood pressure followed the diurnal physiological rhythm, but in addition they revealed a quantitative influence of the depressive diurnal variation (amplification). No systematic influences could be demonstrated for the orthostatic values.--The results show that in this methodological procedure only a few variables could be demonstrated to be associated with the depressive diurnal variation. On the other hand, it could be proved that not only mental but also certain autonomic components of the depressive syndrome undergo an alteration with the depressive diurnal variation.

Adult↗

[Politics and mental disease. How great are the chances of success of candidates who had been treated for mental disease?].

"Would you vote for a politician who is said to have been mentally ill?" This question was asked of 554 psychiatric in-patients and an unselected collective of 1282 clinically healthy persons. About two thirds of the patients and about twice the number of the healthy persons interviewed do not see in a past psychiatric disorder a hindrance to a political career. But every fourth patient and more than half of the laity - a decisive criterion for successful election - rejected this proposal categorically. Such a candidate could expect the lowest number of votes from older persons, married or widowed, rural communities, and the majority of voters, i.e. of the middle and lower classes. It cannot be excluded that the recent case of Thomas Eagelton in the USA may find its counterpart in Germany.

Humans↗

[Depressive patients in institutional treatment. 1st results of an epidemiologic study of the Weissenauer Depression Ward].

Between the end of 1976 and the beginning of 1980 more than 700 patients were admitted to the Weissenau Depression Ward. The most important data were obtained by way of special questionnaires, and part of it will be presented in abridged form in the following paper. In respect of the distribution of sex and age, marital status, manner and background of admission, psychiatric case history, duration of hospitalization, nosological allocation, above all for the nature of depression, age, phenomenological and nosological distribution, course of illness, time of hospitalisation, and therapeutical success interesting information is gained.

Adolescent↗