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Biomedical subjects

G Hombergen

Publications and source records attributed to G Hombergen.

5 recordsLinked to original sources

The Groningen, Nijdam and Provox voice prostheses: a prospective clinical comparison based on 845 replacements.

The Groningen, Nijdam and Provox voice prostheses (VP) are all low-pressure, indwelling voice prostheses. Although there are differences concerning the valve mechanism, they have a similar design and are therefore interchangeable. In a prospective study, 845 consecutive replacements were evaluated in 158 patients. Average device lifetime differed significantly from 13 weeks for the Provox VP and 15.8 weeks for the Groningen VP, to 19 weeks for the Nijdam device. Leakage through or around a voice prosthesis was the main replacement indication. Leakage occurred significantly more often with the Provox VP (80.2%) than with the Groningen VP (58.8%) or the Nijdam VP (55%). Increased airflow resistance as a replacement indication occurred significantly more often with the Groningen VP (45.4%) and the Nijdam VP (45.9%) than with the Provox VP (22.7%). Complications during the replacement procedure were rare and usually mild. Replacement was usually an easy outpatient procedure; general anaesthesia was only necessary in 3.0% of 845 replacements, without any significant difference between the three devices. Granulation tissue and hypertrophic scar tissue formation were the most frequent local complications. They occurred in less than 10% of our patients but were significantly more common in patients with a Nijdam VP.

Airway Resistance↗

Relations between audiometrical thresholds of potential cochlear implant patients and their performance in preoperative psycho-physical tests with electrical stimulation.

Part of our selection procedure for cochlear implant candidates is the preoperative electrical stimulation of the cochlea. With a transtympanic needle, placed as closely as possible to the round window, the dynamic range for a number of frequencies is measured and a frequency identification test and a temporal difference limen test are carried out. Our first series of preoperative tests suggests a relationship between the audiometrical pure-tone thresholds, the dynamic range of electrical stimulation and the performance on the temporal difference and frequency identification test. For the preoperative electrical stimulation tests, a relatively good pure-tone average may indicate a wide dynamic range, a short temporal difference limen and a high score in the frequency identification test.

Audiometry, Evoked Response↗

The application of evoked potentials in the diagnosis and follow-up of children with intracranial tumors.

Somatosensory and brainstem auditory evoked potentials (SSEPs and BAEPs) provide sensitive measures of the central conduction functions of the auditory and somatosensory input systems at different levels of the central nervous system. The contribution of SSEPs and BAEPs in the primary diagnosis and follow-up of 26 children with infra- and supratentorial tumors were reviewed. The SSEPs, especially the specific complex, showed a latency increase in patients with supratentorial and brainstem mass lesions involving directly or distantly the somatosensory tracts. The BAEPs were sensitive for supratentorial pressure effects and for local and distant posterior fossa tumor effects. In the follow-up of children, evoked potentials offer a good method of detecting tumor recurrence, whereas neuroradiological procedures may be obscured by surgical or radiation artifacts.

Adolescent↗

[Normal values in brain stem electric response audiometry (BERA)].

The normal values in brainstem electric response audiometry (BERA) were studied. A description is given of the latencies and amplitudes of the normal response. The effects of (1) the intensity of the stimulus, (2) the stimulation rate, and (3) the use of a sedative were investigated. It seems that the transmission time P1-P5 is significantly longer (+/- 0.25 msec) in men than in women.

Audiometry↗