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Biomedical subjects

G Hussain

Publications and source records attributed to G Hussain.

8 recordsLinked to original sources

An infrared study of co-adsorption of N2O and CO on ZnO.

The absorption of N(2)O and CO at room temperature on finely divided ZnO surfaces gives reversible absorption bands from surface N(2)O species in the 2237-2245, 2265-2285 and 1245-1255 cm(-1) regions. The growth of the first band is at the expense of the second while its intensity and position depends on the extent of the surface carbonate, formed by the oxidation of CO by N(2)O. The order of introduction of CO and N(2)O, and whether the ZnO surface is oxidised or reduced, gave significantly different results in terms of carbonate formation. The strongest carbonate formation and implied decomposition of N(2)O, occurs at room temperature when CO is added to preadsorbed N(2)O on an oxidised ZnO surface. A single bidentate carbonate is formed under these conditions but on heating in the gas mixture to 200 degrees C an additional, possibly monodentate, carbonate occurs together with a surface formate species.

Adsorption↗

Depressor labii inferioris resection: an effective treatment for marginal mandibular nerve paralysis.

In patients who show their lower teeth during smiling and facial animation, paralysis of the marginal mandibular nerve (MMN) causes a noticeable asymmetry of the lower lip due to the absence of depressor function. This paper presents a balancing technique for this lower lip asymmetry that involves resection of the depressor labii inferioris (DLI) on the nonparalysed side. The anatomy of the muscle, the operative technique, and the effectiveness of the procedure are outlined. A retrospective chart review was performed for 42 adult patients who were treated for MMN palsy with a DLI resection. Seven cases had only the MMN involved, and 35 cases had unilateral facial nerve paralysis. Thirty-six of these patients were available for a follow-up telephone survey. Of the 42 primary DLI resections performed, 36 cases had successful outcomes. Of the six patients who failed to achieve the expected results, five patients had repeat DLI resection and three of these achieved the desired result; the other two patients required a third resection. One patient continued to have DLI action with smiling and subsequently had a Botox injection into the DLI with good results. Of the 36 survey respondents, 21 patients felt their lower lip was asymmetrical at rest prior to DLI resection and 18 of these patients were improved by the procedure (P = 0.0001). Twenty-nine of the 36 patients reported that their lower lip was more symmetrical when they smiled following the DLI resection (P < 0.0001). The bilateral lack of movement in the lower lip when expressing emotions, such as anger and sorrow, was not as important to the patient as the lack of symmetry when expressing these emotions. Patients' speech either improved or showed no change, the amount patients bit their lower lip significantly improved (P = 007) whereas oral continence showed no significant changes (P = 0.147) following the DLI resection. DLI resection is a simple and effective procedure for the treatment of MMN palsy. The results are permanent and predictable. Lower lip symmetry is produced both at rest and with facial animation, without causing a functional deficit. The expected results of surgery can be trialed by local anaesthetic or botulinum toxin to block the activity of the DLI.

Adult↗

Comparison of cortical adrenergic, cholinergic and benzodiazepine receptors between albino rat and desert rat (Mastomys natalensis) using radioreceptor binding.

Cortical alpha-adrenergic, beta-adrenergic, cholinergic (muscarinic) and benzodiazepine receptors have been studied in the albino rat and Mastomys natalensis (desert rat) using radioligand binding. Scatchard analysis was performed to determine affinity (Kd) and density (Bmax) of receptors. Compared to the albino rat, the desert rat was found to have higher affinity and density of alpha-adrenergic receptors. Beta-adrenergic receptors had similar Kd in both species but Bmax was significantly lower in the desert rat as compared to the albino rat. Cholinergic (muscarinic) receptors as well as the benzodiazepine receptors were in significantly higher density in the desert rat. The affinity was low for muscarinic receptors in the desert rat but equal for benzodiazepine receptors in both species. Since there are more alpha-adrenergic, muscarinic and benzodiazepine receptors in the desert rat, this species should be of value in screening compounds active at these sites.

Animals↗

Crisis intervention in an emergency setting.

The situational crisis is a period of acute disorganization of affective cognitive and behavioral function precipitated by a traumatic life experience. We review the clinical features of a situational crisis and the four phases of the crisis sequence. Special emphasis is placed on the practical principles of treatment. Recognition of a situational crisis in a patient presenting to the emergency department provides an opportunity for using the initial evaluation as the first step in crisis intervention therapy. This approach often obviates the need for acute hospitalization.

Crisis Intervention↗