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Biomedical subjects

G I Borisov

Publications and source records attributed to G I Borisov.

5 recordsLinked to original sources

[An automated device for x-ray fluorescence analysis and its use in space and clinical medicine].

An experimental unit for radiofluorescent analysis using the REIS-I x-ray emitter, a Si (Li) detector, an analyser with the NOIKA LP-4900 microprocessor and appropriate soft ware was devised for a study of some aspects of metabolism and kinetics of a number of electrolytes playing an important role in the state of water-salt homeostasis of the organism of man and animals. Methodological approaches to quantitative determination of the native content of plasma trace elements and macrocells: S, Cl, K, Ca and stable bromine administered for determination of extracellular fluid volume--were developed. This method can be used for determination of quantitative indices of the above functions in healthy men and animals during outer space flights, ground mock-up experiments, for clinical investigations in diagnosis of subpathological conditions and for control of therapeutic efficacy.

Aerospace Medicine↗

[Effect of space flight factors on hydration homeostasis in monkeys].

Using nuclear physics methods, hydration homeostasis of three monkeys flown on Cosmos-1514 and Cosmos-1667 was investigated. Measurements were made before flight 1.5 hours after touchdown and during the recovery period. Total water content, extracellular and tissue fluid volumes were measured and intracellular and interstitial fluid volumes were calculated. Postflight, all the animals showed hydration status changes of similar sign: total water content, intracellular and extracellular fluid volumes decreased. Most significant changes occurred in tissue and interstitial fluid volumes. Hydration status responses to space flight factors were variable and the above changes disappeared in the course of the recovery period. The variations recorded were viewed as adaptive.

Animals↗

[Characteristics of the hydration status of patients with hypothyroidism].

The hydratation status of 15 patients of various age groups with hypothyrosis was studied using nuclear physical methods. Their body composition was calculated. All the examinees demonstrated considerable hyperhydratation of the extracellular water sector with prevailing liquid accumulation in the interstitial space. Some changes in the infrastructure of the hydratation status including those in the nature of interrelationships of liquid media, were noted. The dependence of the hydratation status and its infrastructure in patients with hypothyrosis on age and gravity of disease but not on its duration was revealed.

Adolescent↗