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Biomedical subjects

G I Nazarenko

Publications and source records attributed to G I Nazarenko.

At least 19 recordsLinked to original sources

[Prognosis of the severity of acute pancreatitis by the neural network method].

For prognozing the character of the development of acute pancreatitis a neural network of the direct spread of the signal was developed with 15 inlets, 5 neurons of the latent layer and two outlets. The network was trained with the help of an algorithm of an inverse spread of the error. The sensitivity of the produced prognostic model was 100%, specificity at admission--70%, on the first day--80%, on the second and third day--90%. Before the moment of hospitalization 57 patients were observed during 72 hours. The diagnosis was confirmed in all cases by the methods of computed tomography with contrast amplification.

APACHE↗

[Current technologies for enhancing efficiency of laboratory techniques].

The current approaches to promoting the efficiency of applying the laboratory tools were comprehensively analyzed. It was for the first time that the above issue was considered from the standpoint of a scientifically substantiated management scheme applicable to the laboratory examination volume and within the framework of the modern conclusive medicine. The problem can be solved through starting, in each clinic, an independent research project and through patient management (critical course--technological card) with respect to available technological and personnel resources. Finally, the basic principles are outlined that are needed for designing the technological cards; the related role of experts in clinical laboratory diagnostics is demonstrated.

Clinical Laboratory Techniques↗

[Significance of parameters of automated reticulocyte analysis in diagnosis and evaluation of treatment outcome in B12-deficient anemia].

The results of examinations of reticulocytes in blood samples of 12 patients with the confirmed diagnosis of B12-deficit anemia and of 20 virtually healthy subjects (control group) by means of the GEN-S hematological analyzer (Beckman-Coulter) are described in the paper. Typical changes of the reticulocyte parameters are defined and their dynamics (with treatment by Vitamin B12) is studied. It was established that the additional parameters of the reticulocyte analysis, characterizing the quantity of immature reticulocytes and the fraction of immature reticulocytes, increase by 3 days before the total quantity of erythrocytes increases, which means that the above parameters can be used earlier as criteria in evaluating the treatment efficiency.

Adult↗

[How to manage patients with atrial fibrillation in a general hospital].

AIM: To evaluate efficacy of use of technological charts (TC) in upgrading management and treatment safety in patients with atrial fibrillation (AF). MATERIAL AND METHODS: Two groups of AF patients were compared: 196 patients treated before introduction of TC (group 1) and 431 patients managed according to TC technology (group 2). RESULTS: In group 2 treatment duration reduced from 26.1 to 18.5 days, rehospitalizations occurred by 6% less frequently, number of unexpected side effects fell 2.5-fold, the rate of varfarin prescription for prevention of thromboembolic complications rose from 18 to 64%, the patients were satisfied with the treatment in 97% vs past 79%. CONCLUSION: TC was a tool of treatment improvement and introduction of the latest clinical recommendations into clinical practice with reference to facilities and staff qualification of an individual hospital without additional financial input.

Aged↗

[Development of navigation technologies for ambulatory surgery].

The article considers the main directions in the development of navigation surgical technologies allowing to decrease traumatic effects of certain operative interventions and to fulfill them in "one day" hospitals. The historical aspects of navigation surgery are given as well as a classification of the navigation interventions and examples of the newest of them used at the present time in the Medical Center of Bank of Russia.

Ambulatory Surgical Procedures↗

[Technologies of ambulatory surgery].

The development of the outpatient surgery in Russia is thought by the authors to be very urgent if compared with the experiences of foreign clinics. In 1998 a Center of the outpatient surgery was set up in the Medical center of the Bank of Russia where the planned surgery treatment was performed in the regimen of the one-day hospitalization. The ultrastructure of the unit and problems of the outpatient surgery technologies are discussed. The first experiences with performing 313 ambulatory interventions concerned with surgery, traumatology and cosmetology are analyzed.

Abortion, Induced↗

[Military medical doctrine and the development of the concept of disaster medicine].

On the basis of their own experience and literature concerning liquidation of the disaster consequences the authors analyse limitations in the disaster health care system. The article shows the trends towards the improvement of medical aid during catastrophes of peaceful period, taking into account various aspects of military doctrine and, especially, the casualty care staging system. It is stressed that the disaster health care procedures will depend on the structure of sanitary losses, characteristic features of the scene of an accident and the dynamics of medical environment.

Disasters↗

Forecasting of the course and outcome of shock in severe mechanical traumas.

The ability to forecast the course and outcome of severe mechanical trauma would aid clinicians in making decisions concerning the treatment of patients. Multifactorial regression models, developed from data obtained from 933 patients with polytrauma and shock, have a high predictive value. A two-part data sheet was developed to give a rating system that predicts the duration of shock in patients that survive and the life span in patients that eventually die. Factors considered in developing the rating system include systemic hemodynamics, hematocrit number, blood density, arteriovenous difference in oxygen saturation, and rectocutaneous temperature gradient, among others.

Adult↗

[The system of evaluation of the severity of injuries (status and prospects of the problem)].

The authors have substantiated the necessity of elaboration and introduction of a single all-state++ system of objective quantitative evaluation of the severity of the injuries. A brief comparative characteristic of the most popular Soviet and foreign systems of the severity of the injuries is presented. The synthesized scales (elaborated at the prognosis laboratory of the Central Institute of Traumatology and Orthopedics ) for a quantitative evaluation of the character and the localization of the fractures are presented.

Adult↗