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Biomedical subjects

G I Roth

Publications and source records attributed to G I Roth.

11 recordsLinked to original sources
PubMed1988

Healing following condylar shave in the monkey temporomandibular joint.

Condylar shaves were performed in monkeys, and the reparative process was studied by histologic and autoradiographic techniques. The condylar surface was found to repair mainly with fibrous connective tissue produced by cells derived from the underlying marrow spaces. The residual condylar cartilage did not play a significant role in this process.

Animals↗
PubMed1987

Identification of patients at risk for unnecessary or excessive TMJ surgery.

Musculoskeletal pain in the head and neck may be associated with a variety of psychological and psychiatric conditions. Therefore, patients with persistent temporomandibular (TMJ) and masticatory muscle complaints must also be evaluated for affective disorders. Identification of patients at risk for unnecessary or excessive TMJ surgery is enhanced when the surgeon is aware of a pattern of persistent pain and illness insistence that characterizes these patients. This article presents a list of characteristics that may identify a patient with an undiagnosed affective disorder who may be exposed to unnecessary treatment.

Anxiety Disorders↗
PubMed1987

Healing following conventional and cryosurgical discoplasty in the monkey temporomandibular joint.

The techniques of conventional discoplasty and the scar producing potential of cryosurgical treatment of the bilaminar region were examined in a study of 17 adult female cynomologous monkeys. Temporomandibular joint (TMJ) tissues were obtained at four and 10 days, four, 20, 52, and 78 weeks after surgery, and compared to TMJ tissues in unoperated control animals. No clinically observable changes in weight, occlusion, or jaw function were identified. All the surgical sites healed normally. At necropsy, lesions of the articular surface of the condyle were apparent in areas that had been surgically "shaved." The anterior, intermediate, and posterior zones of the surgically-treated discs were generally free of change. Two cryosurgically-treated discs showed lesions and perforations. Histologic and autoradiographic observations suggested that the bilaminar area heals quickly with minimal scarring, following both conventional surgical manipulation and cryosurgery. Under the conditions of this experiment the cryosurgical technique was judged not to be superior to the conventional surgical approach.

Animals↗
PubMed1986

Freeze treatment of the monkey mandibular condyle.

Monkey mandibular condyles were frozen in situ and subsequently examined clinically and histologically. The frozen bone served as a structural matrix for the formation of new, vital bone. No ankylosis, open-bite deformity or loss of function was observed.

Animals↗
PubMed1985

Facial pain complaints in the elderly.

The incidence of facial pain and mandibular dysfunction was studied in a population of elderly, middle-class Americans (median age, 71 years) using a self-report questionnaire. The questionnaire was mailed to 839 volunteer subjects of both sexes; responses were obtained from 562 (67%) individuals. Results showed that 536 respondents (95.4%) were free of facial pain and that only 25 (4.4%) had temporomandibular joint pain. Joint sounds and teeth clenching and grinding were associated with facial pain in 50% of those who reported this combination.

Aged↗
PubMedDate not supplied

Macro- and microvascular effects of nitrous oxide in the rat.

The aims of this study were: (1) to determine the macro- and microvascular actions of nitrous oxide (N2O) in the rat, and (2) to determine whether the vascular actions of N2O involved specific interaction with alpha-adrenergic receptors or opioid receptors. Systolic blood pressure, heart rat, total tail blood flow, blood cell velocity in subepidermal capillaries of the tail, and percentage of capillaries exhibiting flow were monitored in conscious rats during the administration of N2O before and after administration of clonidine (an alpha 2-adrenergic agonist), prazosin (an alpha 1-adrenergic antagonist) or naloxone (an opioid antagonist). Total tail blood flow increased significantly in a dose-dependent manner with N2O at 20% and 40% with oxygen. This action of N2O was not blocked by clonidine, prazosin, or naloxone. Capillary flow velocity increased during 20% and 40% N2O compared to 100% O2, but the changes were not statistically significant nor did they correlate with the changes in tail blood flow. These data suggest that the peripheral vascular action of N2O does not involve specific actions at alpha-adrenergic receptors or opioid receptors and may be the result of direct actions on the peripheral vasculature.

Analysis of Variance↗