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Biomedical subjects

G I Tsukerman

Publications and source records attributed to G I Tsukerman.

At least 37 records · Page 2Linked to original sources

[Late results of aortic valve prosthesis (a clinico-hemodynamic analysis)].

Long-term results of aortic-valve ball prosthesis implantation in 184 patients, followed up for about 15 years, are presented. The performance of Soviet-made ball prosthesis in the aortic position has been shown to be fairly satisfactory for a long time. Prostheses of this design are also highly wear-resistant and show satisfactory hydrodynamic properties.

Adult↗

[Mechanisms of mineralization of aortic xenograft bioprostheses in young patients].

The results of mitral valve replacement with aortic xenobioprostheses in 15 patients, aged 14 to 20 years, are presented, the follow-up reaching 7 years. The bioprostheses functioned normally 1.5-2 months after the operation. Within three months to 5 years following the operation, 6 patients developed a bioprosthetic dysfunction that caused death in 4. Histologic and ultrastructural examination revealed signs of tissue destruction and calcinosis that were confirmed by roentgenologic and biochemical findings. The pathogenesis of calcification and tissue destruction of xenobioprostheses is discussed.

Adolescent↗

[Remote results of the correction of mitral valve defects with aortic xenobioprosthesis].

An analysis of the 6-year observations of 84 patients with aortal xenobioprosthesis in the mitral position has shown the bioprostheses to give an adequate and stable correction of hemodynamics, low risk of thromboembolic complications. The anticoagulation therapy was found to be not necessary in most of the patients. The aortal xenobioprostheses in patients older than 20 gave high survival rate (93%) and low risk of specific complications (5,4%). However, great amount of complications in young patients (58%) shows them to be used but for strict indications.

Adolescent↗

[Surgical treatment of multiple heart valve defects].

The article deals with the study of problems of the surgical treatment of patients with multivalvular heart diseases. Problems of myocardial protection, the methods for correcting tricuspid disease, and the attitude towards attendant valvular diseases depending on their severity are discussed on the grounds of the analysis of hospital fatality rate in a group fo 505 patients who underwent one-stage correction of two or three defective heart valves and the appraisal of late results. Analysis of the late results indicates that a more radical approach to the surgical treatment of mitral valvular disease is necessary and that marked relative insufficiency and all forms of organic tricuspid disease must be corrected without fail.

Adolescent↗

[Valve prosthesis in calcified aortic heart defects].

Experience in surgical correction of aortic valvular disease with extreme calcification of valves in 145 patients is generalized. The method for valve prosthetics preventing the development of specific complications is described. On the basis of analysis of the immediate and late postoperative results, it is recommended to use cold cardioplagia for protection of the myocardium. Hospital postoperative mortality was 13.9% in the last 4 years and 10.5% in the last 18 months. Preliminaly coronarography is suggested for the examination of patients with marked angina pectoris and with local changes on the ECG in the group of elderly patients for ruling out a concomitant organic lesion of the coronary artery.

Adolescent↗

[Basic courses of approach to the surgical treatment of postinfarct defects of the interventricular septum].

The authors studied 20 patients with postinfarction ventricular septal defects; among them 9 had been operated on and 2 of these patients died. Eleven patients did not undergo operation, 10 of them died. All patients subjected to operation had severe circulatory insufficiency; in 3 the septal defect was of nor more than one month's duration. Patients whose condition was particularly severe were subjected to intubation, catheterization of the heart, left ventriculo- and coronarography, and after the operation has been planned they were operated on on the same day. Some patients who could move about but who also suffered from circulatory insufficiency were operated on according to the planned schedule. In 10 patients who had died without being operated on the anatomy of the defect and the condition of coronary circulation were examined. The authors contend that before undertaking an operation it is necessary to assess the patient's condition and the possibility of operating on him and determine the role of the ventricular septal defect and the hemodynamic disturbances consequent upon the infarction; all cardiac lesions should be corrected during the operation. Besides closure of the defect and resection of an aneurysm 2 patients also underwent operation for aorticocoronary shunt.

Aged↗

[Results of implanting aortic valve xenografts into the tricuspid position].

From 1968 to 1976 transplantation of the tricuspid valve was performed on 47 patients with combined form of rheumatic heart disease. Hospital mortality was 36%. The follow-up period in 30 cases ranged from one to 7 1/2 years. Ten patients died in the late postoperative periods, only in one of them the cause of death was associated with incompetence of the transplanted valve. According to the findings of dynamic clinical follow-up, the function of the transplant in the other patients was quite satisfactory; at the same time, peculiarities of the phonocardiographic picture of valves treated by different methods were revealed.

Adult↗

[Hemodynamics and the heart volumes of patients before and after mitral valve prosthesis].

The article deals with a complex study of parameters of the hemodynamics and volume of the cardiac cavities in comparison with a clinical state of patients suffering from mitral defect before and in different periods following prosthesis of the mitral valve. On the basis of the results obtained during examination of 54 patients there was revealed a complete conformity between their clinical state, data of the hemodynamics, the volume of the heart and left auricle. A reverse development of many signs characteristic of the defect was established. The absence of an absolute improvement of some clinical and hemodynamic indices in remote periods following the operation in a number of patients was connected with a marked increase of the cardiac volumes before the operation, an unsatisfactory contractile capacity of the myocardium, the remaining of cardiac fibrillation after the operation.

Adolescent↗