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Biomedical subjects

G I Tsukerman

Publications and source records attributed to G I Tsukerman.

89 records · Page 5Linked to original sources
PubMedDate not supplied

[Prosthesis of the aortic valve by a loose allograft].

A procedure has been developed to prepare live aortic allografts, which consists in taking a valve early after a donor's death, sterilizing it in antibiotics and freezing it to -190 degrees C in the presence of the cryoprotective agent dimethylsulfoxide. The preservation of valve tissue is evidenced by morphological studies. The first 3 operations for aortic valvular diseases were performed. In two cases, the indication for surgery was infectious endocarditis refractory to antibiotic therapy. Postimplantation complications were not seen. The competence of the allograft was confirmed by intraoperative transesophageal echocardiographical study. The patients examined 4 months postoperation developed no signs of aortic incompetence and infectious endocarditis. Thus, the creation of a bank of live valves allows this prosthesis to be implanted with appropriate indications, one of which is active infectious endocarditis of the aortic valve.

Adult↗
PubMedDate not supplied

[A trial of the use of EMIKS and LIKS disk prostheses over 10 years].

A total of 2575 EMIKS and LIKS prostheses were implanted to 2309 patients from January 1, 1983 to January 1, 1993. The results were assessed in 1349 patients with primary isolated prostheses of the mitral (PMV), aortic (PAV), and mitral and aortic (PMV + PAV) valves. Mitral valves were replaced in 592 patients, with hospital mortality 3.3%. Aortic valves were replaced in 463 patients, hospital mortality being 2.5. Both the valves were replaced in 289 patients, with hospital mortality 7.6%. A total of 91.8% of patients were examined in periods of up to 9 years after surgery; those were operated on before January 1, 1992. Survival rate by the 9th year postoperation was 88.9 +/- 0.75% of patients with PMV, 88.2 +/- 0.79% with PAV, and 82.1 +/- 0.82% with PMV + PAV. Prosthesis thromboses were observed in 0.05% percent/patient/years, thromboembolism in 1.09% percent/patient/year, prosthetic endocarditis in 0.52 percent/patient/year, paraprosthetic fistulae in 0.63 percent/patient/year. By the 9th year postoperation 86.9 +/- 0.61% of patients with PMV, 96.8 +/- 0.25% of those with PAV, and 88.7 +/- 0.64% of those with PMV + PAV were free from thromboembolic complications.

Adolescent↗