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Biomedical subjects

G I Vinogradov

Publications and source records attributed to G I Vinogradov.

At least 19 recordsLinked to original sources

[Current approach to hygienic evaluation of protective and damaging reactions of the immune system after exposure to environmental factors].

When studying the immune status of the organism the use of additional exposures allow to clear up the defective character of physiological functions even when overt changes are absent. Altitude chamber hypoxia++, reproduction of allergic reactions of the slow and non-slow types, pathogenic Escherichia infection followed by assessment of virulence factors were used as such a stress under exposure to chemicals, electromagnetic fields of radio frequencies. A model was developed for the determination of safe levels of exposure to environmental factors, which makes it possible to differentiate the damaging and defence action of antibodies on the basis of their influence on the fetus and offspring. The effects of antibodies characterized by the postimplantation mortality of fetuses may be used as a criterion of significance for the organism of shifts in immunological reactivity.

Air Pollutants↗

[Functional activity and metabolism of blood neutrophils exposed to low-intensity microwaves].

A 7 hrs exposure of white rats to power density (PD) of 500, 50 and 10 microW/cm2 for 30 days induced changes in phagocytic ability of blood neutrophils, glycogen content and alkaline phosphatase activity. At PD level of 500 microW/cm2 the depression of absorption and digestion functions of neutrophils as well as the decrease of alkaline phosphatase activity and glycogen content were observed during the whole period of aftereffect (three months after exposure). PD levels of 50 and 10 microW/cm2 caused intensification of phagocytic function and metabolism in neutrophils. By the end of the observation period the mentioned indices did not differ from the initial ones.

Alkaline Phosphatase↗