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Biomedical subjects

G Ia Levina

Publications and source records attributed to G Ia Levina.

At least 19 recordsLinked to original sources

[Computed tomography in the diagnosis of intracranial meningiomas].

CT scans in 91 patients revealed the increased density ovoid or circular structures with sharply defined borders to be most characteristic of the intracranial meningiomas. However, these often had densities very low or indistinguishable against the background of the surrounding tissues' absorption coefficients. Irrespective of the initial tumor density CT will reveal the contrast media accumulating in it, diffuse as a rule. Perifocal edema is also typical of the meningiomas, manifested by the early detected shifts and compression fo different brain structures. CT and pathological data compared, the structural features of the meningiomas were identified which determine their density, borders and contrasting media accumulation.

Adolescent↗

[Hypertensive angiopathy of the brain].

Cerebral vessels were studied by light microscopy in 20 autopsies after hemorrhagic stroke from arterial hypertension. Primary (acute), secondary (reparative) changes, as well as changes reflecting compensatory-adaptive processes, were found in the intracerebral and superficial arteries of the brain. The whole complex of these vascular changes was defined as hypertonic angiopathy. The usage of such terms as "angiopathy" and "combined angiopathy" were discussed. Criteria of morphologic diagnosis of angiopathies were proposed.

Adaptation, Physiological↗

[Progressive subcortical arteriosclerotic encephalopathy (Binswanger's disease)].

A case of progressing subcortical arteriosclerotic encephalopathy (Binswanger's disease) in a female of 91 is described; the patient suffered from hypertension with cerebral crises for 40 years. The mechanism of vascular-cerebral insufficiency in the pathogenesis of multiple small foci of complete or incomplete necrosis in various parts of white matter of the cerebral hemisphere characteristic for this disease which is rarely described by pathologists is discussed.

Aged↗

[Hypertonic angioencephalopathy in its pathomorphological aspect].

This is a report on 20 autopsies of patients with arterial hypertension and atherosclerosis who died of a hemorrhagic stroke. Morphological changes characteristic of hypertonic angioencephalopathy were detected in the intracerebral vessels and cerebral substance. They included plasmorrhagia with arterial stenosis and necrosis, miliary aneurysms, isolated necrosis of the pia mater attended with vascular deformation, complete and incomplete necrosis of the cerebral substance, gliomesodermal cicatrices, perivascular hemorrhages, lacunar infarctions at various stages of their progression, etc. The pathomorphological classification of cerebral circulation impairments has thus incorporated an additional notion "hypertonic angioencephalopathy".

Brain↗

[Hypersomnic syndrome in circulatory disorders of the oral portions of the brain stem (clinico-morphologic observations)].

Hypersomnia is described in 11 patients who have had a cerebral circulation episode with prevalent localization of the lesion in the oral divisions of the brain trunk. Three morphological observations are presented: these were cases of bilateral affection of certain meso- and diencephalic structures, e.g. medial divisions of the thalami and the diencephalon cover with involvement of the grey matter of the Sylvian aqueduct into the process. The observations presented confirm the opinion that the nonspecific structures of the meso- and diencephalic region are a part of the complex cortico-subcortical system participating in maintaining the state of wakefulness.

Aged↗

[Morphologic verification in computer tomography of the brain].

A comparison of computer-aided tomograms of the brain with the results of morphological examinations of the latter in 51 autopsy cases was carried out. The causes of the death were brain infarctions, hemorrhages, and tumours. It was found that roentgenological diagnosis of cerebral infarctions entailed no difficulties, if the examinations were performed within 24 hours after the disease onset and the focus size was over 1 to 2 cm. There were some difficulties in diagnosing small foci in the brain stem and in the cortex of brain hemispheres as well as infarctions with hemorrhages irrespectively of their size and location. The diagnoses of cerebral hemorrhages were rather precise in the early stages of hemorrhagic strokes, but extremely difficult later, in a definite stage of the hemorrhagic focus organization when computer-aided tomography revealed densities characteristic for unaffected brain. A high diagnostic efficiency of the computer-aided tomography was noted in brain tumours. Certain difficulties sometimes arose in determining the character of the tumour in cases of multiple of small-size foci. The morphological verification of the results of the computer-aided brain tomography is of a decisive importance for developing roentgenomorphological criteria for diagnosing CNS pathologies with the aid of this method, and contributes to further improvement of the latter.

Brain↗

[Cerebellar infarct in hypertensive crisis].

The paper reports an unusual pathogenetic mechanism of the cerebral circulation disorder in hypertensive crisis. Cerebellar infarction developed as a result of compression in great occipitae foramen of the inferior posterior cerebellar artery which was a complication of a severe hypertensive crisis with cerebral edema and a shift of stem structures into the great occipitae foramen. Of great importance in the parthogenesis of infarction was a rarely occuring variant of the course of the right inferior posterior cerebellar artery.

Cerebellum↗

[Secondary stem syndrome following infarcts and hemorrhages into the cerebral hemispheres].

The authors analyse the significance of some factors for the development of a clinical, electroencephalographic and electrocardiographic picture of the secondary dysfunction of stem brain structures in patients suffering from strokes with a hemispheric localization of the focus. A great complexity and different influences of the course of stages of the secondary stem syndrome are stressed. Attention is drawn to the expedience of using repeated EEG recording in the acute phase of a stroke for diagnostic purposes.

Autonomic Nervous System↗

[Atherosclerosis of the vessels of Willis' circle in certain variants in its structure].

Random studies of the base of the brain vessels in 278 men who had died at the age of 50--64 years were carried out; 29 variants of the structure of the circle of Willis were established; the most common were threadlike connective arteries and posterior trifurcations of the inner carotid arteries. The investigation of atherosclerotic changes in every vessel of the base of the brain showed that in the so-called posterior trifurcations there was a statistically reliable growth of the average degree of atherosclerosis in the intracranial region of the inner carotid artery ensuring in these cases the blood supply for a considerably greater region of the brain. In posterior connective arteries atherosclerotic changes were revealed only when their diametre exceeded 0.1 cm which testified to the bloodflow in these arteries.

Carotid Artery, Internal↗

[Morphologic changes in an artery feeding an arteriovenous aneurysm over a long period following its embolization].

Different materials are used in operations for embolization of arteriovenous aneurysms on which radical operation cannot be performed. A case is described with successful embolization by means of silicon-tantulum balls of vessels supplying a giant arteriovenous aneurysm. The patient died 6 years after operation from recurrent massive hemorrhage with escape of blood into the ventricles. Morphological examination of the artery revealed neither necrotic or inflammatory changes in its walls at the site of the embolism.

Adult↗