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Biomedical subjects

G J Barnes

Publications and source records attributed to G J Barnes.

6 recordsLinked to original sources

Management of dysphagia in inclusion body myositis.

Inclusion body myositis is an inflammatory myopathy in which dysphagia has been considered a rare finding. However, recent literature finds dysphagia an increasingly common symptom as more cases of inclusion body myositis are identified. Unlike some inflammatory myopathic disorders, inclusion body myositis is resistant to treatment with corticosteroids, and therefore, the otolaryngologist may be consulted regarding surgical options for relief of dysphagia. A patient is described in whom severe progressive dysphagia associated with inclusion body myositis developed. Impaired pharyngeal wall motion and cricopharyngeal achalasia were demonstrated by videofluoroscopic evaluation, and the patient was successfully treated by cricopharyngeal myotomy. The pathophysiologic nature of inclusion body myositis and the mechanisms of cervical dysphagia in the inflammatory myopathies are reviewed.

Aged↗

Vocal tract steadiness: a measure of phonatory and upper airway motor control during phonation in dysarthria.

Acoustic analyses of upper airway and phonatory stability were conducted on samples of sustained phonation to evaluate the relation between laryngeal and articulomotor stability for 31 patients with dysarthria and 12 non-dysarthric control subjects. Significantly higher values were found for the variability in fundamental frequency and format frequency of patients who have Huntington's disease compared with normal subjects and patients with Parkinson's disease. No significant correlations were found between format frequency variability and the variability of the fundamental frequency for any subject group. These findings are discussed as they pertain to the relationship between phonatory and upper airway subsystems and the evaluation of vocal tract motor control impairments in dysarthria.

Adult↗

Effects of phonetic distance on recognition of synthetic sentences.

Phonetic replacements for the syllable initial consonants and clusters of words in sentences were made according to the scale of phonetic distance devised by Black (Perceptual Differences Between Consonants. Columbus: The Ohio State University, 1974). The impact of such replacements upon the intelligibility of synthetically produced sentences was shown to be substantial. The regression of intelligibility over distance was strong, providing support for the construct validity of Black's scaling.

Female↗