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Biomedical subjects

G J McNeillage

Publications and source records attributed to G J McNeillage.

11 recordsLinked to original sources

The prevalence of antibodies reactive with Campylobacter jejuni in the serum of homosexual men.

Samples of serum from 187 homosexual and 169 heterosexual men were examined by means of an indirect immunofluorescent antibody test for the presence of antibody reactive with Campylobacter jejuni. Antibody of the IgG class was detected in the serum of 19 (10.2 per cent) and 15 (8.9 per cent) homo- and heterosexual men respectively. The prevalence of serum antibody in men attending a sexually transmitted diseases clinic was higher than in a previously reported control group.

Adolescent↗

Comparison of the sensitivity of microscopy and culture in the laboratory diagnosis of intestinal protozoal infection.

Concentration of protozoal cysts from faeces by the formol-ether method and faecal culture on Robinson's medium were studied to determine their diagnostic value among patients attending a sexually transmitted diseases clinic in Edinburgh. Of 450 men studied Entamoeba histolytica and Giardia lamblia were identified in the faeces of 10.7 and 5.1% respectively. Thirty (81.1%) of 37 men with E histolytica and 11 (47.8%) of 23 men with G lamblia infections would not have been identified if formol-ether concentration had not been undertaken. Culture of faeces in Robinson's medium led to the detection of a further 11 men with amoebiasis. Oocysts of Cryptosporidium spp were not identified in faecal samples from 130 men.

Coccidiosis↗

Proctitis in homosexual men. A diagnostic problem.

One hundred and seventy six men with histories of anal intercourse were studied to determine if there was a correlation between the clinical features, cytological findings in the mucosal secretions, and the histological appearance of the rectal mucosa. The presence or absence of gastrointestinal symptoms did not differentiate between patients with and without proctitis. Sigmoidoscopy was normal in each of the 117 men with normal rectal histology. Macroscopic abnormalities were evident in the mucosa of nine of 11 men with infective proctitis, and sigmoidoscopy was normal in 40 of the 48 men with chronic proctitis. Cytological examination was often useful in detecting infective proctitis but not chronic proctitis.

Adolescent↗