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Biomedical subjects

G J Rodgers

Publications and source records attributed to G J Rodgers.

8 recordsLinked to original sources

Complex growing networks with intrinsic vertex fitness.

One of the major questions in complex network research is to identify the range of mechanisms by which a complex network can self organize into a scale-free state. In this paper we investigate the interplay between a fitness linking mechanism and both random and preferential attachment. In our models, each vertex is assigned a fitness x, drawn from a probability distribution rho(x). In Model A, at each time step a vertex is added and joined to an existing vertex, selected at random, with probability p and an edge is introduced between vertices with fitnesses x and y, with a rate f(x,y), with probability 1-p. Model B differs from Model A in that, with probability p, edges are added with preferential attachment rather than randomly. The analysis of Model A shows that, for every fixed fitness x, the network's degree distribution decays exponentially. In Model B we recover instead a power-law degree distribution whose exponent depends only on p, and we show how this result can be generalized. The properties of a number of particular networks are examined.

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Network properties of written human language.

We investigate the nature of written human language within the framework of complex network theory. In particular, we analyze the topology of Orwell's "1984" focusing on the local properties of the network, such as the properties of the nearest neighbors and the clustering coefficient. We find a composite power law behavior for both the average nearest neighbor's degree and average clustering coefficient as a function of the vertex degree. This implies the existence of different functional classes of vertices. Furthermore, we find that the second order vertex correlations are an essential component of the network architecture. To model our empirical results we extend a previously introduced model for language due to Dorogovtsev and Mendes. We propose an accelerated growing network model that contains three growth mechanisms: linear preferential attachment, local preferential attachment, and the random growth of a predetermined small finite subset of initial vertices. We find that with these elementary stochastic rules we are able to produce a network showing syntacticlike structures.

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Spin-glass phase transition on scale-free networks.

We study the Ising spin-glass model on scale-free networks generated by the static model using the replica method. Based on the replica-symmetric solution, we derive the phase diagram consisting of the paramagnetic (P), ferromagnetic (F), and spin glass (SG) phases as well as the Almeida-Thouless line as functions of the degree exponent lambda, the mean degree K, and the fraction of ferromagnetic interactions r. To reflect the inhomogeneity of vertices, we modify the magnetization m and the spin-glass order parameter q with vertex- weights. The transition temperature T(c) (T(g)) between the P-F (P-SG) phases and the critical behaviors of the order parameters are found analytically. When 2 1/2, while it is in the SG phase at r=1/2. m and q decay as power-laws with increasing temperature with different lambda-dependent exponents. When lambda>3, the T(c) and T(g) are finite and related to the percolation threshold. The critical exponents associated with m and q depend on lambda for 3<lambda<5 (3<lambda<4) at the P-F (P-SG) boundary.

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Traffic on complex networks: Towards understanding global statistical properties from microscopic density fluctuations.

We study the microscopic time fluctuations of traffic load and the global statistical properties of a dense traffic of particles on scale-free cyclic graphs. For a wide range of driving rates R the traffic is stationary and the load time series exhibits antipersistence due to the regulatory role of the superstructure associated with two hub nodes in the network. We discuss how the superstructure affects the functioning of the network at high traffic density and at the jamming threshold. The degree of correlations systematically decreases with increasing traffic density and eventually disappears when approaching a jamming density R(c). Already before jamming we observe qualitative changes in the global network-load distributions and the particle queuing times. These changes are related to the occurrence of temporary crises in which the network-load increases dramatically, and then slowly falls back to a value characterizing free flow.

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Bose-Einstein condensation in random directed networks.

We consider the phenomenon of Bose-Einstein condensation in a random growing directed network. The network grows by the addition of vertices and edges. At each time step the network gains a vertex with probability p and an edge with probability 1-p. The new vertex has a fitness (a,b) a,b>0, with probability f(a,b). A vertex with fitness (a,b), with in-degree i and out-degree j, gains a new incoming edge with rate a(i+1) and an outgoing edge with rate b(j+1). The Bose-Einstein condensation occurs as a function of fitness distribution f(a,b).

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Exact solution of a generalized model for surface deposition.

We consider a model for surface deposition in one dimension, in the presence of both precursor-layer diffusion and desorption. The model is a generalization that includes random sequential adsorption (RSA), accelerated RSA, and growth-and-coalescence models as special cases. Exact solutions are obtained for the model for both its lattice and continuum versions. Expressions are obtained for physically important quantities such as the surface coverage, average island size, mass-adsorption efficiency, and the process efficiency. The connection between a limiting case of the model and epidemic models is discussed.

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Degree distributions of growing networks.

The in-degree and out-degree distributions of a growing network model are determined. The in-degree is the number of incoming links to a given node (and vice versa for out-degree). The network is built by (i) creation of new nodes which each immediately attach to a preexisting node, and (ii) creation of new links between preexisting nodes. This process naturally generates correlated in-degree and out-degree distributions. When the node and link creation rates are linear functions of node degree, these distributions exhibit distinct power-law forms. By tuning the parameters in these rates to reasonable values, exponents which agree with those of the web graph are obtained.

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Measurement in vitro of pulsatile arterial diameter using a helium-neon laser.

A noncontacting in vitro measurement of pulsatile arterial diameter using a scanning optical micrometer is described. The major component of this system is a He-Ne laser whose beam scans the pulsating artery to be measured. The laser micrometer was integrated into a pulsatile perfusion apparatus that imposed various hemodynamic conditions on excised canine vessels. The laser system reliably tracked the pulsating arterial diameter at a particular longitudinal site as well as at various increments in the presence of an experimentally created stenosis. The He-Ne laser measured the radial motion of canine arteries and various vascular substitutes anastomosed in an end-to-end fashion. From these novel measurements, calculations were made of arterial compliance and bending stress, two biomechanical parameters that are implicated as potential causes of anastomotic intimal hyperplasia and graft failure. Although this device is inherently limited to in vitro use, it is a potentially useful instrument for vascular physiology and biophysics.

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