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G J Wannan

Publications and source records attributed to G J Wannan.

3 recordsLinked to original sources

HIV seroprevalence amongst pregnant women in northeastern Zaire.

To assess the seroprevalence of HIV in pregnant women in northeastern Zaire and factors that correlate with seropositivity, sequential blood sampling and interviews were performed on 700 women at antenatal clinics in northeastern Zaire. The seroprevalence of the 3 clinics surveyed varied from 0.3%-5.5%, rates being higher in more urban areas. Seropositivity was associated with greater education (P<0.001) and having a partner whose job involved travelling (P<0.001). No correlation was found with marital status, age, or gravidity. Women in northeastern Zaire are at a greater risk of being infected with HIV if they are well educated or have a husband who travels due to his work. Health education on HIV should be particularly directed at women who are well educated and at men who have 'mobile' jobs.

Democratic Republic of the Congo

Rapid HIV tests.

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AIDS Serodiagnosis

How many bloods will a 'HIVCHEK' check? Multiple tests for HIV antibody for a single screening kit.

Detection of HIV infection in blood donors or populations is usually by testing sera for antibodies to HIV-1 and HIV-2. Screening tests are now highly sensitive and specific, but still expensive and scarce in Africa. We tested the commercially available kits 'HIVCHEK 1 + 2' in two field laboratories, on specimens from blood donors and antenatal women in rural Zaire. We describe a method of using one test kit for up to five serum samples, saving money and time. In 491 antenatal mothers in Eastern Zaire, among whom the HIV seroprevalence was 3.3%, we compared 'HIVCHEK' results with results obtained by ELISA and Western blot. The 'HIVCHEK' multiple-sample method had a sensitivity of 82% and a specificity of 99.6%. In an area with an HIV seroprevalence of < 4%, using 'HIVCHEK' by the multiple sample method would lead to a saving of about 2,400 pounds for every 1000 individuals tested.

AIDS Serodiagnosis